Results 71 to 80 of about 1,737,261 (319)

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

Deep Learning Nonhomogeneous Elliptic Interface Problems by Soft Constraint Physics-Informed Neural Networks

open access: yesMathematics, 2023
It is a great challenge to solve nonhomogeneous elliptic interface problems, because the interface divides the computational domain into two disjoint parts, and the solution may change dramatically across the interface. A soft constraint physics-informed
Fujun Cao   +3 more
doaj   +1 more source

Itinerant ferromagnetism in an interacting Fermi gas with mass imbalance

open access: yes, 2011
We study the emergence of itinerant ferromagnetism in an ultra-cold atomic gas with a variable mass ratio between the up and down spin species. Mass imbalance breaks the SU(2) spin symmetry leading to a modified Stoner criterion.
A. I. Larkin   +3 more
core   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

A new approach for shrinkage estimators of the multivariate normal mean vector under the balanced loss criterion

open access: yesFrontiers in Applied Mathematics and Statistics
In this study, we investigate the issue of estimating the mean vector of a multivariate normal distribution. We introduce two new families of shrinkage estimators derived from both the maximum likelihood estimator and the James-Stein estimator.
Najla M. ALoraini   +2 more
doaj   +1 more source

Deep Supervised Hashing for Fast Multi-Label Image

open access: yesMATEC Web of Conferences, 2018
In this paper, most of the existing Hashing methods is mapping the hand extracted features to binary code, and designing the loss function with the label of images.
Ying Qian, Qingqing Ye
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Meta-Optimization of Bias-Variance Trade-Off in Stochastic Model Learning

open access: yesIEEE Access, 2021
Model-based reinforcement learning is expected to be a method that can safely acquire the optimal policy under real-world conditions by using a stochastic dynamics model for planning.
Takumi Aotani   +2 more
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Security of quantum cryptography using balanced homodyne detection

open access: yes, 2003
In this paper we investigate the security of a quantum cryptographic scheme which utilizes balanced homodyne detection and weak coherent pulse (WCP).
A.K. Ekert   +25 more
core   +1 more source

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