Results 11 to 20 of about 1,776 (195)

Balamuthia mandrillaris infection in China: a retrospective report of 28 cases [PDF]

Emerging Microbes and Infections, 2020
Balamuthia mandrillaris infection is a rare and fatal disease. We have recorded 28 cases of Balamuthia mandrillaris infection during the past 20 years. Eighteen patients (64%) were male and 10 (36%) were female. Patient age ranged from 3 to 74 (mean, 27)
Lei Wang, Wenjing Cheng, Bing Li, Zhe Jian, Xianlong Qi, Dongjie Sun, Jian Gao, Xuetao Lu, Yi Yang, Kun Lin, Chuanlong Lu, Jiaxi Chen, Chunying Li, Gang Wang, Tianwen Gao   +14 more
doaj   +4 more sources

Diagnosing Balamuthia mandrillaris encephalitis via next-generation sequencing in a 13-year-old girl [PDF]

Emerging Microbes and Infections, 2020
Balamuthia amoebic encephalitis has a subacute-to-chronic course and is almost invariably fatal owing to delayed diagnosis and a lack of effective therapy.
Xia Wu, Gangfeng Yan, Shuzhen Han, Yingzi Ye, Xunjia Cheng, Hairong Gong, Hui Yu   +6 more
doaj   +4 more sources

An Optical and Chemiluminescence Assay for Assessing the Cytotoxicity of Balamuthia mandrillaris against Human Neurospheroids [PDF]

Bioengineering, 2022
A spheroid is a cell aggregate in a three-dimensional context; thereby, it recapitulates the cellular architecture in human tissue. However, the utility of spheroids as an assay for host–parasite interactions remains unexplored.
Worakamol Pengsart, Kasem Kulkeaw
doaj   +2 more sources

Functional annotation and comparative genomics analysis of Balamuthia mandrillaris reveals potential virulence-related genes [PDF]

Scientific Reports, 2023
Balamuthia mandrillaris is a pathogenic protozoan that causes a rare but almost always fatal infection of the central nervous system and, in some cases, cutaneous lesions. Currently, the genomic data for this free-living amoeba include the description of
Alejandro Otero-Ruiz, Libia Zulema Rodriguez-Anaya, Fernando Lares-Villa, Luis Fernando Lozano Aguirre Beltrán, Luis Fernando Lares-Jiménez, Jose Reyes Gonzalez-Galaviz, Abraham Cruz-Mendívil   +6 more
doaj   +2 more sources

The role of plasma metagenomic sequencing in identification of Balamuthia mandrillaris encephalitis [PDF]

Acta Neuropathologica Communications
Balamuthia mandrillaris is a rare, free-living amoeba (FLA) that causes granulomatous amoebic encephalitis, a disease with close to 90% mortality. The geographical ranges of many FLA are expanding, potentially increasing human exposure to B. mandrillaris.
Sarah Y. Edminster, Ryan W. Rebbe, Christopher Khatchadourian, Kyle M. Hurth, Anna J. Mathew, Julie Huss-Bawab, Mark S. Shiroishi, Devin Clark, Andrew P. Norgan, Susan M. Butler-Wu, Annie Hiniker   +10 more
doaj   +2 more sources

Fatal amoebic meningoencephalitis caused by Balamuthia mandrillaris in Pongo pygmaeus and first case report in Pan troglodytes verus [PDF]

Frontiers in Veterinary Science
Balamuthia mandrillaris is an amoeba that can cause granulomatous amoebic encephalitis (GAE) as well as lung and skin infections in both humans and animals. Studies on B. mandrillaris-related GAE cases have increased in recent years. This amoeba has been
Rubén L. Rodríguez-Expósito, Rubén L. Rodríguez-Expósito, Rubén L. Rodríguez-Expósito, Loles Carbonell, Jesús Recuero-Gil, Javier Martinez, Rosa Martinez-Valverde, Carmen Martinez-Fernandez, Joaquín Ortega-Porcel, Agustín Barragán Hernández, Juan M. Corpa, Estefanía Montero Cortijo, Jesús Sánchez-Nicolás, Sergio Moya, Patricia Pérez-Pérez, Patricia Pérez-Pérez, María Reyes-Batlle, María Reyes-Batlle, María Reyes-Batlle, Angélica Domíngez-de-Barros, Angélica Domíngez-de-Barros, Omar García-Pérez, Omar García-Pérez, Angela Magnet, Fernando Izquierdo, Soledad Fenoy, Carmen del Águila, Elizabeth Córdoba-Lanús, Elizabeth Córdoba-Lanús, Francisco de Asis García-González, Miguel Casares, José E. Piñero, José E. Piñero, José E. Piñero, Jacob Lorenzo-Morales, Jacob Lorenzo-Morales, Jacob Lorenzo-Morales   +36 more
doaj   +2 more sources

Balamuthia mandrillaris trophozoites ingest human neuronal cells via a trogocytosis-independent mechanism [PDF]

Parasites & Vectors, 2022
Background Environmental protozoa need an adaptation mechanism to survive drastic changes in niches in the human body. In the brain parenchyma, Balamuthia mandrillaris trophozoites, which are causative agents of fatal brain damage, must acquire nutrients
Worakamol Pengsart, Nongnat Tongkrajang, Narisara Whangviboonkij, Patsharaporn Techasintana Sarasombath, Kasem Kulkeaw   +4 more
doaj   +2 more sources

Antiamoebic Properties of Laboratory and Clinically Used Drugs against Naegleria fowleri and Balamuthia mandrillaris [PDF]

Antibiotics, 2022
Naegleria fowleri and Balamuthia mandrillaris are pathogenic free-living amoebae that infect the central nervous system with over 95% mortality rates.
Ruqaiyyah Siddiqui, Mohammad Ridwane Mungroo, Tengku Shahrul Anuar, Ahmad M. Alharbi, Hasan Alfahemi, Adel B. Elmoselhi, Naveed Ahmed Khan   +6 more
doaj   +2 more sources

Antiamoebic Properties of Metabolites against Naegleria fowleri and Balamuthia mandrillaris [PDF]

Antibiotics, 2022
Naegleria fowleri and Balamuthia mandrillaris are free-living, opportunistic protists, distributed widely in the environment. They are responsible for primary amoebic meningoencephalitis (PAM) and granulomatous amoebic encephalitis (GAE), the fatal ...
Ruqaiyyah Siddiqui, Anania Boghossian, Bushra Khatoon, Muhammad Kawish, Ahmad M. Alharbi, Muhammad Raza Shah, Hasan Alfahemi, Naveed Ahmed Khan   +7 more
doaj   +2 more sources

Balamuthia mandrillaris: An opportunistic, free-living ameba - An updated review.

Trop Parasitol, 2021
Balamuthia mandrillaris is an opportunistic, free-living ameba that is pathogenic to humans. It has a worldwide distribution but is mainly detected in warmer regions. Balamuthia infections are rare but have been reported in both immunocompetent and immunocompromised individuals of all ages. B.
Bhosale NK, Parija SC.
europepmc   +3 more sources