Results 81 to 90 of about 314,709 (295)

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

HYBASE - HYperspectral BAnd SElection tool [PDF]

open access: yes, 2008
Band selection is essential in the design of multispectral sensor systems. This paper describes the TNO hyperspectral band selection tool HYBASE. It calculates the optimum band positions given the number of bands and the width of the spectral bands ...
Bekman, H.H.P.T.   +2 more
core  

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

Rapid Non-Destructive Detection of Rice Seed Vigor via Terahertz Spectroscopy

open access: yesAgriculture
Rice seed vigor significantly impacts yield, making the selection of high-vigor seeds crucial for agricultural production. Traditional methods for assessing seed vigor are time-consuming and destructive.
Jun Hu   +5 more
doaj   +1 more source

Reducing the Effect of the Endmembers’ Spectral Variability by Selecting the Optimal Spectral Bands

open access: yesRemote Sensing, 2017
Variable environmental conditions cause different spectral responses of scene endmembers. Ignoring these variations affects the accuracy of fractional abundances obtained from linear spectral unmixing. On the other hand, the correlation between the bands
Omid Ghaffari   +2 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Weed Detection: Innovative Hyperspectral Image Analysis for Classification and Band Selection of Site-Specific and Selective Weeding Robot

open access: yesAgronomy
Weeding in melon and watermelon fields requires selective and pinpoint operation because the crop plants are sensitive to herbicides and tend to grow on the ground in all directions.
Asi Lazar   +3 more
doaj   +1 more source

Evaluation of Informative Bands Used in Different PLS Regressions for Estimating Leaf Biochemical Contents from Hyperspectral Reflectance

open access: yesRemote Sensing, 2019
Partial least squares (PLS) regression models are widely applied in spectroscopy to estimate biochemical components through hyperspectral reflected information.
Jia Jin, Quan Wang
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

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