Results 121 to 130 of about 1,016 (136)

Reverse Genetics System for Heartland Bandavirus: NSs Protein Contributes to Heartland Bandavirus Virulence

Journal of Virology, 2022
Heartland bandavirus (HRTV) is a tick-borne virus identified in the United States in 2009. HRTV causes fever, fatigue, decreased appetite, headache, nausea, diarrhea, and muscle or joint pain in humans.
Masayuki Saijo, Chang Kweng Lim, Shigeru Morikawa   +2 more
exaly   +3 more sources

Pseudotyped Virus for Bandavirus

Advances in Experimental Medicine and Biology, 2023
The genus Bandavirus, belonging to family Phenuiviridae, order Bunyavirales, consists of eight tick-borne bunyaviruses. The Dabie bandavirus, formerly known as severe fever with thrombocytopenia virus (SFTSV), belongs to the genus Bandavirus. This emerging pathogen was first identified in central China in 2009.
Youchun Wang
exaly   +3 more sources

Developing and characterizing monoclonal antibodies of Guertu bandavirus nucleoprotein for developing methods of Guertu bandavirus and severe fever with thrombocytopenia syndrome virus detection

Brazilian Journal of Microbiology, 2023
Belonging to genus Bandavirus in Phenuiviridae family, Guertu bandavirus (GTV) is a potential pathogen closely related to severe fever with thrombocytopenia syndrome virus (SFTSV) and heartland virus (HRTV) associated with human diseases. Although the medical significance of GTV is not clear, there was serological evidence suggesting past infection ...
Hualin Wang, Shu Shen, Fei Deng
exaly   +3 more sources

Both of coagulopathy and neutrophil extracellular trap markers are associated with poor prognosis of dabie bandavirus infection.

Clinica Chimica Acta
BACKGROUND Severe fever with thrombocytopenia syndrome (SFTS), caused by Dabie bandavirus (DBV), has a high mortality. Coagulopathy and neutrophil extracellular traps (NETs) formation are implicated in disease progression, and their combined prognostic ...
Fan Bai, Zekai Lei, H. Bai, Dengju Li, N. Tang   +4 more
semanticscholar   +2 more sources

AN EXCEPTIONALLY RARE CASE OF FATAL ENCEPHALOPATHY: THE OVERLOOKED THREAT OF HEARTLAND BANDAVIRUS

CHEST
Brandon S Bharat, B. Acott, Amit Jatana, A. Ahasic   +3 more
semanticscholar   +2 more sources

A century-old museum sample reveals a bandavirus with modern day presence in northern European bats

bioRxiv
Abstract Ancient genome sequences provide invaluable insights into the origin and evolution of viral pathogens, offering a broader temporal perspective that extends well beyond the limited timespan of clinical data, which typically covers at most a few decades.
Udo Gieraths, J. Beheim-Schwarzbach, M. J. Pickin, Annika Beyer, L. Begeman, B. Hoffmann, Kore Schlottau, Martin Beer, Rainer G. Ulrich, Thomas Müller, C. Freuling, Tiina Mauno, M. V. D. van de Bildt, Vera C. Mols, V. Corman, F. Weber, Terry C. Jones, Christian Drosten   +17 more
semanticscholar   +2 more sources

Characterization of high-affinity antibodies against the surface Gc protein of Dabie bandavirus / severe fever with thrombocytopenia syndrome virus

Biochemistry and Biophysics Reports
Severe fever with thrombocytopenia syndrome virus (SFTSV) or Dabie bandavirus is an emerging pathogen responsible for SFTS. It is considered a novel threat to human health, given the high associated fatality.
Pyeonghwa Jeon, Bin Yoo, Yoonji Kim, Soyoung Lee, Hye-Min Woo, Hee‐Young Lim, Joo-Yeon Lee, Sora Park, Hansaem Lee   +8 more
semanticscholar   +1 more source

Tectorigenin Reduces Dabie bandavirus‐Induced Cytokine Storm by Regulating Toll‐Like Receptor 7/Extracellular Signal–Regulated Kinase Pathway

Chemical Biology and Drug Design
Severe fever with thrombocytopenia syndrome (SFTS) is a severe emerging infectious disease caused by Dabie bandavirus (DBV). Tectorigenin has been demonstrated to exert anti‐inflammatory effect.
Qian Zhang, Qinqin Pu, Zhengyi Jiang, Jie Zhao, Yan Dai, Nannan Hu, Yaping Han, Nan Jiang, Luchen Shi, Jiaying Zhao, Ouyang Ke, Huaying Huang, Ke Jin, Jun Li   +13 more
semanticscholar   +1 more source

Mutations that positively affect Bandavirus glycoprotein function on VSV vectored vaccines

Abstract Severe fever with thrombocytopenia syndrome virus (SFTSV) and Heartland virus (HRTV) are emerging tick-borne bandaviruses. They have high case fatality rates (10%), and no FDA-approved vaccines exist for disease prevention. SFTSV and HRTV are therefore identified as priority pathogens.
Raegan J. Petch, Philip Hicks, Jonna B. Westover, Brian B. Gowen, Paul Bates   +4 more
openaire   +1 more source

Discovery of a novel bandavirus using metagenomic sequencing in a retrospective analysis of an unresolved 2020 mortality event involving wild black vultures in the northeastern United States

Journal of Veterinary Diagnostic Investigation
Investigations of wildlife diseases and mortality events can sometimes lead to inconclusive results because of limitations in testing combined with an ever-increasing number of emerging viruses.
Lusajo Mwakibete, Axel O G Hoarau, V. Ahyong, Eric Waltari, Susan J. Bender, Sherrill Davison, Kevin D. Niedringhaus, Michelle Gibison, Roderick B. Gagne, Erica A. Miller, L. Murphy, Amy L. Kistler, C. Tato   +12 more
semanticscholar   +1 more source