Results 51 to 60 of about 1,383 (171)

A clinical case report of Balamuthia granulomatous amoebic encephalitis in a non-immunocompromised patient and literature review

BMC Infectious Diseases, 2023
Background Balamuthia granulomatous amoebic encephalitis (GAE) is a peculiar parasitic infectious disease of the central nervous system, about 39% of the infected Balamuthia GAE patients were found to be immunocompromised and is extremely rare clinically.
Jun Liu, Wenjun Zhang, Shanlian Wu, Tianxiang Zeng, Fei Luo, Qiuhua Jiang, Ruijin Yang   +6 more
doaj   +1 more source

Microglia in neuropathology caused by protozoan parasites

Biological Reviews, Volume 95, Issue 2, Page 333-349, April 2020., 2020
ABSTRACT Involvement of the central nervous system (CNS) is the most severe consequence of some parasitic infections. Protozoal infections comprise a group of diseases that together affect billions of people worldwide and, according to the World Health Organization, are responsible for more than 500000 deaths annually. They include African and American
Katherine Figarella, Hartwig Wolburg, Olga Garaschuk, Michael Duszenko   +3 more
wiley   +1 more source

Disseminated Infection with Balamuthia mandrillaris in a Dog [PDF]

Veterinary Pathology, 2004
Bilateral chronic granulomatous nephritis and meningoencephalitis were diagnosed on necropsy of a 2-year-old male Great Dane dog. The causative agent was identified as Balamuthia mandrillaris, based on morphologic features, immunohistochemical staining, and deoxyribonucleic acid detection using the polymerase chain reaction with newly designed primer ...
O, Foreman, J, Sykes, L, Ball, N, Yang, H, De Cock   +4 more
openaire   +2 more sources

Balamuthia mandrillarisexhibits metalloprotease activities [PDF]

FEMS Immunology & Medical Microbiology, 2006
Balamuthia mandrillaris is a recently identified protozoan pathogen that can cause fatal granulomatous encephalitis. However, the pathogenesis and pathophysiology of B. mandrillaris encephalitis remain unclear. Because proteases may play a role in the central nervous system (CNS) pathology, we used spectrophotometric, cytopathic and zymographic assays ...
Abdul, Matin, Monique, Stins, Kwang Sik, Kim, Naveed Ahmed, Khan   +3 more
openaire   +2 more sources

First Draft Genome Sequence of Balamuthia mandrillaris, the Causative Agent of Amoebic Encephalitis [PDF]

, 2015
The free-living amoeba Balamuthia mandrillaris is a rare but highly lethal agent of amoebic encephalitis in humans and many other mammalian species. Here, we announce the first draft genome sequence of the original 1990 isolate cultured from the brain of
Detering, H., Radonić, Aleksandar, Nitsche, Andreas, Aebischer, Toni, Dabrowski, Piotr Wojtek, Renard, Bernhard Y., Kiderlen, Albrecht   +6 more
core   +1 more source

Emergence of Balamuthia mandrillaris meningoencephalitis in India

Indian Journal of Medical Microbiology, 2015
We report two cases of fatal chronic meningoencephalitis caused by Balamuthia mandrillaris in immunocompetent men. Diagnosis of amoebic meningoencephalitis was made ante-mortem in one case and postmortem in another by histopathological examination and confirmed by demonstration of B. mandrillaris deoxyribonucleic acid (DNA) by polymerase chain reaction
S, Khurana, V, Hallur, M K, Goyal, R, Sehgal, B D, Radotra   +4 more
openaire   +2 more sources

Molecular analysis unmasking a Balamuthia mandrillaris: Skin lesion and granulomatous amebic encephalitis by Acanthamoeba sp close to genotype T4 with fatal outcome

Clinical Infection in Practice
Background: Acanthamoeba sp, Balamuthia mandrillaris, are a free-living soil amoeba, has emerged as a causative agent of chronic GAE. Methods: The nasal biopsy was sent to our Laboratory of Pathogenic Protozoa and Endosymbionts (LPEP).
Alfonso Martín Cabello-Vílchez, M. Isabel Ruiz-Ruiz   +1 more
doaj   +1 more source

Transmission ofBalamuthia mandrillarisby Organ Transplantation [PDF]

Clinical Infectious Diseases, 2016
During 2009 and 2010, 2 clusters of organ transplant-transmitted Balamuthia mandrillaris, a free-living ameba, were detected by recognition of severe unexpected illness in multiple recipients from the same donor.We investigated all recipients and the 2 donors through interview, medical record review, and testing of available specimens retrospectively ...
Eileen C, Farnon, Kenneth E, Kokko, Philip J, Budge, Chukwuma, Mbaeyi, Emily C, Lutterloh, Yvonne, Qvarnstrom, Alexandre J, da Silva, Wun-Ju, Shieh, Sharon L, Roy, Christopher D, Paddock, Rama, Sriram, Sherif R, Zaki, Govinda S, Visvesvara, Matthew J, Kuehnert, Joli, Weiss, Ken, Komatsu, Richard, Manch, Alberto, Ramos, Leonor, Echeverria, Ann, Moore, Phil, Zakowski, Michelle, Kittleson, Jon, Kobashigawa, Jonathan, Yoder, Michael, Beach, William, Mahle, Kirk, Kanter, P J, Geraghty, Eileen, Navarro, Christine, Hahn, Shiro, Fujita, Jim, Stinson, Joel, Trachtenberg, Paul, Byers, Michele, Cheung, Tun, Jie, Bruce, Kaplan, Rainer, Gruessner, Erica, Bracamonte, Chad, Viscusi, Regino, Gonzalez-Peralta, Robert, Lawrence, Jonathan, Fratkin, Fauzia, Butt   +43 more
openaire   +2 more sources

Lethal encounters: The evolving spectrum of amoebic meningoencephalitis

IDCases, 2019
The free-living amoebae are thermophilic organisms that may play an increasing role among diseases of a warming world. They are uncommon, accidental, yet high consequence pathogens, with differing pathologic syndromes.
Sandra G. Gompf, Cristina Garcia
doaj   +1 more source

A devastating case of a Balamuthia mandrillaris pediatric brain infection. [PDF]

Radiol Case Rep
Balamuthia mandrillaris is an amoeba that causes an uncommon but deadly encephalitis, referred to as granulomatous amoebic encephalitis (GAE). The highest incidence reported worldwide has occurred in America, and within the United States, it has been highest in the Southwest affecting predominantly children and young men of Hispanic ethnicity. Clinical
Szymanski KA, Kuwabara MS, Friedman N, Pfeifer CM.   +3 more
europepmc   +4 more sources