Pathogens, 2020 Pathogenic free-living amoebae, Balamuthia mandrillaris, Naegleria fowleri, and several Acanthamoeba species are the etiological agents of severe brain diseases, with case mortality rates > 90%.
Christopher A. Rice +3 more
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Diagnosing Balamuthia mandrillaris Encephalitis with Metagenomic Deep Sequencing [PDF]
, 2015 Objective Identification of a particular cause of meningoencephalitis can be challenging owing to the myriad bacteria, viruses, fungi, and parasites that can produce overlapping clinical phenotypes, frequently delaying diagnosis and therapy.
Wood, MD +13 more
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Balamuthia amoebic encephalitis directly causing intracranial infection: A case report
Radiology Case ReportsBalamuthia amoebic encephalitis (BAE) is a rare and often fatal central nervous system (CNS) infection caused by Balamuthia mandrillaris, a free-living amoeba typically found in soil and water. This organism can invade the brain directly, bypassing other
Yuhan Liang +5 more
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Granulomatous amebic encephalitis in a patient treated with chemotherapy: a case report and literature review [PDF]
Journal of Neurocritical CareBackground Granulomatous amebic encephalitis (GAE) is caused by Acanthamoeba species or Balamuthia mandrillaris, which are microscopic, free-living amoebas found worldwide. People with compromised immune systems are at an increased risk of fatal cerebral
Marcos R. Flores +4 more
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Influence of the Age of Free-Living Amoeba Cysts on Their Vertical Distribution in a Water Column
MicroorganismsFree-living amoebae (FLA) are widely distributed protozoa in both natural and artificial environments such as drinking water. In addition to the ability of all FLA to transport various pathogenic microorganisms, certain species, such as Acanthamoeba spp.
Zineb Fechtali-Moute, Sébastien Pomel
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, 2009 Balamuthia mandrillaris is a causative agent of granulomatous encephalitis that almost always proves fatal. A major concern during the course of therapy is that B. mandrillaris can transform into cysts. Cysts are highly resistant to physical and chemical
Siddiqui, R. +4 more
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The role of plasma metagenomic sequencing in identification of Balamuthia mandrillaris encephalitis
Acta Neuropathologica CommunicationsBalamuthia mandrillaris is a rare, free-living amoeba (FLA) that causes granulomatous amoebic encephalitis, a disease with close to 90% mortality. The geographical ranges of many FLA are expanding, potentially increasing human exposure to B. mandrillaris.
Sarah Y. Edminster +10 more
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Neurosurgical intervention in the diagnosis and treatment of Balamuthia mandrillaris encephalitis
, 2011 The authors describe the unique presentation of Balamuthia mandrillaris encephalitis in a kidney donor and two recipients. All three patients suffered acute clinical deterioration, with radiological or clinical evidence of intracranial hypertension ...
Marcus Lee +4 more
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Isolation of Acanthamoeba sp. y Balamuthia mandrillaris from commercial soil from a supermarket in Lima [PDF]
, 2021 Antecedentes: Los altos índices de letalidad en casos de infecciones humanas causadas por amebas de vida libre y su papel como reservorio de microorganismos patógenos ha impulsado su identificación en ambientes como la tierra.
Fernández Costilla, Fernando de Jesús +1 more
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Laboratory testing of clinically approved drugs against Balamuthia mandrillaris
, 2014 Balamuthia mandrillaris is a free-living protist pathogen that can cause life-threatening granulomatous amoebic encephalitis. Given the lack of effective available drugs against B.
Baig, Abdul Mannan +6 more
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