Results 51 to 60 of about 4,401,243 (304)
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Literatuur en Duitse bezetting, 1940-1945
BMGN: Low Countries Historical Review, 1995 A. Venema, Verleden tijd. Memoires; P. Calis, Het ondergronds verwachten. Schrijvers en tijdschriften tussen 1941 en 1945 P. Calis, Speeltuin van de titaantjes. Schrijvers en tijdschriften tussen 1945 en 1948 A.
J.Th.M. Bank
doaj +1 more source
Innovative Asia: Advancing the Knowledge-Based Economy - Highlights of the Forthcoming ADB Study Report [PDF]
, 2014 [Excerpt] The development of knowledge-based economies (KBEs) is both an imperative and an opportunity for developing Asia. It is an imperative to sustain high rates of growth in the future and an opportunity whereby emerging economies can draw from ...
Asian Development Bank
core +1 more source
Banking sector problems: Causes, Resolutions and Consequences [PDF]
, 2000 Until the mid 1980s, commercial banking was the main lever of soft budgetary constraint. Commercial banks were under the control of their founding enterprises and their basic function was to approve the cheapest possible credit to their founders.
Jankov, Ljubinko
core +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Building Power from Below: Chilean Workers take on Walmart [PDF]
, 2017 [Excerpt] A story that involves as its main players workers and Walmart does not usually have a happy ending for labor, so the counternarrative offered by Building Power from Below is must reading for activists and union personnel as well as scholars.
Muñoz, Carolina Bank
core +1 more source
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
FEBS Open Bio, EarlyView.Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold +11 more
wiley +1 more source
FEBS Open Bio, EarlyView.ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand +2 more
wiley +1 more source
BANK CHARACTERISTICS, FIRM CHARACTERISTICS, BANK FUNDING STRUCTURE AND BANK LENDING DURING LIQUIDITY CRISIS USING A DYNAMIC PANEL MODEL (Study on Manufacturing Firms Listed on IDX 2011 – 2014) [PDF]
, 2016 This study aimed to see the behaviour of bank lending to manufacturing companies. The behaviour of bank lending is examined from the supply side, demand side and the structure of bank funding especially under a liquidity crisis. This study emphasize that
ARFINTO, Erman Denny +1 more
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