Results 21 to 30 of about 891 (153)

Clinical Features, Diagnosis, and Treatment Plans of Balamuthia mandrillaris Encephalitis in Pediatrics: A Systematic Review [PDF]

Journal of Pediatrics Review
Background: Balamuthia mandrillaris is a free-living amoeba responsible for a rare but fatal microbial encephalitis in pediatric patients. Pediatric cases are extremely rare and typically present with nonspecific symptoms, leading to delayed diagnosis ...
Hoda Mehrabi, Reza Ghasemikhah
doaj   +2 more sources

18F-FDG PET/CT findings in fatal Balamuthia Mandrillaris encephalitis in brain stem: A case report

Radiology Case Reports
We presented a case of a 66-year-old female whose initial symptom was headache without obvious inducement. The patient's condition progressed rapidly to a semi-coma state after symptomatic treatment.
Hualei Xu, Dawei Wang, Kunwei Cui, Ruimei Wan, Quan Chi, Tao Wu   +5 more
doaj   +2 more sources

Modelling amoebic brain infection caused by Balamuthia mandrillaris using a human cerebral organoid.

PLoS Neglected Tropical Diseases
The lack of disease models adequately resembling human tissue has hindered our understanding of amoebic brain infection. Three-dimensional structured organoids provide a microenvironment similar to human tissue.
Nongnat Tongkrajang, Porntida Kobpornchai, Pratima Dubey, Urai Chaisri, Kasem Kulkeaw   +4 more
doaj   +2 more sources

Etymologia: Balamuthia mandrillaris

Emerging Infectious Diseases, 2015
doaj   +2 more sources

A devastating case of a Balamuthia mandrillaris pediatric brain infection

Radiology Case Reports
Balamuthia mandrillaris is an amoeba that causes an uncommon but deadly encephalitis, referred to as granulomatous amoebic encephalitis (GAE). The highest incidence reported worldwide has occurred in America, and within the United States, it has been ...
Kathryn A. Szymanski, Michael S. Kuwabara, Neil Friedman, C. Pfeifer   +3 more
semanticscholar   +4 more sources

The transcriptome of Balamuthia mandrillaris trophozoites for structure-guided drug design

Scientific Reports, 2021
Balamuthia mandrillaris, a pathogenic free-living amoeba, causes cutaneous skin lesions as well as granulomatous amoebic encephalitis, a ‘brain-eating’ disease.
Isabelle Q. Phan, Christopher A. Rice, Justin Craig, Rooksana E. Noorai, Jacquelyn R. McDonald, Sandhya Subramanian, Logan Tillery, Lynn K. Barrett, Vijay Shankar, James C. Morris, Wesley C. Van Voorhis, Dennis E. Kyle, Peter J. Myler   +12 more
doaj   +1 more source

Disseminated Balamuthia mandrillaris Infection [PDF]

Journal of Clinical Microbiology, 2015
ABSTRACTBalamuthia mandrillarisis a rare cause of human infection, but when infections do occur, they result in high rates of morbidity and mortality. A case of disseminatedBalamuthiainfection is presented. Early diagnosis and initiation of recommended therapy are essential for increased chances of successful outcomes.
Katherine R, Schafer, Neil, Shah, M I, Almira-Suarez, Jennifer M, Reese, George M, Hoke, James W, Mandell, Sharon L, Roy, Govinda, Visvesvara   +7 more
openaire   +2 more sources

Guidelines for the purification and characterization of extracellular vesicles of parasites

Journal of Extracellular Biology, Volume 2, Issue 10, October 2023., 2023
Abstract Parasites are responsible for the most neglected tropical diseases, affecting over a billion people worldwide (WHO, 2015) and accounting for billions of cases a year and responsible for several millions of deaths. Research on extracellular vesicles (EVs) has increased in recent years and demonstrated that EVs shed by pathogenic parasites ...
Carmen Fernandez‐Becerra, Patrícia Xander, Daniel Alfandari, George Dong, Iris Aparici‐Herraiz, Irit Rosenhek‐Goldian, Mehrdad Shokouhy, Melisa Gualdron‐Lopez, Nicholy Lozano, Nuria Cortes‐Serra, Paula Abou Karam, Paula Meneghetti, Rafael Pedro Madeira, Ziv Porat, Rodrigo Pedro Soares, Adriana Oliveira Costa, Sima Rafati, Anabela‐Cordeiro da Silva, Nuno Santarém, Christopher Fernandez‐Prada, Marcel I. Ramirez, Dolores Bernal, Antonio Marcilla, Vera Lucia Pereira‐Chioccola, Lysangela Ronalte Alves, Hernando Del Portillo, Neta Regev‐Rudzki, Igor Correia de Almeida, Sergio Schenkman, Martin Olivier, Ana Claudia Torrecilhas   +30 more
wiley   +1 more source

A Case of Balamuthia mandrillaris Meningoencephalitis [PDF]

Archives of Neurology, 2000
Balamuthia mandrillaris is a newly described pathogen that causes granulomatous amebic encephalitis, an extremely rare clinical entity that usually occurs in immunosuppressed individuals. We report a case of pathologically proven Balamuthia encephalitis with unusual laboratory and radiologic findings.
J D, Katz, A H, Ropper, L, Adelman, M, Worthington, P, Wade   +4 more
openaire   +2 more sources

An autopsy case of granulomatous amebic encephalitis caused by Balamuthia mandrillaris involving prior amebic dermatitis

Neuropathology, Volume 42, Issue 3, Page 190-196, June 2022., 2022
An 82‐year‐old man, who was healthy and had worked as a farmer, experienced worsening neurological symptoms over a seven‐month period, which eventually caused his death. Multiple fluctuating brain lesions were detected radiographically. Clinically, sarcoidosis was ranked high among the differential diagnoses because of the presence of skin lesions ...
Tatsuro Maehara, Tetsushi Mizuno, Masaharu Tokoro, Tatsuru Hara, Yui Tomita, Kouki Makioka, Sei‐Ichiro Motegi, Ayako Yamazaki, Nozomi Matsumura, Sumihito Nobusawa, Hideaki Yokoo   +10 more
wiley   +1 more source