Results 221 to 230 of about 128,512 (289)

Ir(III) Complexes Convert Cold to Hot Tumors via Ferroptosis/Necroptosis‐Driven Immunogenic Cell Death and Photosensitized CD47 Downregulation

Advanced Science, EarlyView.
Red‐light‐activated Ir1 overcomes hypoxia tolerance and adapts to the immunosuppressive tumor microenvironment, converting immunologically cold tumors into inflamed hot microenvironments. This conversion is driven by synergistic induction of immunogenic cell death through coordinated ferroptosis‐necroptosis pathways and spatiotemporally controlled ...
Long‐Bo Yu, Peng Wang, Qing‐Hua Shen, Qi‐Xin Guan, Zhi‐Yuan Li, Ying‐Ying Han, Xin‐Yi Zhang, Qing‐Yuan Hu, Cai‐Ping Tan   +8 more
wiley   +1 more source

Native mass spectrometry of membrane proteins reconstituted in peptidiscs. [PDF]

RSC Chem Biol
Deedwania A, Wang Y, Robinson CV, Bolla JR.   +3 more
europepmc   +1 more source

Reviewer #2 (Public Review): Bam complex associated proteins in Escherichia coli are functionally linked to peptidoglycan biosynthesis, membrane fluidity and DNA replication

Jack A Bryant, Kara A Staunton, Hannah M Doherty, Micheal B Alao, Xuyu Ma, Joanna Morcinek-Orłowska, Emily CA Goodall, Jessica Gray, Mathew Milner, Jeffrey A Cole, Felicity de Cogan, Timothy J Knowles, Monika Glinkowska, Danesh Moradigaravand, Ian R Henderson, Manuel Banzhaf   +15 more
openalex   +1 more source

Bam complex associated proteins in Escherichia coli are functionally linked to peptidoglycan biosynthesis, membrane fluidity and DNA replication [PDF]

Jack A. Bryant, Kara A Staunton, Hannah M. Doherty, Micheal B. Alao, Xuyu Ma, Joanna Morcinek-Orłowska, Emily C. A. Goodall, Jessica Gray, Mathew Milner, Jeffrey A. Cole, Felicity de Cogan, Timothy J. Knowles, Monika Glinkowska, Danesh Moradigaravand, Ian R. Henderson, Manuel Banzhaf   +15 more
openalex   +1 more source

The Evolutionarily Conserved TPM1 Super‐Enhancer Drives Skeletal Muscle Regeneration via Mechanotransduction Signaling

Advanced Science, EarlyView.
By integrating biomechanical and epigenetic cues, the evolutionarily conserved TPM1 super‐enhancer drives myogenesis via TEAD4‐mediated chromatin looping. This mechanism produces species‐specific outputs (linear TPM1 mRNA in mice and CircTPM1 in bovine) that activate PI3K/AKT mechanotransduction and the MYH10/MYL3 axis to execute cytoskeletal ...
Ruimen Zhang, Wanyou Feng, Yanyan Yang, Yu Pan, Chaoxia Zou, Leyi Wang, Sanbao Zhang, Yimin Zhao, Yongmei Wu, Jinling Wang, Jianwei Zou, Kehe Cen, Yongwang Zhang, Han Huang, Yurong Xu, Li Zhong, Hailong Gong, Juanru Cheng, Jingyuan Liang, Zihua Zheng, Qinyang Jiang, Jingwei Wei, Hui Li, Minhui Liang, Deshun Shi, Sufang Yang, Yanfei Deng, Yingming Wei   +27 more
wiley   +1 more source

Tracking functional recovery in a community-based substance use disorder program: a five-year descriptive evaluation using the brief addiction monitor. [PDF]

Addict Sci Clin Pract
Phillips C, Mejia MC, Peters D, Kalathoor J, Sacca L, Andric B.   +5 more
europepmc   +1 more source

Aberrant Splicing Signatures Underpin Oligodendrocyte Damage in ALS and Neuron Loss in FTD

Advanced Science, EarlyView.
Integrating bulk and single‐nucleus RNA‐seq from ALS and FTD patients, we revealed distinct cellular dysfunctions, with severe oligodendrocyte damage in ALS and pronounced neuron loss in FTD. We identified cell‐type‐specific aberrant splicing events as potential biomarkers with robust classification performance, some of which produce de novo peptides ...
Chen Du, Yinming Li, Rong Wu, Yufei Shen, Jiayi Yang, Xuan Xiao, Yu Zhou   +6 more
wiley   +1 more source

Ssrp governs germline development independent of the FACT complex in Drosophila spermatogenesis. [PDF]

Cell Biosci
Tan X, Lou Y, Yin Z, Zhao J, Wang J, Jin J, Wang Y, Xi Y, Yang X, Zheng H.   +9 more
europepmc   +1 more source

Local Lyapunov Analysis via Micro-Ensembles: finite-time Lyapunov exponent Estimation and KNN-Based Predictive Comparison in Complex-Valued BAM Neural Networks [PDF]

Yazhini Muruganantham, Andrei Velichko, Surjeet Rajendran   +2 more
openalex   +1 more source

PRDM1+ Malignant Cells Mediate an Immunosuppressive Landscape and Resistance to Neoadjuvant Chemoradiotherapy and Immunotherapy in Esophageal Squamous Cell Carcinoma

Advanced Science, EarlyView.
Integrated scRNA‐seq, scTCR‐seq analysis, and functional assays identify PRDM1+ malignant epithelial cells with hyper lipid peroxidation characteristics that demonstrate reduced responsiveness to the nICRT treatment. Principal factor PRDM1 activates cysteine metabolism genes to modulate lipid peroxidation (an intrinsic cellular pathway related to ...
Dijian Shen, Rui Li, Yong She, Xuefei Liu, Yuanyang Huang, Yongling Ji, Keying Chen, Zhengbo Song, Runzhe Chen, Xuan Li, Qi Zhao, Qixun Chen, Ming Chen   +12 more
wiley   +1 more source