Results 91 to 100 of about 319,748 (260)

CSNR and JMIM Based Spectral Band Selection for Reducing Metamerism in Urban Driving

IEEE Open Journal of Intelligent Transportation Systems
Protecting Vulnerable Road Users (VRU) remains a key challenge in automotive perception, particularly when RGB imagery exhibits metameric ambiguity under challenging illumination. Hyperspectral Imaging (HSI) can provide material-dependent cues beyond RGB,
Jiarong Li, Imad Ali Shah, Diarmaid Geever, Fiachra Collins, Enda Ward, Martin Glavin, Edward Jones, Brian Deegan   +7 more
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Deep Spectral Feature Learning With Evolutionary Band Selection for Environmental Monitoring of Plastic Debris

IEEE Access
The proliferation of plastic debris in terrestrial and aquatic environments poses significant ecological and monitoring challenges worldwide. Hyperspectral imaging (HSI) provides fine-grained spectral signatures that enable the reliable identification of
R. Anand
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Hyperspectral Band Selection for Ground Fuel Classification for Prescribed Fires

Remote Sensing
Hyperspectral image (HSI) analysis plays a central role in remote sensing tasks requiring fine-grained material discrimination, vegetation health assessment, and post-disturbance monitoring.
Mahmad Isaq Karankot, Ethan M. Glenn, Muhammad Umer Masood, Xiaobing Zhou, Bradley M. Whitaker   +4 more
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Satellite-Based Machine Learning for Temporal Assessment of Water Quality Parameter Prediction in a Coastal Shallow Lake

Journal of Marine Science and Engineering
Satellite remote sensing increasingly supports water quality monitoring, yet the temporal transferability of machine learning (ML) models remains insufficiently tested, particularly in coastal shallow lakes subject to hydrological variability. This study
Anja Batina, Ljiljana Šerić, Andrija Krtalić, Ante Šiljeg   +3 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Trait-Dependent Effects of Band Selection on Predicting Soybean Biomass, Leaf Area Index, and Canopy Cover from Hyperspectral Reflectance

Remote Sensing
Predicting canopy traits non-destructively is important for understanding crop growth and improving phenotyping efficiency. Hyperspectral reflectance provides detailed spectral information, but the role of band selection in regression-based trait ...
Etsushi Kumagai, Takayuki Yabiku, Yusuke Masuya, Kensuke Kimura, Erina Fushimi, Ryosuke Nomiyama   +5 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source