Results 141 to 150 of about 884 (154)

Pseudotyped Virus for Bandavirus

2023
The genus Bandavirus, belonging to family Phenuiviridae, order Bunyavirales, consists of eight tick-borne bunyaviruses. The Dabie bandavirus, formerly known as severe fever with thrombocytopenia virus (SFTSV), belongs to the genus Bandavirus. This emerging pathogen was first identified in central China in 2009.
Ruifeng, Chen, Weijing, Huang, Youchun, Wang   +2 more
openaire   +2 more sources

Nonstructural Protein NSs Activates Inflammasome and Pyroptosis through Interaction with NLRP3 in Human Microglial Cells Infected with Severe Fever with Thrombocytopenia Syndrome Bandavirus

Journal of Virology, 2022
Encephalitis or encephalopathy during severe fever with thrombocytopenia syndrome (SFTS) is considered a critical risk factor leading to high mortality, but there have been no studies to date on the pathogenesis of encephalitis or encephalopathy caused by SFTS virus.
Chengfeng Gao, Yufeng Yu, Chunxia Wen, Zhifeng Li, Haida Ding, Xian Qi, Carol J. Cardona, Zheng Xing   +7 more
openaire   +2 more sources

Bergamottin, A Natural Bioactive Compound, Inhibits Dabie Bandavirus Infection In Vitro and In Vivo

Journal of Medical Virology
ABSTRACTSevere fever with thrombocytopenia syndrome (SFTS) is a novel, highly fatal disease caused by Dabie bandavirus (DBV), also referred to as severe fever with thrombocytopenia syndrome virus (SFTSV). DBV is endemic to many Asian countries, and its incidence has recently increased.
Yi Wan, Wenting Mao, Yang Liu, Wei Deng, Yuxia Hou, Wei Wang   +5 more
openaire   +1 more source

Coagulopathy in Dabie bandavirus infection is related to endogenous heparinoids release and mast cells activation

Thrombosis Research
The prolonged activated partial thromboplastin time (APTT) and thrombin time in patients infected with Dabie bandavirus (DBV) have been recognized to be poor prognostic indicators and attributed to a heparin-like effect rather than a decrease in coagulation factor levels.To clarify the correlation between endogenous heparinoids and coagulopathy in ...
Bin, Wang, Huan, Bai, Peihong, Yuan, Dengju, Li, Ning, Tang   +4 more
openaire   +2 more sources

First detection of Bandavirus dabieense in ticks collected from migratory birds in the Republic of Korea

Acta Tropica
The causative agent of severe fever with thrombocytopenia syndrome (SFTS) is Bandavirus dabieense, an emerging tick-borne zoonotic pathogen. Migratory birds have often been suggested as potential carriers of ticks that can transmit Bandavirus dabieense; however, their role remains unclear.
Seong-Ryeong Ji, Hye-Ryung Byun, Mi-Sun Rieu, Sun-Woo Han, Hyun-Young Nam, Seulgi Seo, Se-Young Park, Hwa-Yeon Kang, Chang-Yong Choi, So-Yeon Cho, Bo-Yeon Hwang, Joon-Seok Chae   +11 more
openaire   +2 more sources

Tectorigenin Reduces Dabie bandavirus‐Induced Cytokine Storm by Regulating Toll‐Like Receptor 7/Extracellular Signal–Regulated Kinase Pathway

Chemical Biology & Drug Design
ABSTRACTSevere fever with thrombocytopenia syndrome (SFTS) is a severe emerging infectious disease caused by Dabie bandavirus (DBV). Tectorigenin has been demonstrated to exert anti‐inflammatory effect. Here, we aimed to investigate the effects of tectorigenin on DBV‐induced cytokine storm.
Qian Zhang, Qinqin Pu, Zhengyi Jiang, Jie Zhao, Yan Dai, Nannan Hu, Yaping Han, Nan Jiang, Luchen Shi, Jiaying Zhao, Ke Ouyang, Huaying Huang, Ke Jin, Jun Li   +13 more
openaire   +2 more sources

Host factor MxA restricts Dabie bandavirus infection by targeting the viral NP protein to inhibit NP-RdRp interaction and ribonucleoprotein activity

Journal of Virology
ABSTRACT Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease with high case mortality rates, which is caused by Dabie bandavirus (DBV), a novel pathogen also termed as SFTS virus (SFTSV). Currently, no specific therapeutic drugs or vaccines are available for SFTS.
Meng Chang, Yuan-Qin Min, Zhao Xu, Fei Deng, Hualin Wang, Yun-Jia Ning   +5 more
openaire   +2 more sources

A century-old museum sample reveals a bandavirus with modern day presence in northern European bats

AbstractAncient genome sequences provide invaluable insights into the origin and evolution of viral pathogens, offering a broader temporal perspective that extends well beyond the limited timespan of clinical data, which typically covers at most a few decades.
Udo Gieraths, Jörn Beheim-Schwarzbach, Matthew J. Pickin, Annika Beyer, Lineke Begeman, Bernd Hoffmann, Kore Schlottau, Martin Beer, Rainer G. Ulrich, Thomas Müller, Conrad M. Freuling, Tiina Mauno, Marco van de Bildt, Vera C. Mols, Victor M. Corman, Friedemann Weber, Terry C. Jones, Christian Drosten   +17 more
openaire   +1 more source

The implication of abnormal routine coagulation parameters in Dabie bandavirus infection

Scandinavian Journal of Clinical and Laboratory Investigation
Tianzhu Zhang, Huan Bai, Bin Wang, Dengju Li, Ning Tang   +4 more
openaire   +1 more source

Isolation and Quantification of Dabie bandavirus

Diana Fernández, Patricia V. Aguilar
openaire   +1 more source