Results 21 to 30 of about 1,591 (203)

Detection and Removal of Aristolochic Acid in Natural Plants, Pharmaceuticals, and Environmental and Biological Samples: A Review

Molecules, 2023
Aristolochic acids (AAs) are a toxic substance present in certain natural plants. Direct human exposure to these plants containing AAs leads to a severe and irreversible condition known as aristolochic acid nephropathy (AAN).
Changhong Wang, Yunchao Liu, Jintai Han, Wenying Li, Jing Sun, Yinan Wang   +5 more
doaj   +1 more source

Programmed cell death in sepsis in Balkan nephropathy [PDF]

Vojnosanitetski Pregled, 2013
nema
Savin Marina
doaj   +1 more source

Inaccuracy of Ureteroscopic Biopsy in Upper Tract Urothelial Carcinoma Can Lead to False Therapeutic Decisions: A Case Report. [PDF]

Clin Case Rep
ABSTRACT Do not rely solely on negative endoscopic biopsies when diagnosing upper tract urothelial carcinoma (UTUC). Repeat ureteroscopy with biopsy if initial results are negative to reduce false negatives. Frozen section analysis (FSA) can provide rapid intraoperative confirmation and guide treatment decisions.
Hidayat-Allah A, Friedersdorff F.
europepmc   +2 more sources

The Concise Guide to PHARMACOLOGY 2023/24: Ion channels

British Journal of Pharmacology, Volume 180, Issue S2, Page S145-S222, October 2023., 2023
The Concise Guide to PHARMACOLOGY 2023/24 is the sixth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of approximately 1800 drug targets, and over 6000 interactions with about 3900 ligands. There is an emphasis on selective pharmacology (where available), plus links
Stephen P. H. Alexander, Alistair A. Mathie, John A. Peters, Emma L. Veale, Jörg Striessnig, Eamonn Kelly, Jane F. Armstrong, Elena Faccenda, Simon D. Harding, Jamie A. Davies, Richard W. Aldrich, Bernard Attali, Austin M. Baggetta, Elvir Becirovic, Martin Biel, Roslyn M. Bill, Ana I. Caceres, William A. Catterall, Alex C. Conner, Paul Davies, Katrien De Clerq, Markus Delling, Francesco Di Virgilio, Simonetta Falzoni, Stefanie Fenske, Anna Fortuny‐Gomez, Samuel Fountain, Chandy George, Steve A. N. Goldstein, Christian Grimm, Stephan Grissmer, Kotdaji Ha, Verena Hammelmann, Israel Hanukoglu, Meiqin Hu, Ad P. Ijzerman, Sairam V. Jabba, Mike Jarvis, Anders A. Jensen, Sven E. Jordt, Leonard K. Kaczmarek, Stephan Kellenberger, Charles Kennedy, Brian King, Philip Kitchen, Qiang Liu, Joseph W. Lynch, Jessica Meades, Verena Mehlfeld, Annette Nicke, Stefan Offermanns, Edward Perez‐Reyes, Leigh D. Plant, Lachlan Rash, Dejian Ren, Mootaz M. Salman, Werner Sieghart, Lucia G. Sivilotti, Trevor G. Smart, Terrance P. Snutch, Jinbin Tian, James S. Trimmer, Charlotte Van den Eynde, Joris Vriens, Aguan D. Wei, Brenda T. Winn, Heike Wulff, Haoxing Xu, Fan Yang, Wei Fang, Lixia Yue, Xiaoli Zhang, Michael Zhu   +72 more
wiley   +1 more source

Prognostic value of p53, c-ErbB2 and tunel data in upper urothelial carcinoma associated with Balkan nephropathy [PDF]

Archives of Biological Sciences, 2014
A characteristic tumor suppressor protein 53 (p53) mutational profile of genotoxic action of aristolochic acid was identified in the upper urothelial carcinoma (UUTT) associated with Balkan nephropathy (BEN).
Savin Marina, Džamić Z., Baralić M., Radojević-Škodrić Sanja, Marinković Jelena, Bumbaširević V.   +5 more
doaj   +1 more source

Ochratoxin A: In Utero Exposure in Mice Induces Adducts in Testicular DNA [PDF]

, 2010
Ochratoxin A (OTA) is a nephrotoxin and carcinogen that is associated with Balkan endemic nephropathy and urinary tract tumors. OTA crosses the placenta and causes adducts in the liver and kidney DNA of newborns.
Jennings-Gee, Jamie E., Mark Steven Miller, Tozlovanu, Mariana, Jamie E. Jennings-Gee, Mariana Tozlovanu, Miller, Mark Steven, Annie Pfohl-Leszkowicz, Gary G. Schwartz, Schwartz, Gary G., Manderville, Richard A., Pfohl-Leszkowicz, Annie, Richard Manderville   +11 more
core   +1 more source

Clinical findings and kidney morphology in chronic kidney disease of unknown cause in India

Journal of Internal Medicine, Volume 294, Issue 4, Page 492-505, October 2023., 2023
Abstract Background Chronic kidney disease of unknown cause (CKDu) is an emerging health problem in India and other countries worldwide. However, clinical descriptions, including kidney pathology, are scarce. Methods This is a descriptive case series of patients with CKDu from an endemic region in India, with a focus on clinical and biochemical ...
Julia Wijkström, Kumar Chakravarthy Annadata, Carl‐Gustaf Elinder, Praveen Kumar Kolla, Narayana Rao Sarvepalli, Anneli Ring, Rajendiran Swaminathan, Barathi Gunabooshanam, Magnus Söderberg, Vidhya Venugopal, Annika Wernerson   +10 more
wiley   +1 more source

Tamm-Horsfall Protein in Balkan Endemic Nephropathy [PDF]

, 1984
Summary: It is suggested that Tamm-Horsfall protein, a specific renal glycoprotein, may be involved in the pathogenesis of some renal diseases. In cadmium nephropathy and Fanconi syndrome (primary tubular diseases of the kidney) an increased excretion ...
Stavljenić, Ana, Čvorišćec, Dubravka, Ana Stavljenic, Radonić, M., Dubravka Cvoriscec, M. Radonic   +5 more
core   +1 more source

Chronic kidney disease of unknown aetiology: A comprehensive review of a global public health problem

Tropical Medicine &International Health, Volume 28, Issue 8, Page 588-600, August 2023., 2023
Abstract The term chronic kidney disease of unknown aetiology (CKDu) refers to chronic kidney disease (CKD) in the absence of diabetes, long‐standing hypertension, glomerulonephritis, obstructive uropathy or other apparent causes. An increasing number of CKDu cases have been reported from Latin America, Sri Lanka, India and others over the last two ...
Indu Ramachandra Rao, Ashika Bangera, Shankar Prasad Nagaraju, Srinivas Vinayak Shenoy, Ravindra Attur Prabhu, Dharshan Rangaswamy, Mohan Varadanayakanahalli Bhojaraja   +6 more
wiley   +1 more source

Acute Kidney Injury Following the Ingestion of a Medicinal Plants' Mixture: A Case Report. [PDF]

Case Rep Nephrol
Acute renal failure secondary to medicinal plants is common in countries where the use of traditional phytotherapy is preponderant. Although the nephrotoxic potentials of some herbal preparations have been well characterized, the use of many medicinal plants is still considered largely safe, often relying on weak evidence. Here, we report the case of a
Selles A, Afir Y, Rahou Y, Debchi L, Rafa-Debbah H, Bahriz MR, Benziane A.   +6 more
europepmc   +2 more sources