Results 61 to 70 of about 1,591 (203)

The Concise Guide to PHARMACOLOGY 2025/26: Ion channels

British Journal of Pharmacology, Volume 182, Issue S1, Page S152-S241, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander, Jörg Striessnig, Alasdair J. Gibb, Alistair A. Mathie, Emma L. Veale, Eamonn Kelly, Chloe J. Peach, Jane F. Armstrong, Elena Faccenda, Simon D. Harding, Christopher Southan, Jamie A. Davies, Richard W. Aldrich, Bernard Attali, Austin M. Baggetta, Elvir Becirovic, David J. Beech, Martin Biel, Roslyn M. Bill, Ana I. Caceres, William A. Catterall, Han Chow Chua, Alex C. Conner, Henry Danahay, Paul Davies, Katrien De Clerq, Markus Delling, Francesco Di Virgilio, Simonetta Falzoni, Wei Fang, Stefanie Fenske, Anna Fortuny‐Gomez, Samuel Fountain, George K. Chandy, Mohammad‐Reza Ghovanloo, Steve A. N. Goldstein, Martin Gosling, Christian Grimm, Stephan Grissmer, Kotdaji Ha, Tim G. Hales, Verena Hammelmann, Israel Hanukoglu, Meiqin Hu, Ad P. Ijzerman, Sairam V. Jabba, Mike Jarvis, Anders A. Jensen, Sven E. Jordt, Leonard K. Kaczmarek, Stephan Kellenberger, Charles Kennedy, Brian King, Philip Kitchen, Qiang Liu, Joseph W. Lynch, Rian W. Manville, Jessica Meades, Verena Mehlfeld, Annette Nicke, Stefan Offermanns, Edward Pérez‐Reyes, Leigh D. Plant, Stephan A. Pless, Lachlan D. Rash, Dejian Ren, Hussein N. Rubaiy, Mootaz M. Salman, Werner Sieghart, Lucia G. Sivilotti, Trevor G. Smart, Terrance P. Snutch, Paolo Tammaro, Jinbin Tian, James S. Trimmer, Charlotte Van den Eynde, Paola Vergani, Joris Vriens, Stephen G. Waxman, Aguan D. Wei, Brenda T. Winn, Heike Wulff, Haoxing Xu, Fan Yang, Lixia Yue, Xiaoli Zhang, Michael Zhu   +86 more
wiley   +1 more source

Balkan Endemic Nephropathy Risk Associates to the hs1.2 Ig Enhancer Polymorphism

European Journal of Inflammation, 2012
Balkan Endemic Nephropathy (BEN) is a kidney degenerative disease with a high incidence in the valleys of the Danube and tributary rivers. Many studies describe it as a multifactorial disease.
D. Frezza, E. Serone, S. Lolli, R. Cianci, P. D'Addabbo, C. Mattioli, V. Giambra, N. Pavlovic, V. Djordjevic, S. Kostic, F. Pandolfi, E. Kostic   +11 more
doaj   +1 more source

Fifty years of Balkan endemic nephropathy: daunting questions, elusive answers

, 2006
Balkan endemic nephropathy (BEN) has remained a geographically constant endemic for 50 years. Despite extensive research, its etiology remains unknown. In the current issue, in a study in one of the earliest sites where the endemic was first recognized ...
Batuman, V., V. Batuman
core   +1 more source

Development of ion trap HPLC-MS detection methods for the determination of prevalent mycotoxins in grain and application to real samples [PDF]

, 2007
The prevalent trichothecenes deoxynivalenol, nivalenol and HT-2 as well as zearalenone, zearalenol, ochratoxin A and citrinin are typical widespread mycotoxins in temperate climate zones mainly produced by the genus Fusarium, Aspergillus and Penicillium.
Griesshaber, Dorrit Suenja
core   +1 more source

Aspergillus Mycotoxins: The Major Food Contaminants

Advanced Science, Volume 12, Issue 9, March 6, 2025.
Mycotoxins produced by Aspergillus contaminate food products and threat to human health. The multifaceted biosynthesis pathways are first discussed and elucidated several global regulators of the mycotoxins in detail. How global shifts in temperature and water availability, driven by climate change, are key determinants of Aspergillus proliferation and
Mengyao Xue, Zheng Qu, Antonio Moretti, Antonio F. Logrieco, Haiyan Chu, Qi Zhang, Changpo Sun, Xianfeng Ren, Li Cui, Qinglin Chen, Yi An, Chengjun Li, Huan Zhong, Zhiyan Cao, Feng Wang, Yuebing Sun, Lili Wang, Jie Hou, Chenchen Zhang, Mengmeng Yang, Yiming Ding, Yanpo Yao, Peiwu Li, Yong‐Guan Zhu   +23 more
wiley   +1 more source

