Results 41 to 50 of about 1,237,302 (315)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Credit Risk Assessment of Legal Customers using Financial and Performance Indicators (Case: Bank Mellat of East Azarbaijan Province) [PDF]

مطالعات مالی و بانکداری اسلامی, 2016
Risk assessment is one of the main concerns of commercial banks when granting loans. Although there are several methods including financial ratios to assess the credit risk of customers, the aim of this article  is to apply several financial and ...
Eldar Sedaghatparast, Siavash Golzarianpour, Hasan Ghaffari Ghazani   +2 more
doaj  

FEATURES OF FUNCTIONING NATIONAL MODEL OF RESOURCE ECONOMICS IN UKRAINE

Фінансово-кредитна діяльність: проблеми теорії та практики, 2018
Introduction. Almost thirty years in the modern history of Ukraine were marked by modest economic and social outcomes. Extremely low rates of economic growth, price and exchange rate instability, technological backwardness of the majority of domestic ...
Serhii Kolodii, Inna Kochuma, Anatoly Marenych, Mykola Rudenko   +3 more
doaj   +1 more source

Default Risk On Islamic Banking In Indonesia [PDF]

, 2014
Stability of financial institutions is a crucial issue amid the economic crisis that hit the US and Europe. Islamic banking in Indonesia as financial institutions are also required to have good stability in order to maintain the stability of the national
Ardiansyah, M. (Misnen), Fauzi, A. S. (Ahmad), Munandar, A. (Aris), Naimah, U. (Ulufun)   +3 more
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

In the Shadow of the Golden Calf.

Jahrbuch für Wirtschaftsgeschichte, 2022
The article offers the first comprehensive account of relations between Germany and Switzerland in the years 1919 to 1931 based on archival sources from both countries.
Farquet Christophe
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Competitiveness Ability Model in E-Banking [PDF]

کاوش‌های مدیریت بازرگانی, 2019
The aim of this study was to identify the indicators of competitive ability in an electronic banking system. To conduct the research, a qualitative method and semi-structured interviews were used.
Seyed Mohammad Reza Hoseinipour, Mohammad Mahdi Parhizgar, Mirza Hasan Hoseini, Ali Akbar Jowkar   +3 more
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source