Results 51 to 60 of about 1,118,137 (291)

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Stein-Rule Estimation under an Extended Balanced Loss Function [PDF]

open access: yes, 2007
This paper extends the balanced loss function to a more general set up. The ordinary least squares and Stein-rule estimators are exposed to this general loss function with quadratic loss structure in a linear regression model.
Toutenburg, Helge   +3 more
core   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

Balanced Filtering via Disclosure-Controlled Proxies

open access: yes, 2023
We study the problem of collecting a cohort or set that is balanced with respect to sensitive groups when group membership is unavailable or prohibited from use at deployment time. Specifically, our deployment-time collection mechanism does not reveal significantly more about the group membership of any individual sample than can be ascertained from ...
Deng, Siqi   +3 more
openaire   +5 more sources

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Servo Control of Shunt-Active Power Filters Using Kalman Filter With DC-Link Reference [PDF]

open access: yesE3S Web of Conferences
LQG servo controllers may regulate current flow in a SAPF (shunt-active power filter) provided by a balanced or unbalanced supply voltage. Balanced or uneven supply voltages power the SAPF.
Vijay Kumar C. V.   +5 more
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Sigma Delta Modulation Based Ternary FIR Filter Mapping on FPGA [PDF]

open access: yesMehran University Research Journal of Engineering and Technology, 2011
In this paper single-bit SDM (Sigma Delta Modulation) based TFF (Ternary FIR Filter) with balanced ternary coefficients (i.e. -1/0/+1) has been mapped on small commercially available FPGAs (Field Programmable Gate Arrays).
Tayabuddin Memon   +2 more
doaj  

Home - About - Disclaimer - Privacy