Results 21 to 30 of about 12,500 (179)

Developing a Ministroke Model in Mouse Barrel Cortex. [PDF]

open access: yesBio Protoc
Stroke is a worldwide leading cause of death and long-term disability, with ischemic strokes making up approximately 85% of all cases. There is a significant need for an ideal animal model that accurately replicates the disease's pathology to study the molecular mechanisms of brain injury.
Wang S   +8 more
europepmc   +4 more sources

Lhx2 Expression in Postmitotic Cortical Neurons Initiates Assembly of the Thalamocortical Somatosensory Circuit

open access: yesCell Reports, 2017
Cortical neurons must be specified and make the correct connections during development. Here, we examine a mechanism initiating neuronal circuit formation in the barrel cortex, a circuit comprising thalamocortical axons (TCAs) and layer 4 (L4) neurons ...
Chia-Fang Wang   +8 more
doaj   +1 more source

Shifts in developmental timing, and not increased levels of experience-dependent neuronal activity, promote barrel expansion in the primary somatosensory cortex of rats enucleated at birth. [PDF]

open access: yesPLoS ONE, 2013
Birth-enucleated rodents display enlarged representations of whiskers (i.e., barrels of the posteromedial subfield) in the primary somatosensory cortex.
Ingrid Fetter-Pruneda   +9 more
doaj   +1 more source

Local Cerebral Blood Flow during the First Hour Following Acute Ligation of Multiple Arterioles in Rat Whisker Barrel Cortex

open access: yesNeurobiology of Disease, 1998
The objectives are to measure the early time-course of the flows of blood, red cells, and plasma in brain tissue destined to infarct following arterial occlusion.
Ling Wei   +7 more
doaj   +1 more source

Texture coarseness responsive neurons and their mapping in layer 2–3 of the rat barrel cortex in vivo

open access: yeseLife, 2014
Texture discrimination is a fundamental function of somatosensory systems, yet the manner by which texture is coded and spatially represented in the barrel cortex are largely unknown.
Liora Garion   +6 more
doaj   +1 more source

Associations of unilateral whisker and olfactory signals induce synapse formation and memory cell recruitment in bilateral barrel cortices: cellular mechanism for unilateral training toward bilateral memory

open access: yesFrontiers in Cellular Neuroscience, 2016
Somatosensory signals and operative skills learned by unilateral limbs can be retrieved bilaterally. In terms of cellular mechanism underlying this unilateral learning toward bilateral memory, we hypothesized that associative memory cells in bilateral ...
Zilong Gao   +14 more
doaj   +1 more source

Deconstructing the Cortical Column in the Barrel Cortex [PDF]

open access: yesNeuroscience, 2018
The question of what function is served by the cortical column has occupied neuroscientists since its original description some 60years ago. The answer seems tractable in the somatosensory cortex when considering the inputs to the cortical column and the early stages of information processing, but quickly breaks down once the multiplicity of output ...
openaire   +3 more sources

Rapid Fluctuations in Rat Barrel Cortex Plasticity [PDF]

open access: yesThe Journal of Neuroscience, 2004
Neuronal populations in the sensory cortex exhibit fluctuations in excitability, and the present experiments tested the hypothesis that these variations coincide with peaks and troughs in cortical modifiability. The activity of multiunit neuronal clusters under light urethane anesthesia was recorded through 100-microelectrode arrays implanted in the ...
Erchova, IA, Diamond, ME
openaire   +3 more sources

Deficits in Behavioral Functions of Intact Barrel Cortex Following Lesions of Homotopic Contralateral Cortex

open access: yesFrontiers in Systems Neuroscience, 2018
Focal unilateral injuries to the somatosensory whisker barrel cortex have been shown cause long-lasting deficits in the activity and experience-dependent plasticity of neurons in the intact contralateral barrel cortex.
Rahul Chaudhary, V. Rema
doaj   +1 more source

Upregulation of excitatory neurons and downregulation of inhibitory neurons in barrel cortex are associated with loss of whisker inputs

open access: yesMolecular Brain, 2013
Loss of a sensory input causes the hypersensitivity in other modalities. In addition to cross-modal plasticity, the sensory cortices without receiving inputs undergo the plastic changes.
Zhang Guanjun   +4 more
doaj   +1 more source

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