Results 1 to 10 of about 5,007,964 (396)

Establishment of an in vitro model of cultured viable human, porcine and canine skin and comparison of different media supplements [PDF]

PeerJ, 2019
Transdermal drug delivery provides several advantages over conventional drug administration, such as the avoidance of first-pass metabolism and better patient compliance.
Isa Bauhammer, Manuel Sacha, Eleonore Haltner   +2 more
doaj   +2 more sources

A year in review: brain barriers and brain fluids research in 2022

Fluids and Barriers of the CNS, 2023
This aim of this editorial is to highlight progress made in brain barrier and brain fluid research in 2022. It covers studies on the blood-brain, blood-retina and blood-CSF barriers (choroid plexus and meninges), signaling within the neurovascular unit ...
Richard F. Keep, H. Jones, Mark G. Hamilton, Lester R. Drewes   +3 more
semanticscholar   +1 more source

Experimental hepatic encephalopathy causes early but sustained glial transcriptional changes

Journal of Neuroinflammation, 2023
Hepatic encephalopathy (HE) is a common complication of liver cirrhosis, associated with high morbidity and mortality, for which no brain-targeted therapies exist at present.
Wouter Claeys, Lien Van Hoecke, Hannah Lernout, Clint De Nolf, Griet Van Imschoot, Elien Van Wonterghem, Daan Verhaege, Jonas Castelein, Anja Geerts, Christophe Van Steenkiste, Roosmarijn E. Vandenbroucke   +10 more
doaj   +1 more source

Delivery of RNA to the Blood-Brain Barrier Endothelium Using Cationic Bicelles

Pharmaceutics, 2023
Blood-brain barrier (BBB) dysfunction is prevalent in Alzheimer’s disease and other neurological disorders. Restoring normal BBB function through RNA therapy is a potential avenue for addressing cerebrovascular changes in these disorders that may lead to
Joan Cheng, Lushan Wang, Vineetha Guttha, Greg Haugstad, Karunya K. Kandimalla   +4 more
doaj   +1 more source

Barriers and facilitators to the use of e-health by older adults: a scoping review

BMC Public Health, 2021
Limited attention has been paid to how and why older adults choose to engage with technology-facilitated health care (e-health), and the factors that impact on this. This scoping review sought to address this gap.
Jessica L. Wilson, M. Heinsch, D. Betts, D. Booth, F. Kay-Lambkin   +4 more
semanticscholar   +1 more source

COMPARISONS OF THE HISTOLOGICAL MORPHOLOGY AND IN VITRO PERCUTANEOUS ABSORPTION OF CAFFEINE IN SHED SNAKE SKIN AND HUMAN SKIN

Slovenian Veterinary Research, 2020
The employment of excised skin (human or animal) mounted in diffusion cells is frequently used for the characterization of biopharmaceutical properties of topical semisolids dosage forms.
Manuel Sacha, Nancy Weisbach, Anna-Sophie Pöhler, Nina Demmerle, Eleonore Haltner   +4 more
doaj   +1 more source

A mouse model of hepatic encephalopathy: bile duct ligation induces brain ammonia overload, glial cell activation and neuroinflammation

Scientific Reports, 2022
Hepatic encephalopathy (HE) is a common complication of chronic liver disease, characterized by an altered mental state and hyperammonemia. Insight into the brain pathophysiology of HE is limited due to a paucity of well-characterized HE models beyond ...
Wouter Claeys, Lien Van Hoecke, Anja Geerts, Hans Van Vlierberghe, Sander Lefere, Griet Van Imschoot, Elien Van Wonterghem, Bart Ghesquière, Roosmarijn E. Vandenbroucke, Christophe Van Steenkiste   +9 more
doaj   +1 more source

Blood–brain barrier disruption in atrial fibrillation: a potential contributor to the increased risk of dementia and worsening of stroke outcomes?

Open Biology, 2021
Atrial fibrillation (AF) has become one of the most significant health problems worldwide, warranting urgent answers to currently pending questions on the effects of AF on brain function.
Ritambhara Aryal, Adjanie Patabendige
doaj   +1 more source

Planet Texas 2050 Shares Support for Austin Climate Equity Plan [PDF]

, 2020
You are viewing an article about Planet Texas 2050 published in November 2020.Office of the VP for ...
Bridging Barriers, UT Austin
core   +1 more source

Mapping the dynamics of insulin-responsive pathways in the blood–brain barrier endothelium using time-series transcriptomics data

npj Systems Biology and Applications, 2022
Critical functions of the blood–brain barrier (BBB), including cerebral blood flow, energy metabolism, and immunomodulation, are regulated by insulin signaling pathways.
Zengtao Wang, Xiaojia Tang, Suresh K. Swaminathan, Karunya K. Kandimalla, Krishna R. Kalari   +4 more
doaj   +1 more source