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Free‐Living Amoebas in Extreme Environments: The True Survival in our Planet
Free‐living amoebas (FLAs) are microorganisms, unicellular protozoa widely distributed in nature and present in different environments, such as water or soil; they are maintained in ecosystems and play a fundamental role in the biological control of bacteria, other protozoa, and mushrooms.
Camila Salazar-Ardiles +3 more
wiley +1 more source
Balamuthia mandrillaris resistance to hostile conditions [PDF]
The resistance of Balamuthia mandrillaris to physical, chemical and radiological conditions was tested. Following treatments, viability was determined by culturing amoebae on human brain microvascular endothelial cells for up to 12 days. B. mandrillaris cysts were resistant to repeated freeze–thawing (five times), temperatures of up to 70 °C, 0.5 % SDS,
Ortega Rivas, Antonio +2 more
openaire +3 more sources
Drugs used for the treatment of cerebral and disseminated infections caused by free‐living amoebae
Abstract Free‐living amoebae (FLAs) are protozoa developing autonomously in diverse natural or artificial environments. The FLAs Acanthamoeba spp., Balamuthia mandrillaris, and Naegleria fowleri represent a risk for human health as they can become pathogenic and cause severe cerebral infections, named granulomatous amoebic encephalitis (GAE ...
Alexandre Taravaud +3 more
wiley +1 more source
Fatal Balamuthia mandrillaris brain infection associated with improper nasal lavage
We report the case of a 69-year-old female who presented with a chronic nasal skin rash, new onset focal seizure, and a cerebral ring-enhancing lesion after a year of improper nasal irrigation.
Keenan J. Piper +5 more
doaj +1 more source
Increasing Importance of Balamuthia mandrillaris [PDF]
SUMMARY Balamuthia mandrillaris is an emerging protozoan parasite, an agent of granulomatous amoebic encephalitis involving the central nervous system, with a case fatality rate of >98%. This review presents our current understanding of Balamuthia infections, their ...
Abdul, Matin +3 more
openaire +2 more sources
A 76‐year‐old male with multiple enhancing brain lesions
Brain Pathology, Volume 32, Issue 3, May 2022.
Kathryn L. Eschbacher +5 more
wiley +1 more source
A Japanese case of amoebic meningoencephalitis initially diagnosed by cerebrospinal fluid cytology
Microscopy can detect the presence of amoebic trophozoites in cerebrospinal fluid and tissue. The infection was confirmed in the present case by polymerase chain reaction and immunohistochemistry, but we were unable to achieve a cure. Our case rapidly progressed without any skin lesions.
Ryogo Aoki +8 more
wiley +1 more source
Background Balamuthia granulomatous amoebic encephalitis (GAE) is a peculiar parasitic infectious disease of the central nervous system, about 39% of the infected Balamuthia GAE patients were found to be immunocompromised and is extremely rare clinically.
Jun Liu +6 more
doaj +1 more source
Microglia in neuropathology caused by protozoan parasites
ABSTRACT Involvement of the central nervous system (CNS) is the most severe consequence of some parasitic infections. Protozoal infections comprise a group of diseases that together affect billions of people worldwide and, according to the World Health Organization, are responsible for more than 500000 deaths annually. They include African and American
Katherine Figarella +3 more
wiley +1 more source
A spheroid is a cell aggregate in a three-dimensional context; thereby, it recapitulates the cellular architecture in human tissue. However, the utility of spheroids as an assay for host–parasite interactions remains unexplored.
Worakamol Pengsart, Kasem Kulkeaw
doaj +1 more source

