Results 141 to 150 of about 986 (161)

Reverse Genetics System for Heartland Bandavirus: NSs Protein Contributes to Heartland Bandavirus Virulence

Journal of Virology, 2022
Heartland bandavirus (HRTV) is a tick-borne virus identified in the United States in 2009. HRTV causes fever, fatigue, decreased appetite, headache, nausea, diarrhea, and muscle or joint pain in humans.
Satoshi Taniguchi, Takuya Inagaki, Tadaki Suzuki   +2 more
exaly   +3 more sources

Pseudotyped Virus for Bandavirus

Advances in Experimental Medicine and Biology, 2023
The genus Bandavirus, belonging to family Phenuiviridae, order Bunyavirales, consists of eight tick-borne bunyaviruses. The Dabie bandavirus, formerly known as severe fever with thrombocytopenia virus (SFTSV), belongs to the genus Bandavirus. This emerging pathogen was first identified in central China in 2009.
Ruifeng Chen, Youchun Wang
exaly   +3 more sources

Developing and characterizing monoclonal antibodies of Guertu bandavirus nucleoprotein for developing methods of Guertu bandavirus and severe fever with thrombocytopenia syndrome virus detection

Brazilian Journal of Microbiology, 2023
Belonging to genus Bandavirus in Phenuiviridae family, Guertu bandavirus (GTV) is a potential pathogen closely related to severe fever with thrombocytopenia syndrome virus (SFTSV) and heartland virus (HRTV) associated with human diseases. Although the medical significance of GTV is not clear, there was serological evidence suggesting past infection ...
Liyan Fu, Hualin Wang, Fei Deng
exaly   +3 more sources

Isolation and Quantification of Dabie bandavirus

Methods in Molecular Biology
Virus isolation is an important and critical method used for the diagnosis of emerging and re-emerging viral pathogens. The process involves the use of in vitro cell culture (most common) or suckling mice and relies on proper handling and storage of the samples prior to testing.
Diana Fernández, Patricia V Aguilar
exaly   +3 more sources

The pathogen of SFTS: Bandavirus dabieense phylogenetic analysis and development of an online tool for genotyping

Acta Tropica
Bandavirus dabieense (DBV), the pathogen of SFTS that was included in the WHO's list of priority infectious diseases requiring urgent attention in 2017, belongs to a large and highly diverse class of RNA viruses. Currently, the lack of a unified DBV genotyping standard and the confusion among common genotyping systems cause research result ...
Hongxiao Wu, Yuanyuan Zhang, Zhihai Chen   +2 more
exaly   +3 more sources

The implication of abnormal routine coagulation parameters in Dabie bandavirus infection

Scandinavian Journal of Clinical and Laboratory Investigation
Prolonged activated partial thromboplastin time (APTT) and thrombin time (TT), normal prothrombin time (PT) and elevated D-dimer level are typical manifestation of routine coagulation parameters in patients infected with Dabie bandavirus (DBV), infection-induced coagulation activation and consumption, and a heparin-like effect due to endogenous heparan
Tianzhu, Zhang, Huan, Bai, Bin, Wang, Dengju, Li, Ning, Tang   +4 more
openaire   +2 more sources

Coagulopathy in Dabie bandavirus infection is related to endogenous heparinoids release and mast cells activation

Thrombosis Research
The prolonged activated partial thromboplastin time (APTT) and thrombin time in patients infected with Dabie bandavirus (DBV) have been recognized to be poor prognostic indicators and attributed to a heparin-like effect rather than a decrease in coagulation factor levels.To clarify the correlation between endogenous heparinoids and coagulopathy in ...
Ning Tang
exaly   +3 more sources

Bergamottin, A Natural Bioactive Compound, Inhibits Dabie Bandavirus Infection In Vitro and In Vivo

Journal of Medical Virology
ABSTRACTSevere fever with thrombocytopenia syndrome (SFTS) is a novel, highly fatal disease caused by Dabie bandavirus (DBV), also referred to as severe fever with thrombocytopenia syndrome virus (SFTSV). DBV is endemic to many Asian countries, and its incidence has recently increased.

exaly   +3 more sources

Development of a broad-spectrum multiepitope vaccine against dabie bandavirus through immunoinformatic approaches

International Immunopharmacology
Dabie bandavirus is an emerging tick-borne disease-causing high morbidity and mortality in East Asia, with no vaccines or targeted antiviral therapies. In this study, a multiepitope vaccine was designed using an immunoinformatic strategy to provide robust immune protection.
Hafiz Muzzammel Rehman, Ashwag Shami
exaly   +3 more sources

First detection of Bandavirus dabieense in ticks collected from migratory birds in the Republic of Korea

Acta Tropica
The causative agent of severe fever with thrombocytopenia syndrome (SFTS) is Bandavirus dabieense, an emerging tick-borne zoonotic pathogen. Migratory birds have often been suggested as potential carriers of ticks that can transmit Bandavirus dabieense; however, their role remains unclear.
Seong-Ryeong Ji, Hye-Ryung Byun, Mi-Sun Rieu, Sun-Woo Han, Hyun-Young Nam, Seulgi Seo, Se-Young Park, Hwa-Yeon Kang, Chang-Yong Choi, So-Yeon Cho, Bo-Yeon Hwang, Joon-Seok Chae   +11 more
openaire   +2 more sources