The Role of Inflammation, Oxidative Stress, Neuronal Damage, and Endothelial Dysfunction in the Neuropathology of Cognitive Complications in Diabetes: A Moderation and Mediation Analysis

Brain and Behavior, Volume 15, Issue 1, January 2025.
ABSTRACT Objective Cognitive impairment is increasingly recognized as a complication of diabetes, yet the underlying pathology remains unclear. This study aims to investigate the roles of inflammation, oxidative stress, endothelial dysfunction, and neuronal damage in the neuropathology underlying diabetes related cognitive impairment.
Betul Sumbul‐Sekerci, Ozge Pasin, Ezgi Balkan, Abdusselam Sekerci   +3 more
wiley   +1 more source

Aristolochic acid‐related renal cell carcinoma exhibits a distinct tumor‐immune microenvironment favoring response to immune checkpoint blockade

The Journal of Pathology, Volume 264, Issue 4, Page 371-382, December 2024.
Abstract Immune checkpoint blockade (ICB) is currently the standard of care for metastatic renal cell carcinoma (RCC), but treatment responses remain unpredictable. Aristolochic acid (AA), a prevalent supplement additive in Taiwan, has been associated with RCC and induces signature mutations, although its effect on the tumor‐immune microenvironment ...
Po‐Hung Lin, Jason Yongsheng Chan, Peiyong Guan, Jing Han Hong, Abner Herbert Lim, Cedric Chuan‐Young Ng, Joe Poh Sheng Yeong, Jing Yi Lee, Wei Liu, Jeffrey Chun Tatt Lim, See‐Tong Pang, Bin Tean Teh   +11 more
wiley   +1 more source

Comparative 1H NMR Metabolomic Urinalysis of People Diagnosed with Balkan Endemic Nephropathy, and Healthy Subjects, in Romania and Bulgaria: A Pilot Study

Toxins, 2011
1H NMR spectroscopy of urine has been applied to exploring metabolomic differences between people diagnosed with Balkan endemic nephropathy (BEN), and treated by haemodialysis, and those without overt renal disease in Romania and Bulgaria.
Draga Toncheva, Diana Tatu, Calin Tatu, Andrew Nicholls, Mirela Modalca, Peter Mantle   +5 more
doaj   +1 more source

Prevalence and concentration of Ochratoxin A in beer: A global systematic review, meta‐analysis, and health risk assessment

Food Science &Nutrition, Volume 12, Issue 11, Page 8503-8514, November 2024.
In the current study, levels and prevalence of Ochratoxin A (OTA) in beer were meta‐analyzed and non‐carcinogenic risk was calculated by the target hazard quotient. Thirty papers with 70 data reports were included in our study. The pooled prevalence of OTA was 50.60%, 95% CI (confidence interval) (36.97–64.19). Five countries with the highest levels of
Yadolah Fakhri, Vahid Ranaei, Zahra Pilevar, Olga F. Belaia, Natalia V. Kolaeva, Mansour Sarafraz, Amin Mousavi Khaneghah   +6 more
wiley   +1 more source

Association of SOD2 (rs4880) and GPX1 (rs1050450) Gene Polymorphisms with Risk of Balkan Endemic Nephropathy and its Related Tumors

Medicina, 2019
Background and Objectives: Experimental data show that superoxide dismutase 2 (SOD2) is involved in ochratoxin (OTA)-induced nephrotoxicity, whereas clinical data indicate the role of SOD2 rs4880 or glutathione peroxidase 1 (GPX1) rs1050450 polymorphisms
Biljana Dragicevic, Sonja Suvakov, Djurdja Jerotic, Zorica Reljic, Ljubica Djukanovic, Ivanka Zelen, Marija Pljesa-Ercegovac, Ana Savic-Radojevic, Tatjana Simic, Dejan Dragicevic, Marija Matic   +10 more
doaj   +1 more source