Results 81 to 90 of about 3,235,049 (345)
A stepwise emergence of evolution in the RNA world
FEBS Letters, EarlyView.How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley +1 more source
Frontiers in NeurologyBackgroundThis study systematically evaluated the effects of virtual reality training (VRT) on balance ability and functional gait in Parkinson’s disease (PD) patients and used dose–response analysis to quantify optimal intervention parameters, providing
Hailong Wu, Cheng Zhang
doaj +1 more source
Evolutionary interplay between viruses and R‐loops
FEBS Letters, EarlyView.Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi +4 more
wiley +1 more source
Everyone’s a Critic: Defamation and Anonymity on the Internet [PDF]
, 2002 Internet publishing is easy and has become commonplace in ourtechnology-focused society. Although this type of publication can beexciting and helpful for those interested in communicating an idea, theissue of anonymous speech on the Internet has created ...
Stiles, Allison
core +1 more source
Quantitative Measures of a Robot's Ability to Balance
Robotics: Science and Systems XI, 2015 This paper shows how to define quantitative measures of a robot’s ability to balance itself actively on a single point of support. These measures are expressed as ratios of velocities, and are called velocity gains. This paper builds on earlier work in this area by showing how these gains can be defined and calculated for the case of a general planar ...
openaire +2 more sources
Relationship between Walking Ability and Balance Function
The Japanese Journal of Rehabilitation Medicine, 2006 バランス機能は歩行能力に影響する因子の一つと考えられる．そこで歩行能力の代表的な評価法である最大歩行速度 (Maximum Walking Speed: MWS) と各種バランス検査を，若年者群と高齢者群で検討した．身長は若年者群ではMWS, Functional reach (FR)，タンデム肢位での重心動揺，Timed Up and Go test (TUG) と相関したが，高齢者群では関係は認められなかった．若年者群ではMWSは，タンデム肢位外周面積，TUGと相関したが，これは身長の影響によると考えられた．高齢者群ではMWSは，FR，タンデム肢位総軌跡長，TUGと相関した．高齢者では歩行能力は静的・動的両者のバランス機能に影響されることが示唆された．
Satoshi Miyano +2 more
openaire +3 more sources
Cyclic nucleotide signaling as a drug target in retinitis pigmentosa
FEBS Letters, EarlyView.Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää +2 more
wiley +1 more source
, 2006 Philanthropy's primary funding strategy -- restricted grants -- too often hamstrings grantees' ability to plan, invest, and respond to changes with vision, flexibility, and innovation. Since its inception, the F.B.
John Weiler
core
Targeting self-renewal pathways in myeloid malignancies [PDF]
, 2013 A fundamental property of hematopoietic stem cells (HSCs) is the ability to self-renew. This is a complex process involving multiple signal transduction cascades which control the fine balance between self-renewal and differentiation through ...
Copland, M., Sands, W.A., Wheadon, H.
core +2 more sources
FEBS Letters, EarlyView.Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu +17 more
wiley +1 more source