Results 61 to 70 of about 193,750 (307)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Elimination of Noise Distortion for OFDM Systems by Compressed Sensing Based on Distance Metric

open access: yesIEEE Access, 2020
The clipping method is often applied to reduce the peak to average ratio (PAPR) of orthogonal frequency division multiplexing (OFDM). However, this method will cause in-band distortion, which increases the bit error rate (BER) at the receiver.
Ning Li, Mengjia Huang, Zhongliang Deng
doaj   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

open access: yesFEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini   +2 more
wiley   +1 more source

2190 Longitudinal changes in EEG power envelope connectivity are proportional to motor recovery in chronic stroke patients

open access: yesJournal of Clinical and Translational Science, 2018
OBJECTIVES/SPECIFIC AIMS: The objective of this study is to determine the degree to which the use of a contralesionally-controlled brain-computer interface for stroke rehabilitation drives change in interhemispheric motor cortical activity. METHODS/STUDY
Joseph B. Humphries   +3 more
doaj   +1 more source

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

open access: yesFEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez   +5 more
wiley   +1 more source

Effect of compression modalities for recovery on wrestlers' biomarkers in one day tournament

open access: yesCentral European Journal of Sport Sciences and Medicine, 2019
The aim of the study was to investigate the effect of different compression modalities as to recovery enhancement on some biomarkers in wrestlers. Serum creatinine, lactic acid and glucose level were tested in elite wrestlers before a match-up, 3 ...
Mohamed S. Ghoraba, Marwa F. Ghazy
doaj   +1 more source

The recovery of distorted band-limited signals

open access: yesJournal of Mathematical Analysis and Applications, 1961
In der Arbeit wird ein bekanntes Problem der Nachrichtentechnik allgemein formuliert und streng mathematisch behandelt. Es wird gezeigt, wie man bandbegrenzte Signale identifizieren kann, die durch eine Frequenz-Kompandierung verformt worden sind. Gegeben ist eine quadratisch integrierbare Funktion der Zeit \(f(t)\) (Plancherelsche Theorie), deren ...
Landau, H.J, Miranker, W.L
openaire   +2 more sources

Evolutionary dynamics of the chloroplast genome in Daphne (Thymelaeaceae): comparative analysis with related genera and insights into phylogenetics

open access: yesFEBS Open Bio, EarlyView.
Comparative analysis of chloroplast genomes from 14 genera of Thymelaeaceae revealed variation in gene content, ranging from 128 to 142 genes, primarily influenced by IR expansion/contraction events and pseudogenization of ndhF, ndhI, and ndhG. Two large inversions were detected within the large single‐copy region, including a synapomorphic inversion ...
Abdullah   +8 more
wiley   +1 more source

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

open access: yesFEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito   +3 more
wiley   +1 more source

Prognostic Factors Associated With Early Recovery From Veno‐Arterial Extracorporeal Membrane Oxygenation Support in Patients With Fulminant Myocarditis

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Fulminant myocarditis is life‐threatening and often requires mechanical circulatory support. Predicting its clinical course is crucial, yet data on early recovery predictors, particularly with veno‐arterial extracorporeal membrane oxygenation,
Tomomi Ueda   +18 more
doaj   +1 more source

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