Results 251 to 260 of about 1,081,363 (314)

PRELID1 and VDAC3 Coordinate a Senescence‐Like State in Germinal Center B Cells to Promote IL‐7–Driven Antitumor Immunity in Colorectal Cancer

Advanced Science, EarlyView.
Colorectal cancer is characterized by an immunosuppressive microenvironment that limits immunotherapy efficacy. We identify a senescence‐like state in germinal center B cells driven by the PRELID1–VDAC3 axis, which promotes IL‐7 secretion, alleviates CD8+ T‐cell exhaustion, and enhances antitumor immunity. Targeting this pathway improves responsiveness
Yuhan Liao, Huimeng Xu, Xinghua Zhuo, Shupeng Hu, Lanhui Huang, Zhe Hao, Jianxiong Chen, Yulu Wang, Jun Zhou   +8 more
wiley   +1 more source

Heidelberg Perioperative Deep Data Registry and Biomaterial Bank (HeiPoDD Registry and Bio Bank): study protocol for a prospective single-centre registry and biobank for patients undergoing high-risk non-cardiac surgery in a German university hospital. [PDF]

BMJ Open
Hölzer HT, Niklas C, Tenckhoff S, Feisst M, Hölle T, Dugas M, Zental N, Kumar S, Schaack D, Schuster LC, Etheredge M, Dehne S, Michalski C, Probst P, Diener M, Weigand MA, Klotz R, Larmann J.   +17 more
europepmc   +1 more source

Advanced Corneal Hydrogels: From Passive Replacement to Active Regeneration and Intelligent Interaction

Advanced Science, EarlyView.
This review charts the evolution of corneal hydrogels from passive replacements to active and intelligent systems, evaluating natural and synthetic materials while addressing design challenges such as transparency and strength. Advanced applications such as scarless wound healing, three‐dimensional bioprinting, and smart wearables are highlighted to ...
Xinwei Wang, Wen Zhou, Haotian Xue, Wenjun Xue, Guangping Gao, Bing Zhu, Hongyuan Song, Qingqiang Xu, Jing Zhao, Wei Shen   +9 more
wiley   +1 more source

Bridging technology and sustainability: examining the role of green AI adoption in Indian banking sector. [PDF]

Front Artif Intell
Chandran M C S, Chandran R, Achuthan K.
europepmc   +1 more source

Several novel classes of small regulatory RNAs show widespread changes in schizophrenia and bipolar disorder and extensive linkages to critical brain processes. [PDF]

Transl Psychiatry
Nersisyan S, Loher P, Nazeraj I, Shao Z, Fullard JF, Voloudakis G, Girdhar K, Roussos P, Rigoutsos I.   +8 more
europepmc   +1 more source

Regulation and performance of health systems: a review of analytical frameworks. [PDF]

Rev Panam Salud Publica
Báscolo E, Debrott Sánchez D, Houghton N, Vance C.   +3 more
europepmc   +1 more source

Epstein-Barr Virus Promotes Gastric Cancer Progression by Modulating m6A-Dependent YTHDF1-TSC22D1 Axis. [PDF]

Microorganisms
An YR, Jung J, Kwon KM, Kim JY, Lee MH, Lee JY, Lee M, Lee SK.   +7 more
europepmc   +1 more source

Elevated Na⁺/K⁺ Ratio in Alzheimer's Disease: A Potential Biomarker for Braak Stage. [PDF]

Int J Mol Sci
Mizuno Y, Pan S, Zhou T, Kehoe PG, Feng Earley Y.   +4 more
europepmc   +1 more source

Differential expression of long non-coding RNA in the hypothalamus-pituitary-gonadal axis of Wanxi white geese during laying and broodiness periods. [PDF]

Anim Biosci
Li X, Hou M, Wang Y, Wu F, Tong X, Xie F, Jiang C, Jin M, Ren M, Li S.   +9 more
europepmc   +1 more source