Results 51 to 60 of about 493 (152)

Sequences and draft annotations of computationally predicted proteins from Balamuthia mandrillaris

, 2021
This file contains the sequences and draft annotations of computationally predicted proteins from Balamuthia mandrillaris. The sequences are reconstructed from RNA sequencing of logarithmic phase trophozoites, the infective form of the amoeba. Reads were
Phan, Isabelle Q., Noorai, Rooksana E., Tillery, Logan, Myler, Peter J., Barrett, Lynn K., Craig, Justin, Van Voorhis, Wesley C., Subramanian, Sandhya, Rice, Christopher A., Shankar, Vijay, Morris, James C., Kyle, Dennis E., McDonald, Jacquelyn R.   +12 more
core   +1 more source

A Novel Protistan Trait Database Reveals Functional Redundancy and Complementarity in Terrestrial Protists (Amoebozoa and Rhizaria)

Molecular Ecology Resources, Volume 26, Issue 1, January 2026.
ABSTRACT The inclusion of functional traits of protists in environmental sequencing surveys, in addition to the traditional taxonomic framework, is essential for a better understanding of their roles and impacts on ecosystem processes. We provide a database of functional traits for a widespread and important clade of protists—the Amoebozoa—based on ...
Jule Freudenthal, Martin Schlegel, Michael Bonkowski, Kenneth Dumack   +3 more
wiley   +1 more source

Comparative neuropathology of Balamuthia mandrillaris infection across species

Parasitology
Balamuthia mandrillaris is a free-living amoeba that causes granulomatous amoebic encephalitis, a rare but frequently fatal infection of the central nervous system.
Ruqaiyyah Siddiqui, Sutherland Maciver, David Lloyd, Naveed Ahmed Khan   +3 more
doaj   +1 more source

Amebic Encephalitis in a Patient with Chronic Lymphocytic Leukemia on Ibrutinib Therapy

Case Reports in Hematology, Volume 2018, Issue 1, 2018., 2018
Chronic lymphocytic leukemia (CLL) is the most common type of leukemia in Western countries. A common first‐line therapy offered to qualifying patients includes ibrutinib, an oral covalent inhibitor of Bruton’s tyrosine kinase. Treatment of CLL with ibrutinib therapy is generally well tolerated; however, serious opportunistic infections are being ...
Ensi Voshtina, Huiya Huang, Renju Raj, Ehab Atallah, Kiyotaka Kawauchi   +4 more
wiley   +1 more source

In Vitro Activity of Nitroxoline (5‐Nitro‐8‐Hydroxyquinoline) Against Aspergillus Species

Mycoses, Volume 68, Issue 11, November 2025.
ABSTRACT Background Nitroxoline is an old antibiotic currently approved for the treatment of uncomplicated urinary tract infections. Its mode of action is based on the chelation of bivalent cations, such as zinc. Objectives As zinc plays a central role in the metabolism of Aspergillus spp., we performed antifungal susceptibility testing against ...
Ada Hoffmann, Oliver A. Cornely, Jana Vonhoegen, Rosanne Sprute, Ilana Reinhold, Grit Walther, Frieder Fuchs, Michaela Simon   +7 more
wiley   +1 more source

Xenic Cultivation and Genotyping of Pathogenic Free‐Living Amoeba from Public Water Supply Sources in Uganda

New Journal of Science, Volume 2016, Issue 1, 2016., 2016
Studies on waterborne parasites from natural environment and domestic water sources in Uganda are very scarce and unpublished. Water dwelling free‐living amoebae (FLA) of the genus Acanthamoeba, Hartmannella, and Naegleria are often responsible for causing morbidities and mortalities in individuals with recent contact with contaminated water, but their
Celsus Sente, Joseph Erume, Irene Naigaga, Benigna Gabriela Namara, Julius Mulindwa, Sylvester Ochwo, Phillip Kimuda Magambo, Charles Drago Kato, Andrew Tamale, Michael Ocaido, Xinhua Shu   +10 more
wiley   +1 more source

Application of ventriculoscopy in granulomatous amoebic encephalitis: a case report in China and literature review

Frontiers in Medicine
Balamuthia mandrillaris is a kind of brain-eating amoeba leading to granulomatous amoebic encephalitis (GAE) with a high mortality rate and limited effective treatment options. Its underlying pathological mechanisms are still poorly understood.
Zequan Zheng, Zequan Zheng, Fajun Chen, Lulu Qin, Aili Lu, Haoyou Xu, Min Zhao, Yuanqi Zhao   +7 more
doaj   +1 more source

Discovery of repurposing drug candidates for the treatment of diseases caused by pathogenic free-living amoebae.

PLoS Neglected Tropical Diseases, 2020
Diseases caused by pathogenic free-living amoebae include primary amoebic meningoencephalitis (Naegleria fowleri), granulomatous amoebic encephalitis (Acanthamoeba spp.), Acanthamoeba keratitis, and Balamuthia amoebic encephalitis (Balamuthia ...
Christopher A Rice, Beatrice L Colon, Emily Chen, Mitchell V Hull, Dennis E Kyle   +4 more
doaj   +1 more source

Isolation and Environmental Detection of Balamuthia mandrillaris in Isfahan, Iran

Environmental Microbiology Reports, Volume 17, Issue 5, October 2025.
This study investigates the presence of Balamuthia mandrillaris in environmental sources from Isfahan, Iran, and compares cultural and molecular detection methods. The findings highlight matrix‐dependent detection patterns and report an overall prevalence of 15.6%.
Sara Lesani, Soroush Mirzania, Abbasali Eskandarian   +2 more
wiley   +1 more source

Stress Management in Cyst‐Forming Free‐Living Protists: Programmed Cell Death and/or Encystment

BioMed Research International, Volume 2015, Issue 1, 2015., 2015
In the face of harsh conditions and given a choice, a cell may (i) undergo programmed cell death, (ii) transform into a cancer cell, or (iii) enclose itself into a cyst form. In metazoans, the available evidence suggests that cellular machinery exists only to execute or avoid programmed cell death, while the ability to form a cyst was either lost or ...
Naveed Ahmed Khan, Junaid Iqbal, Ruqaiyyah Siddiqui, Philippe Holzmuller   +3 more
wiley   +1 more source