Results 41 to 50 of about 1,118,137 (291)

Circular designs balanced for neighbours at distances one and two [PDF]

open access: yes, 2014
Date of Acceptance: 23/05/2014We define three types of neighbour-balanced designs for experiments where the units are arranged in a circle or single line in space or time.
Aldred, R E L   +7 more
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Análise da eficiência do Balanced Scorecard: multi estudos de caso em organizações do Balanced Scorecard Hall os Fame [PDF]

open access: yes, 2009
TCC (graduação) - Universidade Federal de Santa Catarina, Centro Sócio Econômico, Curso de Administração.O presente estudo tem como objetivo analisar a eficiência do balanced scorecard como ferramenta de gestão estratégica integrada em duas organizações ...
Bento, Marcos Vinícius Tedrus Cezar
core  

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

A Student’s T Mixture Cardinality-Balanced Multi-Target Multi-Bernoulli Filter With Heavy-Tailed Process and Measurement Noises

open access: yesIEEE Access, 2018
The cardinality-balanced multi-target multi-Bernoulli (CBMeMBer) filter is a promising solution for multi-target tracking. However, the performance of the CBMeMBer filter will be degraded severely by outliers in the presence of heavy-tailed process noise
Mingjie Wang   +3 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

On Modelling of Balanced Filters

open access: yes2024 IEEE International Microwave Filter Workshop (IMFW)
In this paper, a lattice-based model of balanced filters is proposed. The symmetric lattice model is derived directly from the transversal circuit model of coupled-resonators filters through a series of equivalent transformations. Expressions for S-parameters of general symmetric lattice network are derived, as well as equations for S-parameters of ...
Glubokov, Oleksandr   +4 more
openaire   +2 more sources

High common‐mode suppression balanced bandpass filter using isosceles right‐angled triangular resonator

open access: yesElectronics Letters, 2019
A balanced bandpass filter with high common‐mode (CM) suppression using isosceles right‐angled triangular (RAT) resonator is proposed in this Letter. The two high order orthogonal modes (TM210Z and TM200Z) are generated in the two overlapped isosceles ...
Qiao Zhang, Chang Chen, Weidong Chen
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

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