Results 91 to 100 of about 986 (161)

Broad‐Spectrum Antiviral Agents against SARS‐CoV‐2 Variants Inhibit the Conserved Viral Protein Nsp1–RNA Interaction

open access: yesAngewandte Chemie, Volume 136, Issue 47, November 18, 2024.
The demand for robust antiviral approaches is underscored by the continued COVID‐19 spread. SARS‐CoV‐2 Nsp1, highly conserved among SARS‐CoV‐2 variants, plays a pivotal role in controlling host protein expression and viral RNA translation. A small‐molecule Nsp1 inhibitor exhibited antiviral activity against various sarbecoviruses, signifying a ...
Wan Gi Byun   +7 more
wiley   +1 more source

A survey of RNA viruses in mosquitoes from Mozambique reveals novel genetic lineages of flaviviruses and phenuiviruses, as well as frequent flavivirus-like viral DNA forms in Mansonia [PDF]

open access: yes, 2020
Background: Mosquito-borne diseases involving arboviruses represent expanding threats to sub-Saharan Africa imposing as considerable burden to human and veterinary public health.
Abílio, Ana Paula   +9 more
core   +2 more sources

Infection of Severe Fever with Thrombocytopenia Syndrome Virus as a Cause of a Child’s Fever of Unknown Origin: A Case Report

open access: yesInfection and Drug Resistance, 2022
Yin Zhang, Ying Huang, Yuanhong Xu Department of Clinical Laboratory, The First Affiliated Hospital of Anhui Medical University, Hefei, People’s Republic of ChinaCorrespondence: Yuanhong Xu; Ying Huang, Department of Clinical Laboratory, The First ...
Zhang Y, Huang Y, Xu Y
doaj  

Development of an RT-LAMP−CRISPR/Cas12a assay for rapid and specific detection of Bandavirus dabieense

open access: yesJournal of Microbiology
Bandavirus dabieense, a single-stranded RNA virus, is the causative agent of severe fever with thrombocytopenia syndrome (SFTS), a disease associated with high fatality rates. Early and accurate diagnosis is essential for improving clinical outcomes, particularly given the limited therapeutic options and high mortality rates associated with SFTS ...
Bo Seung, Song   +10 more
openaire   +2 more sources

Comprehensive Surveillance of Severe Fever with Thrombocytopenia Syndrome Virus in Patients with Acute Febrile Illness, Wild Rodents, and Trombiculid Larval Mites, Thailand

open access: yesEmerging Infectious Diseases
Infection with severe fever with thrombocytopenia syndrome (Bandavirus dabieense) virus poses a substantial public health threat because of its high mortality rates and severe complications.
Piyada Linsuwanon   +11 more
doaj   +1 more source

Efficacy of favipiravir treatment for patients with severe fever with thrombocytopenia syndrome assessed with a historical control [PDF]

open access: yes
Severe fever with thrombocytopenia syndrome (SFTS) is a disease caused by SFTS virus (SFTSV), an RNA virus, and endemic to Asia. The case fatality rate in Japan is estimated to be approximately 27%.
20506084   +23 more
core  

Ultra-rapid detection of nuclear protein of severe fever with thrombocytopenia syndrome virus by colloidal gold immunochromatography assay [PDF]

open access: yesPeerJ
In 2009, severe fever with thrombocytopenia syndrome virus (SFTSV), also known as the Dabie bandavirus (DBV), was first discovered in Henan, China. It is a tick-borne zoonotic virus with a fatality rate ranging from 6% to 30%. Currently, we lack safe and
Zhiwei Huang   +13 more
doaj   +2 more sources

Urine of Cats with Severe Fever with Thrombocytopenia Syndrome: A Potential Source of Infection Transmission [PDF]

open access: yes
Severe fever with thrombocytopenia syndrome (SFTS), caused by infection with the SFTS virus, is an emerging fatal tick-borne zoonosis endemic to East Asia. Although SFTS is a tick-borne disease, the virus can be transmitted from animals with SFTS without
10359995   +25 more
core  

Receptor-binding proteins from animal viruses are broadly compatible with human cell entry factors [PDF]

open access: yes
Cross-species transmission of animal viruses poses a threat to human health. However, systematic experimental assessments of these risks remain scarce.
Andreu Moreno, Iván   +4 more
core   +2 more sources

Nine-year seroepidemiological study of severe fever with thrombocytopenia syndrome virus infection in feral horses in Cape Toi, Japan [PDF]

open access: yes
Severe fever with thrombocytopenia syndrome (SFTS) is a fatal zoonosis caused by ticks in East Asia. As SFTS virus (SFTSV) is maintained between wildlife and ticks, seroepidemiological studies in wildlife are important to understand the behavior of SFTSV
10359995   +35 more
core  

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