Results 111 to 120 of about 71,936 (305)

A Biofabricated Human Acinus‐on‐a‐Chip Unveils Mechanotransductive Drivers of Ventilator‐Induced Lung Injury via Decoupling Volutrauma and Barotrauma

open access: yesAdvanced Science, EarlyView.
This bioinspired acinus‐on‐a‐chip recapitulates VILI pathology, revealing that volutrauma drives P53/NF‐κB pathways while barotrauma triggers mitochondrial‐Wnt dysregulation. A fibrotic transitional cell cluster was identified. Pharmacological interventions targeting these pathways significantly ameliorated injury, establishing a mechanobiological ...
Heng Lu   +10 more
wiley   +1 more source

DNA Barcoding for CUREs Workshop - 2021

open access: yes, 2023
A 5-day workshop devoted to implementing DNA Barcoding Course-based Undergraduate Research Experiences ...
Ray Enke   +7 more
core   +2 more sources

Fzd7 Restrains Pink1‐Dependent Mitophagy in Suture Stem Cells to Maintain Cranial Suture Patency

open access: yesAdvanced Science, EarlyView.
How suture stem cells fail to preserve cranial suture patency remains incompletely understood. Integrated single‐cell and high‐resolution spatial transcriptomic analyses identify reduced Fzd7 expression in Prrx1+ suture stem cells as an early feature of craniosynostosis.
Xinyan Chen   +10 more
wiley   +1 more source

Environmental barcoding Lusatian Neisse/Odra River

open access: yes, 2014
Environmental barcoding Lusatian Neisse/Odra ...
Zimmermann, Jonas   +9 more
core   +1 more source

Uncoupling Type I Interferon Benefits From Inflammatory Toxicity: Transformer‐Prioritized Precision Agonists for Potent and Safer Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
A Transformer‐based AI framework, DLINP, screens millions of compounds to identify Co68, a cobalt‐pincer organometallic complex that biases TLR4‐MD2 signaling toward antitumor interferon activation while suppressing inflammatory toxicity through an early TLR4‐SYK‐STAT1 axis.
Xuefei Guo   +10 more
wiley   +1 more source

Combining DNA Barcoding and Macroinvertebrate Sampling to Assess Water Quality [PDF]

open access: yes, 2008
DNA barcoding (using a standardized sequence of the mitochondrial CO1 gene) was used to determine the aquatic insect species richness of two sites along White Clay Creek in Pennsylvania.
Dapkey, Tanya
core  

Synthetic DNA barcodes identify singlets in scRNA-seq datasets and evaluate doublet algorithms

open access: yesCell Genomics
Summary: Single-cell RNA sequencing (scRNA-seq) datasets contain true single cells, or singlets, in addition to cells that coalesce during the protocol, or doublets.
Ziyang Zhang   +9 more
doaj   +1 more source

Compact 9dBEs Enable Efficient and Precise Genome Editing in Mammalian Cells and In Vivo

open access: yesAdvanced Science, EarlyView.
As a compact type II‐D system, the Cas9d‐based platform holds great potential for in vivo applications. Through rational engineering, its derived base editors (9dBEs) enable efficient disease modeling while facilitating single‐vector AAV delivery for in vivo genome editing. These miniature tools offer a robust strategy for basic research and biomedical
Qingquan Xiao   +12 more
wiley   +1 more source

Dna Barcoding Library Database Of Aquilaria Member And Gyrinops Member

open access: yes, 2020
Aquilaria and Gyrinops are the primary agarwood producer on International trade. For authentication and standardization purposes, it is essential to carry DNA barcoding studies of these genera.
Wangiyana, I. G. (I)
core  

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