Results 51 to 60 of about 1,247,076 (295)

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

The Impact of Fintech on Financial Institutions: The Case of Georgia

open access: yesTalTech Journal of European Studies, 2022
Using Georgia as an example, this article analyses the fintech ecosystem and the impact of fintech companies on traditional financial institutions. Both qualitative and qualitative research has been carried out for this research. Based on the analysis of
Lashkhi Mariam   +3 more
doaj   +1 more source

Application of artificial intelligence in managing customer loyalty in banks

open access: yesInformaciâ i Innovacii, 2023
“Artificial intelligence” (AI) is increasingly mentioned in various fields. The increase in data, along with breakthroughs in storage and computing technologies in computer hardware, is making AI applications more scalable and efficient.
Thi Quyen Do
doaj   +1 more source

Good Banks and bad Banks, centralised Banks and local Banks and economic Growth

open access: yesEkonomiaz. Revista vasca de Economía, 2013
The on-going banking crisis has demonstrated the significance of banking for economic growth. While banks as creators of money are important for the functioning of the economy, bank lending to productive enterprises is necessary for economic activity.
Chick, Victoria   +2 more
openaire   +2 more sources

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

The Impact of Education on Energy Poverty: Empirical Evidence from Vietnam

open access: yesECONOMICS
In the era of industrialization and modernization, energy is always a key factor in creating a breakthrough. In contrast to the constantly increasing demand for energy, shortages or “energy poverty” are increasingly widespread.
Duong Truong Thi Thuy   +5 more
doaj   +1 more source

THE INFLUENCE OF DIGITALIZATION ON CO2 EMISSIONS IN DEVELOPING COUNTRIES: POLICY INSIGHTS FOR VIETNAM

open access: yesTạp chí Khoa học Đại học Đà Lạt
Digital technology has become an unstoppable progression in most countries due to its vital role in socio-economic progress. Meanwhile, humanity is grappling with severe weather events such as superstorms, floods, and rising sea levels caused by ...
Van Bon Nguyen   +5 more
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, Volume 20, Issue 6, Page 1591-1611, June 2026.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Assessing the Influence of Islamic Banks' Products' Quality Features on Customer Satisfaction in Nigeria [PDF]

open access: yes, 2018
Islamic banking is essential in today’s competitive banking markets. Research in Islamic banking worldwide is focussed mainly on how distinct is Islamic banking from the conventional banking.
Baba, Bashir   +2 more
core   +2 more sources

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