Results 201 to 210 of about 61,704 (277)

Steroid anesthetics and naturally occurring analogs modulate the gamma-aminobutyric acid receptor complex at a site distinct from barbiturates.

Journal of Pharmacology and Experimental Therapeutics, 1989
The steroid anesthetic alphaxalone and a series of naturally occurring analogs were compared in potency and efficacy with each other and the hypnotic barbiturate pentobarbital for interaction with gamma-aminobutyric acid (GABA) receptors:binding sites in
D. Turner, R. Ransom, J. Yang, R. Olsen
semanticscholar   +1 more source

Barbiturates: Radioimmunoassay

Science, 1971
The development of a radioimmunoassay for barbiturate is described. The barbiturate is made antigenic by coupling it to a protein, bovine gamma globulin. The radioimmunoassay can measure as little as 5 nanograms of barbiturate.
S, Spector, E J, Flynn
openaire   +2 more sources

The role of GABA in the pathophysiology and treatment of anxiety disorders.

Psychopharmacology bulletin
Mechanisms underlying the pathological characteristics of the various anxiety disorders have yet to be fully elucidated. One of the most widely accepted mediators known to play a central role in the pathophysiology of anxiety disorders is the g ...
C. Nemeroff
semanticscholar   +1 more source

BARBITURATES AND DRIVING

Accident Analysis & Prevention, 1976
Barbiturates are general nervous system depressants which are commonly used as sedatives and hypnotics. Approximately 4% of the adult population, 12% of high school students and 19% of college students have reported using barbiturates. The lack of controlled studies comparing barbiturate involvement in traffic accidents and in the at-risk population ...
openaire   +1 more source

Structure-pharmacokinetic relationships among the barbiturates in the rat.

Journal of Pharmacology and Experimental Therapeutics, 1983
The pharmacokinetics of a congeneric series of barbituric acids were determined after i.v. administration of individual barbiturates or multicomponent barbiturate mixtures to chronically cannulated male rats.
S. Toon, M. Rowland
semanticscholar   +1 more source

The Role of Barbiturates for Alcohol Withdrawal Syndrome.

Psychosomatics, 2016
K. Martin, Andrew Katz
semanticscholar   +1 more source

High-Dose Barbiturates for Refractory Intracranial Hypertension in Children With Severe Traumatic Brain Injury*

Pediatric Critical Care Medicine, 2013
S. Mellion, K. Bennett, German L. Ellsworth, K. Moore, J. Riva‐Cambrin, R. Metzger, S. Bratton   +6 more
semanticscholar   +1 more source

BARBITURATE ASSAY

The Lancet, 1971
D, Watson, G, Dillion
openaire   +4 more sources

Barbituric Acids

Journal of the American Pharmaceutical Association (Scientific ed.), 1953
R B, MOFFETT, J E, STAFFORD, C A, HART
openaire   +2 more sources

N-substituted homopiperazine barbiturates as gelatinase inhibitors.

Bioorganic & Medicinal Chemistry, 2011
Jun Wang, C. Medina, M. Radomski, J. Gilmer   +3 more
semanticscholar   +1 more source