Results 51 to 60 of about 603 (213)

Sigma Delta Modulation Based Ternary FIR Filter Mapping on FPGA [PDF]

open access: yesMehran University Research Journal of Engineering and Technology, 2011
In this paper single-bit SDM (Sigma Delta Modulation) based TFF (Ternary FIR Filter) with balanced ternary coefficients (i.e. -1/0/+1) has been mapped on small commercially available FPGAs (Field Programmable Gate Arrays).
Tayabuddin Memon   +2 more
doaj  

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Servo Control of Shunt-Active Power Filters Using Kalman Filter With DC-Link Reference [PDF]

open access: yesE3S Web of Conferences
LQG servo controllers may regulate current flow in a SAPF (shunt-active power filter) provided by a balanced or unbalanced supply voltage. Balanced or uneven supply voltages power the SAPF.
Vijay Kumar C. V.   +5 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

High Selective Balanced Bandpass Filters Using End-Connected Conductor-Backed Coplanar Waveguide

open access: yesIEEE Access, 2019
In this paper, an end-connected conductor-backed coplanar waveguide (CBCPW) balanced bandpass filter and a size reduction one with adjustable multiple transmission zeros have been developed by using the separated electric and magnetic coupling, and ...
Jian-Kang Xiao   +3 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Improved multi-target tracking algorithm based on SMC-CBMeMBer for the airborne Doppler radar

open access: yesThe Journal of Engineering, 2019
To effectively suppress clutter in airborne Doppler radar and improve multi-target tracking (MTT) performance, this study proposes an improved MTT algorithm based on Sequential Monte Carlo Cardinality Balanced Multi-target Multi-Bernoulli (SMC-CBMeMBer ...
Muyang Luo   +4 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

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