Results 61 to 70 of about 1,395,579 (341)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

An Improved Ant Colony Algorithm for Optimized Band Selection of Hyperspectral Remotely Sensed Imagery

open access: yesIEEE Access, 2020
The ant colony algorithm (ACA) has been widely used for reducing the dimensionality of hyperspectral remote sensing imagery. However, the ACA suffers from problems of slow convergence and of local optima (caused by loss of population diversity).
Xiaohui Ding   +6 more
doaj   +1 more source

Validity of the rigid band picture for the t-J model

open access: yes, 1994
We present an exact diagonalization study of the doping dependence of the single particle Green's function in 16, 18 and 20 site clusters of t-J model. We find evidence for rigid-band behaviour starting from the half-filled case: upon doping, the topmost
A. P. Kampf   +18 more
core   +2 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Spectroscopic Detection of Carbon Monoxide in Two Late-type T Dwarfs [PDF]

open access: yes, 2008
M band spectra of two late-type T dwarfs, 2MASS J09373487+2931409, and Gliese 570D, confirm evidence from photometry that photospheric CO is present at abundance levels far in excess of those predicted from chemical equilibrium. These new and unambiguous
Bishop   +42 more
core   +2 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Editorial for Special Issue “Hyperspectral Imaging and Applications”

open access: yesRemote Sensing, 2019
Due to advent of sensor technology, hyperspectral imaging has become an emerging technology in remote sensing. Many problems, which cannot be resolved by multispectral imaging, can now be solved by hyperspectral imaging.
Chein-I Chang   +3 more
doaj   +1 more source

Anisotropic photoconductivity in graphene [PDF]

open access: yes, 2011
We investigate the photoconductivity of graphene within the relaxation time approximation. In presence of the inter-band transitions induced by the linearly polarized light the photoconductivity turns out to be highly anisotropic due to the pseudospin ...
Echtermeyer T. J.   +7 more
core   +3 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Band Selection-Based Dimensionality Reduction for Change Detection in Multi-Temporal Hyperspectral Images

open access: yesRemote Sensing, 2017
This paper proposes to use band selection-based dimensionality reduction (BS-DR) technique in addressing a challenging multi-temporal hyperspectral images change detection (HSI-CD) problem. The aim of this work is to analyze and evaluate in detail the CD
Sicong Liu   +5 more
doaj   +1 more source

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