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Balkan (Endemic) Nephropathy

2015
The clinical and pathological features of Balkan (endemic) nephropathy are discussed and correlations of incidence with excess late summer and autumn rainfall outlined. Cultures of a strain of Penicillium verrucosum var. cyclopium isolated from maize collected in an endemic area were fed to rats and lesions were produced in the straight third segment ...
P K, Austwick   +4 more
semanticscholar   +4 more sources

Effects of Diet on Aristolochic Acid-DNA Adduct Formation: Implications for Balkan Endemic Nephropathy Etiology.

Chemical Research in Toxicology, 2023
Prolonged exposure to aristolochic acids (AAs) through AA-containing herbal medicine or AA-contaminated food is associated with the development of aristolochic acid nephropathy (AAN) and Balkan endemic nephropathy (BEN), both public health risks to which
Jiayin Zhang   +3 more
semanticscholar   +1 more source

Synergistic Interaction of Polycyclic Aromatic Hydrocarbons, Phthalate Esters, or Phenol on DNA Adduct Formation by Aristolochic Acid I: Insights into the Etiology of Balkan Endemic Nephropathy.

Chemical Research in Toxicology, 2022
Balkan endemic nephropathy (BEN) is a multifactorial environmental disease, with chronic exposure to aristolochic acids (AAs) through AA-contaminated food being one of the major etiological mechanisms.
Jiayin Zhang, K. Chan, W. Chan
semanticscholar   +1 more source

Analysis of Polycyclic Aromatic Hydrocarbons and Phthalate Esters in Soil and Food Grains from the Balkan Peninsula: Implication on DNA Adduct Formation by Aristolochic Acid I and Balkan Endemic Nephropathy.

Environmental Science and Technology, 2021
Balkan endemic nephropathy (BEN) is a chronic tubulointerstitial nephropathy affecting residents of rural farming areas in many Balkan countries. Although it is generally believed that BEN is an environmental disease caused by multiple geochemical ...
Wan-hua Guo   +8 more
semanticscholar   +1 more source

Balkan Endemic Nephropathy and the Causative Role of Aristolochic Acid

open access: yesSeminars in Nephrology, 2019
Bojan Jelaković   +2 more
exaly   +2 more sources

Determination of Aristolochic Acids in Vegetables: Nephrotoxic and Carcinogenic Environmental Pollutants Contaminating a Broad Swath of the Food Supply and Driving Incidence of Balkan Endemic Nephropathy.

Chemical Research in Toxicology, 2020
Balkan endemic nephropathy (BEN) is a slowly progressive interstitial fibrotic disease affecting numerous people living along the Danube River in the Balkan Peninsula, of which aristolochic acids (AAs) produced naturally in Aristolochia plants are key ...
Chun-Kit Au   +7 more
semanticscholar   +1 more source

Pathomorphology of Balkan endemic nephropathy

Food and Chemical Toxicology, 1992
Within the county of Slavonski Brod, Yugoslavia hyperendemic areas of Balkan endemic nephropathy (BEN) have been recognized for a long time. As the Department of Pathology and Forensic Medicine of the Medical Centre in Slavonski Brod is responsible for all diagnostic post-mortem examinations in the county, and at the same time is engaged in surgical ...
M, Vukelić, B, Sostarić, M, Belicza
openaire   +2 more sources

Epidemiology of Balkan endemic nephropathy

Food and Chemical Toxicology, 1992
The first outbreak of Balkan endemic nephropathy (BEN) was reported between 1955 and 1957, initially in Serbia and soon afterwards in Croatia and in Bosnia and Herzegovina. The disease appears to be of a focal nature. In Yugoslavia at least six foci are known, generally along major rivers of the Danubian river basin, in areas that have often been ...
S, Ceović, A, Hrabar, M, Sarić
openaire   +2 more sources

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