Results 121 to 130 of about 62,315 (312)

Comparative Oligo‐FISH Mapping Illuminates Chromosomal Evolution Among Rutaceae Species Diverged Over 50 Million Years

Advanced Science, EarlyView.
Oligonucleotide‐based fluorescence in situ hybridization probes were developed in the model citrus species Citrus maxima. These probes were applied to comparative karyotyping across 14 species in the Rutaceae family. This analysis revealed chromosomal evolution in lineages that diverged from Citrus nearly 52 million years ago.
Li He, Hainan Zhao, Xiaoxue Zeng, Zujun Yang, Wenting Li, Guoyan Zhang, Guangrong Li, Jian He, Bin Guan, Jiming Jiang   +9 more
wiley   +1 more source

DNA Replication Errors Drive Genome‐Wide Small Inverted Triplication Dynamics

Advanced Science, EarlyView.
This study provides insight into the dynamic equilibrium mechanism of a novel structural variant, small inverted triplication (SIT), which is generated by misalignment of the 3’ flap generated under DNA replication stress with palindromic sequence. Alternatively, the end sequence may fold back on itself to form an inverted fragment.
Yi Lei, Yu Zhou, Haitao Sun, Hang Yuan, Xinyu Pei, Jessica D. Hess, Yao Yan, Zunsong Hu, Mian Zhou, Zhaohui Gu, Li Zheng, Xiwei Wu, Binghui Shen   +12 more
wiley   +1 more source

Synthetic DNA barcodes identify singlets in scRNA-seq datasets and evaluate doublet algorithms

Cell Genomics
Summary: Single-cell RNA sequencing (scRNA-seq) datasets contain true single cells, or singlets, in addition to cells that coalesce during the protocol, or doublets.
Ziyang Zhang, Madeline E. Melzer, Keerthana M. Arun, Hanxiao Sun, Carl-Johan Eriksson, Itai Fabian, Sagi Shaashua, Karun Kiani, Yaara Oren, Yogesh Goyal   +9 more
doaj   +1 more source

A Circuit of Mechanically Regulated Transcription Factors Balances Regenerative and Fibrotic Memory of Mesenchymal Stromal Cells

Advanced Science, EarlyView.
Producing MSCs on rigid culture substrates induces a scar‐making phenotype, jeapordizing therapeutic success. ‘Tissue‐soft’ surfaces prevent MSC fibrogenesis and preserve regenerative traits. An epigenetic network, driven by HOXA11 and SALL1, maintains ‘soft memory’ by keeping chromatin open in relaxed MSCs, promoting anti‐fibrotic programs.
Fereshteh Sadat Younesi, Andrew E. Miller, Li Diao, Xinying Guo, Natalie Andonian, Elham Karimizadeh, Thomas H. Barker, Boris Hinz   +7 more
wiley   +1 more source

Using molecular tools to differentiate closely related blackfly species of the genus Simulium

, 2008
Biodiversity data are the foundation for conservation and managemet and taxonomy provides the reference system, skills and tools used to identify organisms.
Day, J.C., Day, J. C.
core  

RBM10 Deficiency Promotes Anti‐PD‐1 Resistance in LUAD via STING Alternative Splicing‐Driven CCL7 Signaling and Macrophage Polarization

Advanced Science, EarlyView.
RBM10 deficiency promotes anti‐PD‐1 resistance in lung adenocarcinoma by altering STING alternative splicing, which enhances CCL7 secretion and CCR2‐dependent M2 macrophage polarization. A positive feedback loop via mitochondrial transfer sustains this immunosuppression.
Weitong Gao, Ruqiong Wang, Bo An, Lishuang Qi, Zihan Jing, Xingmei Ren, Yang Zhou, Mingjun Xu, Jiaojiao Li, Jie Liu, Liying Wang, Gang Xu, Rou Li, Dexin Jia, Yan Yu   +14 more
wiley   +1 more source

THE DNA BARCODING METHOD AND ITS APPLICATIONS IN THE FOOD INDUSTRY: FROM FRAUD DETECTION TO FOOD SAFETY AND TRACEABILITY

, 2023
reservedIL DNA BARCODING È UN METODO DI IDENTIFICAZIONE MOLECOLARE CHE PREVEDE L’UTILIZZO DI BREVI SEQUENZE DI DNA, PROVENIENTI DA UNO O PIÙ GENI SPECIFICI, PER IDENTIFICARE IN MODO UNIVOCO UNA SPECIE.
PIGNAT, FRANCESCA
core  

Autonomous reef monitoring structures as a tool for assessing UK marine benthic biodiversity

Frontiers in Marine Science
In benthic marine ecosystems, small organisms that dwell within the habitat matrix comprise the majority of species richness but are inherently difficult to sample. This limits our ability to document the biodiversity of these ecosystems. Autonomous Reef
Michael Jordan, Margaux Steyaert, Natalie Y.N. Ng, Kevin Hopkins, Raymond D. Ward, Raymond D. Ward, Chris Yesson, Emma Ransome   +7 more
doaj   +1 more source

Two Routes to Land: Genomic Underpinnings of Parallel Aerial Egg Deposition in Aquatic Old‐World Pila and New‐World Pomacea (Ampullariidae)

Advanced Science, EarlyView.
Comparative genomics of Gondwana‐diverged Pila and Pomacea reveals parallel evolution of aerial oviposition. Convergent chromosomal rearrangements reshape regulatory landscapes within topologically associating domains. Lineage‐specific gene family expansions and viral‐derived perivitelline proteins (PV1) underpin desiccation resistance.
Yufei Zhou, Huawei Mu, Xueying Nie, Yue Gao, Hui Wang, Ling Fang, Tiangang Luan, Monthon Ganmanee, Jian‐Wen Qiu, Jin Sun, Jack Chi‐Ho Ip   +10 more
wiley   +1 more source

DNA barcoding of phytoplasmas

, 2012
Phytoplasmas infect a high number of plant species. Based on the 16S ribosomal gene sequence, over 20 RFLP groups have been established within the ‘Candidatus Phytoplasma’ taxon, some of which are of quarantine status.
CONTALDO, NICOLETTA, PALTRINIERI, SAMANTA, Nicolaisen M., BERTACCINI, ASSUNTA, O. Makarova   +4 more
core