Results 151 to 160 of about 2,356,155 (301)

Bench Bar Conference, 2005

open access: yes, 2005
Photographs of the Lackawanna Bar Association's annual Bench Bar Conference, held at Marywood University.
Connors, Terry
core   +1 more source

Bulletin, State Bar of Texas, Volume 1, Number 3, December, 1963

open access: yes, 1963
Bulletin of the State Bar of Texas, Vol. 1, No. 3, December 1963. Discussions on the proposed revisions of the Cannons of Ethics. The bulletin has been sent to John J. Herrera with U.S.
State Bar of Texas
core  

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

A tippy path to the bar : an alternative approach

open access: yes, 2011
This paper seeks to achieve two things. First, to provide an analysis of the functions and duties of the modern tipstaff, and, secondly, to explore the question whether undertaking a position as a tipstaff to a judge is useful in preparing for a career ...
Donnelly, Jason (R18560)
core  

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

open access: yesMolecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic   +15 more
wiley   +1 more source

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