Results 71 to 80 of about 891 (153)

Modelling dynamics between free‐living amoebae and bacteria

Environmental Microbiology, Volume 26, Issue 5, May 2024.
This review scrutinizes mathematical models designed to simulate the interactions between free‐living amoebae and bacteria. Identified gaps encompass (1) the necessity to tackle complexities such as spatial heterogeneity and population diversity; and (2) the essential understanding of the system.
Marwa Ali, Christopher A. Rice, Andrew W. Byrne, Philip E. Paré, Wendy Beauvais   +4 more
wiley   +1 more source

Glucose metabolism in the pathogenic free‐living amoebae: Tempting targets for treatment development

Chemical Biology &Drug Design, Volume 103, Issue 1, January 2024.
Enzymes involved in glucose metabolism may be promising therapeutic targets for drug development against the pathogenic free‐living amoebae. Details about the enzyme sequence and structural properties make a compelling case for designing small molecule inhibitors that are specific to the amoebae and would not affect the host enzyme.AbstractPathogenic ...
Jillian E. Milanes, Samuel Kwain, Allyson Drawdy, Laura Dodson, Matthew T. Monaghan, Christopher A. Rice, Brian N. Dominy, Daniel C. Whitehead, James C. Morris   +8 more
wiley   +1 more source

Multiplex Real-Time Polymerase Chain Reaction Assay To Detect Acanthamoeba spp., Vermamoeba vermiformis, Naegleria fowleri, and Balamuthia mandrillaris in Different Water Sources.

American Journal of Tropical Medicine and Hygiene
Free-living amoebae (FLA) are widely distributed in the environment. Among these, Acanthamoeba spp., Naegleria fowleri, Balamuthia mandrillaris, and Vermamoeba vermiformis have been reported as human pathogens with health effects ranging from lethal ...
E. Córdoba-Lanús, M. Reyes-Batlle, A. Domínguez-de-Barros, Patricia Pérez-Pérez, R. Rodríguez-Expósito, Alma García-Ramos, I. Sifaoui, O. García-Pérez, Germán Aneiros-Giraldez, J. Piñero, Jacob Lorenzo-Morales   +10 more
semanticscholar   +1 more source

Balamuthia amoebic encephalitis directly causing intracranial infection: A case report

Radiology Case Reports
Balamuthia amoebic encephalitis (BAE) is a rare and often fatal central nervous system (CNS) infection caused by Balamuthia mandrillaris, a free-living amoeba typically found in soil and water. This organism can invade the brain directly, bypassing other
Yuhan Liang, Yanhong Liu, Zelong Chen, Jiayi Sun, Xuemeng Zhang, Yulin Wang   +5 more
doaj   +1 more source

Granulomatous amebic encephalitis in a patient treated with chemotherapy: a case report and literature review [PDF]

Journal of Neurocritical Care
Background Granulomatous amebic encephalitis (GAE) is caused by Acanthamoeba species or Balamuthia mandrillaris, which are microscopic, free-living amoebas found worldwide. People with compromised immune systems are at an increased risk of fatal cerebral
Marcos R. Flores, Miranda G. Montion, Aneesha N. Usman, Munachiso A. Ngene, Samir Ruxmohan   +4 more
doaj   +1 more source

Influence of the Age of Free-Living Amoeba Cysts on Their Vertical Distribution in a Water Column

Microorganisms
Free-living amoebae (FLA) are widely distributed protozoa in both natural and artificial environments such as drinking water. In addition to the ability of all FLA to transport various pathogenic microorganisms, certain species, such as Acanthamoeba spp.
Zineb Fechtali-Moute, Sébastien Pomel
doaj   +1 more source

Identification of Antigenic Targets for Immunodetection of Balamuthia mandrillaris Infection [PDF]

Clinical and Vaccine Immunology, 2011
ABSTRACTThe free-living amoebaBalamuthia mandrillariscauses granulomatous amoebic encephalitis (GAE) in humans. Rapid identification of balamuthiasis is critical for effective therapeutic intervention and case management. In the present study we identified target antigens for the development of a serological assay forB. mandrillarisinfection.
Zuzana, Kucerova, Rama, Sriram, Patricia P, Wilkins, Govinda S, Visvesvara   +3 more
openaire   +2 more sources

Detection of Balamuthia mandrillaris DNA by real-time PCR targeting the RNase P gene

BMC Microbiology, 2008
Background The free-living amoeba Balamuthia mandrillaris may cause fatal encephalitis both in immunocompromised and in – apparently – immunocompetent humans and other mammalian species. Rapid, specific, sensitive, and reliable detection requiring little
Lewin Astrid, Radam Elke, Kiderlen Albrecht F   +2 more
doaj   +1 more source

Discovery of Anti-Amoebic Inhibitors from Screening the MMV Pandemic Response Box on Balamuthia mandrillaris, Naegleria fowleri, and Acanthamoeba castellanii

Pathogens, 2020
Pathogenic free-living amoebae, Balamuthia mandrillaris, Naegleria fowleri, and several Acanthamoeba species are the etiological agents of severe brain diseases, with case mortality rates > 90%.
Christopher A. Rice, Emma V. Troth, A. Cassiopeia Russell, Dennis E. Kyle   +3 more
doaj   +1 more source

Non-granulomatous meningoencephalitis with Balamuthia mandrillaris mimicking a tumor: First confirmed case from Pakistan

Surgical neurology international
Background: Free-living amoebae rarely instigate intracranial infections that may resemble neoplastic conditions on imaging. Naegleria fowleri precipitates an acute, swiftly fatal meningoencephalitis, whereas Acanthamoeba and Balamuthia species typically
Zanibb Javed, Mustafa Mushtaq Hussain, Najia Ghanchi, Ahmed Gilani, S. Enam, MD Nancy E. Epstein   +5 more
semanticscholar   +1 more source