Results 61 to 70 of about 3,193,155 (387)

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

FEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom, Jaewoong Jang, Jung Sun Park, Yong‐Kook Kang   +3 more
wiley   +1 more source

A Stringy Correspondence Principle in Cosmology

, 2006
We study a d-dimensional FRW universe, containing a perfect fluid with p = w \rho and \frac{1} {d - 1} \le w \le 1, and find a correspondence principle similar to that of Horowitz and Polchinski in the black hole case.
Banks, Banks, Banks, Banks, Banks, Banks, Banks, Bousso, Bousso, Bousso, Bowick, Bowick, Bowick, Damour, Fischler, Halyo, Halyo, Horowitz, Horowitz, Horowitz, Khuri, Khuri, Khuri, Peet, Rama, S. Kalyana Rama, Susskind, Susskind, Susskind, Veneziano, Veneziano, Weinberg   +31 more
core   +2 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Tenors Not Sopranos: Bio-Mechanical Constraints on Calling Song Frequencies in the Mediterranean Field-Cricket

Frontiers in Ecology and Evolution, 2021
Male crickets and their close relatives bush-crickets (Gryllidae and Tettigoniidae, respectively; Orthoptera and Ensifera) attract distant females by producing loud calling songs.
Thorin Jonsson, Fernando Montealegre-Z, Carl D. Soulsbury, Daniel Robert   +3 more
doaj   +1 more source

Merging: Contemplations on Farming & Ecology from Horseback by Soren Bondrup-Nielsen [PDF]

, 2015
Anna Banks reviews Merging: Contemplations on Farming & Ecology from Horseback, by Soren Bondrup ...
Banks, Anna
core   +1 more source

Tree-structured complementary filter banks using all-pass sections [PDF]

, 1987
Tree-structured complementary filter banks are developed with transfer functions that are simultaneously all-pass complementary and power complementary.
Mitra, Sanjit K., Neuvo, Yrjö, Regalia, Phillip A., Renfors, Markku K., Vaidyanathan, P. P.   +4 more
core   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Banking Crises

, 2008
The current global financial crisis grew out of banking losses in the United States related to subprime lending. How well do economists understand the origins of such crises and how they spread? Was this crisis something new or a replay of familiar historical phenomena? Will policy interventions be able to mitigate its costs?
openaire   +3 more sources

Modelling Systemically Important Banks vis-à-vis the Basel Prudential Guidelines [PDF]

, 2021
M. Zulkifli Salim, Kevin Daly
openalex   +1 more source

The Politician and his Banker [PDF]

, 2007
Should the European Union grant state aid through an institution like the European Investment bank? This paper evaluates the efficiency of different measures for granting state aid.
Hainz, Christa, Hakenes, Hendrik
core   +4 more sources