Results 81 to 90 of about 1,788,349 (198)

Age‐related loss of hysteresis in the spontaneous vascular sympathetic baroreflex is associated with altered neural rather than mechanical control

Experimental Physiology, EarlyView.
Abstract The vascular sympathetic baroreflex is critical for stabilising blood pressure. A notable feature of this reflex is hysteresis, a directional asymmetry in responsiveness during rising versus falling pressure that is evident in young adults but attenuated in older age.
Guto Wyn Hughes, Denis J. Wakeham, Christopher J. A. Pugh, Zoe H. Adams, Rachel N. Lord, Jonathan P. Moore   +5 more
wiley   +1 more source

Comparison in conscious rabbits of the baroreceptor-heart rate reflex effects of chronic treatment with rilmenidine, moxonidine, and clonidine

Frontiers in Physiology, 2016
We investigated the effects of chronic subcutaneous treatment with centrally-acting antihypertensive agents moxonidine, rilmenidine and clonidine on the baroreflex control of heart rate (HR) in conscious normotensive rabbits over 3 weeks.
Monique L Parkin, Kyungjoon Lim, Sandra L Burke, Geoffrey A Head   +3 more
doaj   +1 more source

Comparison of exercise training and repeated hot water immersion on vascular function in overweight older adults

Experimental Physiology, EarlyView.
Abstract Recent studies suggest that heat exposure may benefit cardiovascular health, but in overweight and obese older adults, the chronic effects of heat therapy on artery function are still uncertain. We aimed to compare the effects of 12 weeks (3×/week, 40 min) of aerobic exercise (EXE) to hot water immersion (HWI) and an inactive control group ...
Juliene G. Costa, Joao Carlos Locatelli, Kristanti W. Wigati, Louise H. Naylor, Helen Jones, Andrew Haynes, Daniel J. Green   +6 more
wiley   +1 more source

Pulmonary arterial mechanoreceptors modulate exercise‐induced sympathetic activation in healthy humans during moderate‐intensity hypoxic exercise

The Journal of Physiology, EarlyView.
Abstract figure legend This randomized cross‐over trial (N = 12) addressed the hypothesis that selective reduction of pulmonary arterial pressure (i.e. manipulation of pulmonary arterial mechanoreceptor activation) during hypoxic exercise would reduce sympathetic outflow (muscle sympathetic nerve activity (MSNA)) in healthy humans.
Michiel T. Ewalts, Thomas D. Griffiths, Andrew J. M. Douglas, Elliott J. Jenkins, Guto Wyn Hughes, Craig D. Steinback, Lydia L. Simpson, Samuel J. Oliver, Mike Stembridge, Jonathan P. Moore   +9 more
wiley   +1 more source

Mechanisms of haemoglobin mass expansion following heat stress

The Journal of Physiology, EarlyView.
Abstract figure legend Theorised mechanisms of heat stress‐induced erythropoiesis which may facilitate the expansion of haemoglobin mass. A, acute: heat stress‐induced renal ischaemia. Redistribution of blood flow away from the kidneys to facilitate thermoregulation during heat stress could reduce renal oxygen delivery, subsequently lowering renal PO2${
Elliott J. Jenkins, Brittany A. Edgett, Michael G. Hughes, Joshua C. Tremblay, Mike Stembridge   +4 more
wiley   +1 more source

Effects of acetylstrophanthidin on baroreflex sensitivity in patients with acute myocardial infarction

, 1993
We evaluated the effects of acetylstrophanthidin on baroreflex sensitivity in patients soon after an acute myocadial infarction. Baroreflex control of heart rate is frequently depressed after acute myocardial infarction and few data are available as to ...
Carpinelli A., Bianchi V, PETRETTA, MARIO, Valva G, Themistoclakis S, Rotondi F, Morgano G, BONADUCE, DOMENICO   +7 more
core   +1 more source

Cannabinoid exposure during pregnancy: Cardiorespiratory effects and offspring outcomes

The Journal of Physiology, EarlyView.
Abstract figure legend Prenatal exposure to cannabinoids has been investigated across human and animal studies to understand its impact on physiological development. Evidence suggests that early‐life cannabinoid exposure influence multiple developmental processes, extending beyond neurodevelopmental outcomes to potentially affect placental function ...
Luis Gustavo A. Patrone, Luciane H. Gargaglioni   +1 more
wiley   +1 more source

Baroreceptor stimulation: Pain perception and sensory thresholds [PDF]

, 1994
Baroreceptor activity has been implicated in the modulation of pain. Sensory detection thresholds and pain ratings were measured in a group of 28 men during carotid baroreceptor manipulation with the PRES (phase-related external suction) neck suction ...
Roskamm, H., Droste, C., Rau, Harald K., Brody, S., Roskamm, Helmut, Greenlee, Mark W., Droste, Conrad, Kardos, A., Rau, H., Kardos, Attila, Brody, Stuart   +10 more
core   +1 more source

The influence of haemoglobin–O2 affinity on aerobic capacity in hypoxia in high‐altitude deer mice (Peromyscus maniculatus)

The Journal of Physiology, EarlyView.
Abstract figure legend The influence of haemoglobin–O2 affinity on aerobic capacity in hypoxia has been contentious. Many high‐altitude natives have greater haemoglobin–O2 affinity (lower P50, the O2 pressure at 50% haemoglobin saturation) than their low‐altitude counterparts, but the advantages of this change for aerobic metabolism have often remained
Kayla M. Garvey, Graham R. Scott
wiley   +1 more source

Role of reactive oxygen species in mediating peripheral hypoxic vasodilation and sympathoexcitation at high altitude

The Journal of Physiology, EarlyView.
Abstract figure legend High‐altitude acclimatisation increases muscle sympathetic nerve activity (MSNA) via activation of the arterial chemoreflex, pulmonary arterial baroreceptors and resetting of the sympathetic vascular baroreflex. However attempting to silence these mechanisms only partially normalises MSNA, implicating other contributory ...
Liam D. Corr, Andrew J. M. Douglas, Elliott J. Jenkins, Lauren E. Maier, Jodie L. Koep, Travis D. Gibbons, Adam Field, James D. Anholm, Katharine Foster, Zoe H. Adams, Lydia L. Simpson, Jonathan P. Moore, Tinna Traustadottir, Christoph Siebenmann, Joshua C. Tremblay, Mike Stembridge   +15 more
wiley   +1 more source