Fatal granulomatous amoebic encephalitis caused by Balamuthia mandrillaris
Medical Journal of Australia, 1997 Granulomatous amoebic encephalitis caused by Balamuthia mandrillaris is rare (63 human) cases reported worldwide) and fatal. We report a case in a five-year-old boy who had previously been well. For 18 months, he had had a slowly progressive, granulomatous mid facial lesion, but despite extensive investigation definitive diagnosis was made only with ...
Reed, R.P. +6 more
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Modelling amoebic brain infection caused by Balamuthia mandrillaris using a human cerebral organoid. [PDF]
PLoS Neglected Tropical DiseasesThe lack of disease models adequately resembling human tissue has hindered our understanding of amoebic brain infection. Three-dimensional structured organoids provide a microenvironment similar to human tissue.
Nongnat Tongkrajang +4 more
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The cyst wall carbohydrate composition of Balamuthia mandrillaris
Parasitology Research, 2009 Balamuthia mandrillaris is an opportunistic cyst-producing amoeba that can cause rare, but fatal, Balamuthia amoebic encephalitis (BAE). Cysts are resistant to harsh environmental conditions and many antimicrobial compounds and thus can contribute to BAE recurrence.
Ruqaiyyah, Siddiqui +2 more
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Detection of
BMC Microbiology, 2008 Background The free-living amoeba Balamuthia mandrillaris may cause fatal encephalitis both in immunocompromised and in – apparently – immunocompetent humans and other mammalian species. Rapid, specific, sensitive, and reliable detection requiring little
Lewin Astrid +2 more
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Isolation and Environmental Detection of Balamuthia mandrillaris in Isfahan, Iran. [PDF]
Environ Microbiol RepThis study investigates the presence of Balamuthia mandrillaris in environmental sources from Isfahan, Iran, and compares cultural and molecular detection methods. The findings highlight matrix‐dependent detection patterns and report an overall prevalence of 15.6%.
Lesani S, Mirzania S, Eskandarian A.
europepmc +2 more sources
Balamuthia mandrillaris – a brief overview of the parasite causing encephalitis
Microbial PathogenesisBalamuthia mandrillaris is a unicellular protist, known to cause infection of the central nervous system. The life cycle of B. mandrillaris is divided into vegetative, infectious trophozoites and dormant cysts. The ability of B. mandrillaris to produce a rare but fatal infection has resulted in considerable interest in this parasite by the scientific ...
Ruqaiyyah Siddiqui +3 more
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An autopsy case of granulomatous amebic encephalitis caused by Balamuthia mandrillaris involving prior amebic dermatitis. [PDF]
Neuropathology, 2022 An 82‐year‐old man, who was healthy and had worked as a farmer, experienced worsening neurological symptoms over a seven‐month period, which eventually caused his death. Multiple fluctuating brain lesions were detected radiographically. Clinically, sarcoidosis was ranked high among the differential diagnoses because of the presence of skin lesions ...
Maehara T +10 more
europepmc +2 more sources
<i>Balamuthia mandrillaris</i>: An opportunistic, free-living ameba - An updated review. [PDF]
Trop Parasitol, 2021 Balamuthia mandrillaris is an opportunistic, free-living ameba that is pathogenic to humans. It has a worldwide distribution but is mainly detected in warmer regions. Balamuthia infections are rare but have been reported in both immunocompetent and immunocompromised individuals of all ages. B.
Bhosale NK, Parija SC.
europepmc +3 more sources
Antiamoebic Properties of Metabolites against Naegleria fowleri and Balamuthia mandrillaris. [PDF]
Antibiotics (Basel), 2022 Naegleria fowleri and Balamuthia mandrillaris are free-living, opportunistic protists, distributed widely in the environment. They are responsible for primary amoebic meningoencephalitis (PAM) and granulomatous amoebic encephalitis (GAE), the fatal ...
Siddiqui R +7 more
europepmc +2 more sources