Results 61 to 70 of about 206,143 (262)

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

Trans-Atlantic Banded Pigeon Recovery

The Canadian field-naturalist, 1928
(Uploaded by Plazi from the Biodiversity Heritage Library) No abstract provided.
openaire   +2 more sources

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Multi-Channel Super-Resolution Reconstruction Model Based on Dual-Band Weather Radar Fusion

Remote Sensing
Dual-band weather radar networks enable complementary multi-radar observations, improving the accuracy, three-dimensional characterization, and early warning capability for severe convective weather.
Siran Yang, Yao Li, Fei Ye, Qiangyu Zeng, Jianxin He, Hao Wang, Tiantian Yu   +6 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Optimal complexity recovery of band- and energy-limited signals II

Journal of Complexity, 1989
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Marek A. Kowalski, Frank Stenger
openaire   +1 more source

Prognostic Factors Associated With Early Recovery From Veno‐Arterial Extracorporeal Membrane Oxygenation Support in Patients With Fulminant Myocarditis

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Fulminant myocarditis is life‐threatening and often requires mechanical circulatory support. Predicting its clinical course is crucial, yet data on early recovery predictors, particularly with veno‐arterial extracorporeal membrane oxygenation,
Tomomi Ueda, Eisuke Amiya, Masaru Hatano, Kosuke Inoue, Junichi Ishida, Shun Minatsuki, Hiroki Yagi, Chie Bujo, Yoshitaka Isotani, Nobutaka Kakuda, Takanobu Yamada, Norifumi Takeda, Hiroshi Akazawa, Koshiro Kanaoka, Kenji Onoue, Yoshihiko Saito, Shungo Hikoso, Issei Komuro, Norihiko Takeda   +18 more
doaj   +1 more source

2190 Longitudinal changes in EEG power envelope connectivity are proportional to motor recovery in chronic stroke patients

Journal of Clinical and Translational Science, 2018
OBJECTIVES/SPECIFIC AIMS: The objective of this study is to determine the degree to which the use of a contralesionally-controlled brain-computer interface for stroke rehabilitation drives change in interhemispheric motor cortical activity. METHODS/STUDY
Joseph B. Humphries, David T. Bundy, Eric C. Leuthardt, Thy N. Huskey   +3 more
doaj   +1 more source