Results 111 to 120 of about 62,315 (312)

Liquid Metal Nanotransformers for Drug‐Resistant Pan‐Cancer Therapy in Patient‐Derived Organoids

Advanced Science, EarlyView.
Pan‐cancer therapies are severely limited in drug‐resistance patients due to genetic mutations and other factors, resulting in poor therapeutic outcomes and constrained clinical benefit. Liquid metal nanotransformers, a new class of shape‐transformable nanomaterials capable of dramatic morphological changes, offer a promising physical strategy to ...
Xiaojie Yuan, Xuelin Wang, Zhongyao Chen, Shuo Wang, Weining Gao, Ziyi Chen, Runyang Li, Cheng Hao, Lei Zhang, Qiongqiong Zhang, Ke Zhang, Mei Yu, Qian Liu, Jingxuan Wang, Huiping Li, Simpkins Fiona, Jing Liu, Qiang Liu, Peng Liu, Yawei Hu   +19 more
wiley   +1 more source

Generation of CCR4/CD7 Bispecific CAR‐T Cells Resistant to Fratricide and Exhaustion

Advanced Science, EarlyView.
The applications of CAR T‐cell therapy in T‐cell malignancies face limitations such as fratricide, effector‐cell exhaustion, and antigen‐escape. Herein, we developed fratricide‐ and exhaustion‐resistant CAR‐T cells that targeted CCR4 and CD7 simultaneously, with optional EGFRt safety switch. Additionally, scRNA‐seq unveiled new molecular targets, which
Sile Li, Yuanxin Li, Asif Rashid, Hong Kee Tan, Shing Chan, Man Yan Hui, Wilson Yau Ki Chan, Kee See Lam, Yinping Liu, Wenwei Tu, Wing Leung   +10 more
wiley   +1 more source

Identification of an experimental protocol for the DNA barcoding of plants from the Padua Botanical Garden applicable in educational contexts

, 2023
openL’oggetto di questo elaborato sperimentale è parte di un più ampio progetto dell’Orto Botanico dell’Università degli Studi di Padova il cui scopo ultimo è l‘identificazione e la classificazione delle piante ad oggi presenti al suo interno ...
VACCARI, PAOLO
core  

DNA barcoding, forensics, and application of DNA chip technology

, 2010
Among the 1,121 recognized fish species in Korean waters, approximately 9% (12 Elasmobranchii and 88 Actinopterygii species) have been barcoded with regards to the COI sequences. The DNA barcodes have been used for investigation of correctness in species
이유철, 이강현, 김고은, 김성, 강미혜, Habib, 배세진, Seung Yong Hwang, 정다금, 오지나, 이윤호   +10 more
core   +1 more source

β‐Elemene Rescues Radiation‐Induced Enteritis by Orchestrating a Host‐Microbiome Circuit That Fuels Epigenetic DNA Repair

Advanced Science, EarlyView.
This study elucidates that β‐elemene promotes cellular uptake of L. gasseri‐derived lactate by enhancing the membrane translocation of MCT1 in a CD147‐dependent manner. Intracellular lactate, through the lactylation of RBBP4 at the K26 site, recruits EP300 to the promoter regions of downstream genes (POLD1/POLD3), catalyzing H3K27ac modification.
Jiancheng He, Jiapeng Bao, Shukang Deng, Weijie Zang, Haoming Yan, Zihao Zhao, Guangze Zhang, Ruiqing Liu, Junjie Chen, Yilin Hu, Wanjiang Xue   +10 more
wiley   +1 more source

Checklist of the genus Cortinarius in Romania: taxonomic and distributional insights

Studia Universitatis Babeș-Bolyai. Biologia
The genus Cortinarius is one of the most diverse ectomycorrhizal lineages of Basidiomycota, yet its diversity in Romania has remained poorly documented.
Emerencia Szabó, Avar-Lehel Dénes, Róbert Veres, Bálint Dima, Lujza Keresztes   +4 more
doaj   +1 more source

Single‐Cell Dissection of Tumor‐Infiltrating Lymphocytes Reveals Cellular Architecture Predictive of Therapeutic Efficacy in Acral Melanoma

Advanced Science, EarlyView.
Autologous tumor‐infiltrating lymphocyte (TIL) therapy shows promising efficacy in acral melanoma, yet determinants of durable response remain unclear. By integrating single‐cell transcriptomics and TCR sequencing, this study reveals that TIL products enriched for T follicular helper and intermediate exhausted T cells establish persistent clonal ...
Chao Zhang, Wanyi Xiao, Hongru Shen, Fenge Li, Ting Li, Weihong Zhang, Haotian Liu, Ziwei Gao, Hongyu Wang, Xiubao Ren, Kexin Chen, Xiangchun Li, Jilong Yang   +12 more
wiley   +1 more source

DNA Barcoding of Lichenized Fungi Demonstrates High Identification Success in a Floristic Context

, 2011
DNA Barcoding of Lichenized ...

core  

Potential efficacy of mitochondrial genes for animal DNA barcoding: a case study using eutherian mammals

, 2011
Background A well-informed choice of genetic locus is central to the efficacy of DNA barcoding. Current DNA barcoding in animals involves the use of the 5' half of the mitochondrial cytochrome oxidase 1 gene (CO1) to diagnose and delimit species. However,
Cameron Stephen L, Zhu, Chaodong, Shi Weifeng, Zhang Aibing, Xu Weijun, Weifeng Shi, Ho, Simon, Yanzhou Zhang, Aibing Zhang, Luo Arong, Xu, Weijun, Zhang, Yanzhou, Zhang Yanzhou, Zhu Chaodong, Shi, Weifeng, Luo, A-Rong, Ho Simon YW, Arong Luo, Stephen L Cameron, Zhang, Aibing, Cameron, Stephen, Simon YW Ho, Weijun Xu, Chaodong Zhu   +23 more
core   +1 more source

DNA barcoding data

, 2019
Seed-deposition samples (bird droppings with seeds, defecated or regurgitated) analysed through DNA barcoding to identify the bird species responsible of seed dispersal events.
Sarah Díaz-García (6833261), Arroyo, Juan M., Jordano, Pedro, Juan M. Arroyo (3267360), Pedro Jordano (42324), González-Varo, Juan P., Díaz-García, Sarah, Juan P. González-Varo (8026256)   +7 more
core   +2 more sources