Results 11 to 20 of about 4,567,077 (308)
C‐mannosylation is a unique form of protein glycosylation. In this study, we demonstrated that ADAMTS1 is C‐mannosylated at Trp562 and Trp565 in human testicular germ cell tumor NEC8 cells. We found that C‐mannosylation of ADAMTS1 is essential for its secretion, processing, enzymatic activity, and ability to promote vasculogenic mimicry. These findings
Takato Kobayashi +5 more
wiley +1 more source
Phytohormone brassinosteroid‐induced gene regulation by the transcription factor BIL1/BZR1 involves redox‐dependent DNA‐binding alternation and interaction with the transcription factor PIF4. The reduced BIL1/BZR1 dimer binds preferred cis‐elements, while oxidation alters its oligomerization state and disrupts DNA‐binding ability.
Shohei Nosaki +4 more
wiley +1 more source
A historiography centred around the year 1900 produced a synchronic, not a diachronic, view. The kaleidoscopic character of the present monograph is therefore consistent with the basic options of the whole project.
J. Bank
doaj +1 more source
Gender Mainstreaming Case Study - India: Chhattisgarh Irrigation Development Project [PDF]
Project Goals and Results • The Chhattisgarh Irrigation Development Project (CIDP) aimed to increase agricultural productivity, improve rural livelihoods, and reduce poverty by improving irrigation delivery, enhancing agricultural practices, and ...
Asian Development Bank
core +1 more source
Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer +10 more
wiley +1 more source
Gender Equality Results Case Study - Bangladesh: Second Urban Primary Health Care Project [PDF]
Development Aims and Impacts. The Urban Primary Health Care Project strengthened and expanded primary health care infrastructure and services with a focus on the urban poor.
Asian Development Bank
core +1 more source
Primes in short intervals on curves over finite fields [PDF]
We prove an analogue of the Prime Number Theorem for short intervals on a smooth projective geometrically irreducible curve of arbitrary genus over a finite field.
Bank, E., Foster, T.
core +2 more sources
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley +1 more source
Beneath the gloss of Asia’s newfound prosperity lies an unsettling reality. Rising inequality has denied the benefits of Asia’s economic growth to many millions of its citizens.
Asian Development Bank
core +1 more source
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez +17 more
wiley +1 more source

