Results 71 to 80 of about 1,383 (171)

Rare Infectious Diseases: Detection and Clinical Implications

iLABMED, Volume 3, Issue 2, Page 148-157, June 2025.
Rare infectious diseases are infections that are uncommon, have a low incidence, and are caused by newly emerging pathogens, cross‐species or ectopic infections, or host immunodeficiencies. The detection and diagnosis of rare infections is one of the main reasons for misdiagnosis and missed diagnosis.
Xin Qian, Yuxin Zhang, Yilin Ye, Qiange Lin, Junyou Lin, Xinrong Lu, Li Chen, Guiqin Sun   +7 more
wiley   +1 more source

Clinical, Laboratory Characteristics, and Microorganism Infection Status in Neonates With Meningitis in Vietnam: A Cross‐Sectional Descriptive Study

International Journal of Pediatrics, Volume 2025, Issue 1, 2025.
Objective This study is aimed at describing the clinical and laboratory characteristics and determining the prevalence of microbial pathogens causing neonatal meningitis detected by cerebrospinal fluid (CSF) real‐time polymerase chain reaction (PCR). Materials and Methods A cross‐sectional descriptive study was conducted on 55 neonates diagnosed with ...
Tho Kieu Anh Pham, Binh Thien Nguyen, Phuong Minh Nguyen, Khai Quang Tran, Nikhat Kaura   +4 more
wiley   +1 more source

Encephalomyelomeningitis Caused by Balamuthia mandrillaris: A Case Report and Literature Review

Infection and Drug Resistance, 2023
XueMei Fan,1 TianWen Chen,1 Hui Yang,1 Yue Gao,2,* Yan Chen1,* 1Department of Neurology, Affiliated Hangzhou First People’s Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, People’s Republic of China; 2Department of General ...
Fan X, Chen T, Yang H, Gao Y, Chen Y
doaj  

Modelling dynamics between free‐living amoebae and bacteria

Environmental Microbiology, Volume 26, Issue 5, May 2024.
This review scrutinizes mathematical models designed to simulate the interactions between free‐living amoebae and bacteria. Identified gaps encompass (1) the necessity to tackle complexities such as spatial heterogeneity and population diversity; and (2) the essential understanding of the system.
Marwa Ali, Christopher A. Rice, Andrew W. Byrne, Philip E. Paré, Wendy Beauvais   +4 more
wiley   +1 more source

Glucose metabolism in the pathogenic free‐living amoebae: Tempting targets for treatment development

Chemical Biology &Drug Design, Volume 103, Issue 1, January 2024.
Enzymes involved in glucose metabolism may be promising therapeutic targets for drug development against the pathogenic free‐living amoebae. Details about the enzyme sequence and structural properties make a compelling case for designing small molecule inhibitors that are specific to the amoebae and would not affect the host enzyme.AbstractPathogenic ...
Jillian E. Milanes, Samuel Kwain, Allyson Drawdy, Laura Dodson, Matthew T. Monaghan, Christopher A. Rice, Brian N. Dominy, Daniel C. Whitehead, James C. Morris   +8 more
wiley   +1 more source

Novel Azoles as Antiparasitic Remedies against Brain-Eating Amoebae

Antibiotics, 2020
Balamuthia mandrillaris and Naegleria fowleri are opportunistic protozoan pathogens capable of producing infection of the central nervous system with more than 95% mortality rate.
Ayaz Anwar, Mohammad Ridwane Mungroo, Simal Khan, Itrat Fatima, Rafaila Rafique, Kanwal, Khalid Mohammed Khan, Ruqaiyyah Siddiqui, Naveed Ahmed Khan   +8 more
doaj   +1 more source

Serum antibodies to Balamuthia mandrillaris, a free-living amoeba recently demonstrated to cause granulomatous amoebic encephalitis [PDF]

, 1999
© 1999 by the Infectious Diseases Society of America. All rights reserved.Free-living amoebae cause three well-defined disease entities: a rapidly fatal primary meningoencephalitis, a chronic granulomatous amoebic encephalitis (GAE), and a chronic ...
Ferrante, A., Carter, R., Huang, Z.
core   +1 more source

Sequences and draft annotations of computationally predicted proteins from Balamuthia mandrillaris

, 2021
This file contains the sequences and draft annotations of computationally predicted proteins from Balamuthia mandrillaris. The sequences are reconstructed from RNA sequencing of logarithmic phase trophozoites, the infective form of the amoeba. Reads were
Phan, Isabelle Q., Noorai, Rooksana E., Tillery, Logan, Myler, Peter J., Barrett, Lynn K., Craig, Justin, Van Voorhis, Wesley C., Subramanian, Sandhya, Rice, Christopher A., Shankar, Vijay, Morris, James C., Kyle, Dennis E., McDonald, Jacquelyn R.   +12 more
core   +1 more source

Isolation and molecular characterization of Acanthamoeba and Balamuthia mandrillaris from combination shower units in Costa Rica

, 2014
Free living amoebae (FLA) are ubiquitous protozoa, which may behave as parasites under certain conditions. Four genera are recognized as causal agents of infections in humans and animals: Naegleria, Sappinia, Acanthamoeba and Balamuthia.
Reyes Batlle, María, Valladares Hernández, Basilio, Piñero Barroso, José Enrique, Abrahams Sandí, Elizabeth, Cabello Vílchez, Alfonso Martín, Martínez Carretero, Enrique, Lorenzo Morales, Jacob, Retana Moreira, Lissette   +7 more
core   +1 more source

Effect of antimicrobial compounds on Balamuthia mandrillaris encystment and human brain microvascular endothelial cell cytopathogenicity.

, 2007
Cycloheximide, ketoconazole, or preexposure of organisms to cytochalasin D prevented Balamuthia mandrillaris-associated cytopathogenicity in human brain microvascular endothelial cells, which constitute the blood-brain barrier. In an assay for inhibition
Siddiqui, Ruqaiyyah, Khan, Naveed Ahmed, Warhurst, David, Stins, Monique, Matin, Abdul   +4 more
core   +1 more source