Results 111 to 120 of about 587,507 (249)
A ponderação de regras e alguns problemas da teoria dos princípios de Robert Alexy
Revista Direito GVResumo Este artigo versa sobre a distinção entre regras e princípios e analisa alguns aspectos da difundida tese da distinção qualitativa sustentada por Ronald Dworkin e Robert Alexy.
Bruno Sacramento Santos Silva
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Heuristic methods for cost-oriented assembly line balancing: a survey [PDF]
This paper is concerned with cost-oriented assembly line balancing. This problem occurs especially in the final assembly of automotives, consumer durables or personal computers, where production is still very labour- intensive, and where the wage rates ...
Matthias Amen
core
BALANCING OF ROTORS WITH HINGED WORKING PARTS
Advanced Engineering Research, 2011 Generalized rational technology of the rotors with hinged working parts is developed. Their balancing speed is a priori established, that enables to formalize the technological preparation of those rotors balancing.
Oleg O. Polushkin +2 more
doaj
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
AN EMPIRICAL INVESTIGATION ON THE SUSTAINABILITY OF BALANCING ITEM OF BALANCE OF PAYMENT ACCOUNTS FOR OIC MEMBER COUNTRIES [PDF]
This study aims to examine the sustainability of balancing item (???net errors and omissions') of balance of payment accounts for OIC (Organisation of the Islamic Conference) member countries.
Tuck Cheong Tang, Evan Lau
core
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Changing Balancing Behaviors in Turkish Foreign Policy During AKP Period (2002-2019)
Gazi Akademik Bakış, 2019 States’ foreign policies and their strategies to attain them are not fixed. When international and domestic dynamics change, policies and strategies may change.
Oktay BİNGÖL
doaj