How phagocytic cells kill bacteria: Lessons from a professional killer
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley +1 more source
Secrecy Outage Performance of SWIPT Cognitive Radio Network With Imperfect CSI
We consider a cognitive radio (CR) network with simultaneous wireless information and power transfer (SWIPT) system having one base station (BS) with multiple antennas that acts as a secondary transmitter, one desired information receiver (IR) acting as ...
Ajay Singh +2 more
doaj +1 more source
Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source
A New Band Selection Methodology for Hyperspectral Sensors with Application to Target Detection [PDF]
This manuscript presents a novel methodology for band selection (BS) for hyperspectral sensors (HSs) tailored to target detection applications. The new selection strategy chooses a subset of bands that maximizes an objective function suitable for target ...
GRECO M +3 more
core +1 more source
Protocol for quantifying miRNA trafficking across the endosomal membrane
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source
Cracking the Code: Genotype–Phenotype Correlation Models in Sarcoglycanopathies
ABSTRACT Objective Sarcoglycanopathies are among the most severe limb‐girdle muscular dystrophies (LGMD), though milder presentations have been described. These diseases are primarily caused by missense variants, but the limited predictability of their effect on protein maturation, complex formation, and transport has hindered reliable genotype ...
Leonela Luce +72 more
wiley +1 more source
A New Band Selection Strategy for Target Detection in Hyperspectral Images [PDF]
This manuscript presents a novel methodology for band selection (BS) for hyperspectral sensors (HSs) tailored to target detection applications. The new selection strategy chooses a subset of bands that maximizes an objective function suitable for target ...
CORSINI, GIOVANNI +3 more
core +1 more source
ABSTRACT Background Ischemic stroke, a major cause of mortality and long‐term disability, results from the abrupt cessation of cerebral blood flow due to vascular occlusion or rupture. Icosapent Ethyl (EPA‐EE), approved for hypertriglyceridemia, has anti‐inflammatory and antithrombotic properties that may lessen ischemic damage.
Mitra Mahmoudi Meymand +5 more
wiley +1 more source
Bi‐ and Mono‐Allelic RFC1 Expansion in a North American Cohort With Idiopathic Axonal Neuropathy
ABSTRACT Objective RFC1 biallelic repeat expansion is increasingly recognized as a cause of chronic idiopathic axonal polyneuropathy (CIAP), but it remains challenging to know who to test. This study aims to determine the prevalence of biallelic and monoallelic RFC1 expansions and their corresponding neuropathy phenotypes in CIAP patients and identify ...
Amro M. Stino +25 more
wiley +1 more source
Exploiting Site-Specific Propagation Characteristics in Directional Search at 28 GHz
Simulation data from a ray-tracing tool applied in specific urban environments in the 28-GHz band suggest that the utilization of arbitrary base station (BS) angles in a directional search procedure may not be of maximum benefit for users located in non ...
Juan C. Aviles, Ammar Kouki
doaj +1 more source

