Results 91 to 100 of about 1,395,579 (341)

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

KDANet: a farmland extraction network using band selection and dual attention fusion – a case study of paddy fields and irrigated land in Qingtongxia, China

Geocarto International
Food security is a critical global issue, and accurate monitoring of farmland is essential to address this challenge. However, farmland extraction accuracy is often hindered by variations in land types and scales.
Jianping Pan, Chen Qi, Huijuan Zhang, Yong Hu, Zhaohui Ren, Zong He, Xunxun Wang, Yimeng Li, Yan Wang, Juan Xie   +9 more
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

A Physics-Guided Machine Learning Algorithm for Non-Ionizing Femur Fracture Classification from RF Spectral Data

Algorithms
This paper presents a physics-guided machine learning algorithm for classifying femur fracture presence and subtype using non-ionising radiofrequency (RF) spectral data.
Prince O. Siaw, Yacine Chahba, Ebenezer Adjei, Ahmad Aldelemy, Salamatu Ibrahim, Raed Abd-Alhameed   +5 more
doaj   +1 more source

Lossless Compression for Hyperspectral Images based on Adaptive Band Selection and Adaptive Predictor Selection [PDF]

, 2020
Fuquan Zhu, Huajun Wang, Liping Yang, Changguo Li, Sen Wang   +4 more
openalex   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

New Measurements of Fine-Scale CMB Polarization Power Spectra from CAPMAP at Both 40 and 90 GHz

, 2008
We present new measurements of the cosmic microwave background (CMB) polarization from the final season of the Cosmic Anisotropy Polarization MAPper (CAPMAP). The data set was obtained in winter 2004-2005 with the 7 m antenna in Crawford Hill, New Jersey,
B. Winstein, C. Bischoff, Chu T. S., D. Barkats, D. Samtleben, G. W. Nixon, Haslam C. G. T., J. J. McMahon, J. O. Gundersen, K. M. Smith, K. Vanderlinde, L. Hyatt, M. M. Hedman, P. Farese, S. T. Staggs, T. Gaier   +15 more
core   +1 more source

An HST/WFPC2 Snapshot Survey of 2MASS-Selected Red QSOs [PDF]

, 2003
Using simple infrared color selection, 2MASS has found a large number of red, previously unidentified, radio-quiet QSOs. Although missed by UV/optical surveys, the 2MASS QSOs have K-band luminosities that are comparable to "classical" QSOs. This suggests
Andrew R. Marble, Antonucci R., Boyle B. J., Brant O. Nelson, Comastri A., Dean C. Hines, Dunlop J. S., Gary D. Schmidt, Holmberg E. B., Jason A. Surace, Lee Armus, Paul S. Smith, Roc M. Cutri   +12 more
core   +2 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Deep Spectral Feature Learning With Evolutionary Band Selection for Environmental Monitoring of Plastic Debris

IEEE Access
The proliferation of plastic debris in terrestrial and aquatic environments poses significant ecological and monitoring challenges worldwide. Hyperspectral imaging (HSI) provides fine-grained spectral signatures that enable the reliable identification of
R. Anand
doaj   +1 more source