Results 51 to 60 of about 891 (153)

Balamuthia mandrillaris - EBV Coinfective Encephalitis Diagnosed by MetaCAP: Comparative mNGS Validation and Epidemiological Landscape from 41 Chinese Cases.

International Journal of Infectious Diseases
OBJECTIVE This study aimed to present the first documented case of fatal granulomatous amoebic encephalitis (GAE) caused by Balamuthia mandrillaris and Epstein-Barr virus (EBV) co-infection, to evaluate the diagnostic performance of MetaCAP targeted ...
Ying Zhao, X. He, Zeping Han, Fengming Guo, Fangmei Xie, Shunzeng Lin, Liangjun Chen, Xiaoyu Song, Wenfeng Luo, Feifei Liu, Lei Zhang, Pingping Zhang, Zhiqiang Peng, Jinhua He   +13 more
semanticscholar   +1 more source

A patient with granulomatous amoebic encephalitis caused by Balamuthia mandrillaris survived with two excisions and medication

BMC Infectious Diseases, 2022
Background Granulomatous amoebic encephalitis (GAE) is a rare central nervous system infection caused by the Balamuthia mandrillaris or Acanthamoeba species.
L. Peng, Quan Zhou, Yu Wu, Xiaoli Cao, Z. Lv, M. Su, Yachun Yu, Wen Huang   +7 more
semanticscholar   +1 more source

Antiamoebic Properties of Laboratory and Clinically Used Drugs against Naegleria fowleri and Balamuthia mandrillaris

Antibiotics, 2022
Naegleria fowleri and Balamuthia mandrillaris are pathogenic free-living amoebae that infect the central nervous system with over 95% mortality rates.
Ruqaiyyah Siddiqui, Mohammad Ridwane Mungroo, Tengku Shahrul Anuar, Ahmad M. Alharbi, Hasan Alfahemi, Adel B. Elmoselhi, Naveed Ahmed Khan   +6 more
doaj   +1 more source

A Novel Protistan Trait Database Reveals Functional Redundancy and Complementarity in Terrestrial Protists (Amoebozoa and Rhizaria)

Molecular Ecology Resources, Volume 26, Issue 1, January 2026.
ABSTRACT The inclusion of functional traits of protists in environmental sequencing surveys, in addition to the traditional taxonomic framework, is essential for a better understanding of their roles and impacts on ecosystem processes. We provide a database of functional traits for a widespread and important clade of protists—the Amoebozoa—based on ...
Jule Freudenthal, Martin Schlegel, Michael Bonkowski, Kenneth Dumack   +3 more
wiley   +1 more source

Comparative neuropathology of Balamuthia mandrillaris infection across species

Parasitology
Balamuthia mandrillaris is a free-living amoeba that causes granulomatous amoebic encephalitis, a rare but frequently fatal infection of the central nervous system.
Ruqaiyyah Siddiqui, Sutherland Maciver, David Lloyd, Naveed Ahmed Khan   +3 more
doaj   +1 more source

Cyclic Peptide Natural Product Inspired Inhibitors of the Free-Living Amoeba Balamuthia mandrillaris

Journal of Natural Products
Balamuthia mandrillaris is a pathogenic free-living amoeba (pFLA) that can cause infection of the central nervous system (CNS), called Balamuthia amoebic encephalitis (BAE), as well as cutaneous and systemic diseases.
Chenyang Lu, Samantha Nelson, Gabriela Coy, Christopher Neumann, Elizabeth I. Parkinson, C. Rice   +5 more
semanticscholar   +1 more source

Amebic Encephalitis in a Patient with Chronic Lymphocytic Leukemia on Ibrutinib Therapy

Case Reports in Hematology, Volume 2018, Issue 1, 2018., 2018
Chronic lymphocytic leukemia (CLL) is the most common type of leukemia in Western countries. A common first‐line therapy offered to qualifying patients includes ibrutinib, an oral covalent inhibitor of Bruton’s tyrosine kinase. Treatment of CLL with ibrutinib therapy is generally well tolerated; however, serious opportunistic infections are being ...
Ensi Voshtina, Huiya Huang, Renju Raj, Ehab Atallah, Kiyotaka Kawauchi   +4 more
wiley   +1 more source

Isolation and identification of free-living amoeba from contact lenses: Thermal and osmotic tolerance in relation to their pathogenicity. [PDF]

Assiut University Journal of Multidisciplinary Scientific Research, 2022
Free-living amoeba (FLA) such as Acanthamoeba spp., Naegleria fowleri, Balamuthia mandrillaris, and Sappinia diploidea are widely distributed natural and human-made environments which may cause human diseases.  For example, N.
doaj   +1 more source

Drug susceptibility of a clinical isolate of Balamuthia mandrillaris, a pathogenic free-living amoeba

Antimicrobial Agents and Chemotherapy
Balamuthia amoebic encephalitis (BAE) is a highly fatal infection caused by Balamuthia mandrillaris, an amoeba that lives in soil and water. In Thailand, three fatal cases of BAE have been documented, but no survivors have been reported, raising ...
Pratima Dubey, Porntida Kobpornchai, Nongnat Tongkrajang, Suwipa Chaiyaloom, Chenyang Lu, C. Rice, Kasem Kulkeaw   +6 more
semanticscholar   +1 more source

In Vitro Activity of Nitroxoline (5‐Nitro‐8‐Hydroxyquinoline) Against Aspergillus Species

Mycoses, Volume 68, Issue 11, November 2025.
ABSTRACT Background Nitroxoline is an old antibiotic currently approved for the treatment of uncomplicated urinary tract infections. Its mode of action is based on the chelation of bivalent cations, such as zinc. Objectives As zinc plays a central role in the metabolism of Aspergillus spp., we performed antifungal susceptibility testing against ...
Ada Hoffmann, Oliver A. Cornely, Jana Vonhoegen, Rosanne Sprute, Ilana Reinhold, Grit Walther, Frieder Fuchs, Michaela Simon   +7 more
wiley   +1 more source