Results 21 to 30 of about 2,091,453 (310)

Validation and stability analysis of a modified lactate dehydrogenase (LDH) test method to be employed for an in vitro viable skin model

Heliyon, 2019
In view of increasing numbers of dermatological disorders, transdermal drug delivery along with in vitro research is becoming increasingly popular. Herefore, qualified in vitro skin models are required.
I. Bauhammer, M. Sacha, E. Haltner
doaj   +1 more source

Limitations of PLX3397 as a microglial investigational tool: peripheral and off-target effects dictate the response to inflammation

Frontiers in Immunology, 2023
Microglia, the resident macrophages of the central nervous system (CNS), play a critical role in CNS homeostasis and neuroinflammation. Pexidartinib (PLX3397), a colony-stimulating factor 1 (CSF1) receptor inhibitor, is widely used to deplete microglia ...
Wouter Claeys, Wouter Claeys, Wouter Claeys, Wouter Claeys, Daan Verhaege, Daan Verhaege, Griet Van Imschoot, Griet Van Imschoot, Elien Van Wonterghem, Elien Van Wonterghem, Lore Van Acker, Lore Van Acker, Laura Amelinck, Laura Amelinck, Federico F. De Ponti, Federico F. De Ponti, Charlotte Scott, Charlotte Scott, Anja Geerts, Anja Geerts, Anja Geerts, Christophe Van Steenkiste, Christophe Van Steenkiste, Lien Van Hoecke, Lien Van Hoecke, Roosmarijn E. Vandenbroucke, Roosmarijn E. Vandenbroucke   +26 more
doaj   +1 more source

RFP: Year 2 Project Grant Opportunities Announced [PDF]

, 2020
Bridging Barriers writes about Good Systems and their year 2 project grant opportunities on February 2020.Office of the VP for ...
News, UT
core   +1 more source

Perceptions regarding strategic and structural entry barriers [PDF]

, 2009
This article uses factor analysis to identify the underlying dimensions of strategic and structural entry barriers. We find that, in the perception of firms, both types of barriers are important and that the effectiveness of strategic barriers depends on
Dijkstra, S.G., Lutz, C.H.M., Kemp, Ron G. M., Kemp, R.G.M., Ron G. M. Kemp, Dijkstra, S. Gerhard, Clemens H. M. Lutz, S. Gerhard Dijkstra, Lutz, Clemens H. M., Ron Kemp, Clemens Lutz   +10 more
core   +1 more source

Retromer-Mediated Trafficking of Transmembrane Receptors and Transporters

Membranes, 2015
Transport between the endoplasmatic reticulum, the Golgi-network, the endo-lysosomal system and the cell surface can be categorized as anterograde or retrograde, describing traffic that goes forward or backward, respectively.
Stine C. Klinger, Piotr Siupka, Morten S. Nielsen   +2 more
doaj   +1 more source

Calling all Writers! [PDF]

, 2020
You are viewing a news article about Good Systems from 2020.Office of the VP for ...
UT Austin, Bridging Barriers
core   +1 more source

Cerebrospinal fluid dynamics and intracranial pressure elevation in neurological diseases

Fluids and Barriers of the CNS, 2019
The fine balance between the secretion, composition, volume and turnover of cerebrospinal fluid (CSF) is strictly regulated. However, during certain neurological diseases, this balance can be disrupted.
Steven William Bothwell, Damir Janigro, Adjanie Patabendige   +2 more
doaj   +1 more source

Alzheimer’s Disease and Age-Related Changes in the Cu Isotopic Composition of Blood Plasma and Brain Tissues of the APP^NL-G-F Murine Model Revealed by Multi-Collector ICP-Mass Spectrometry

Biology, 2023
Alzheimer’s’ disease (AD) is characterized by the formation of β-amyloid (Aβ) plaques and neurofibrillary tangles of tau protein in the brain. Aβ plaques are formed by the cleavage of the β-amyloid precursor protein (APP).
Kasper Hobin, Marta Costas-Rodríguez, Elien Van Wonterghem, Roosmarijn E. Vandenbroucke, Frank Vanhaecke   +4 more
doaj   +1 more source

Barriers to Entry: Abolishing the Barriers to Understanding [PDF]

Journal of Public Finance and Public Choice, 2009
The concept of a barrier to entry has been discussed least since Bain [1956] with important contributions by Spence [1977], Dixit [1980] and Milgrom - Roberts [1982]. The more recent discussion is synthesized in the contributions to a dedicated session at the 2004 AEA meeting. Yet, a ‘barrier to entry’ remains a surprisingly elusive concept, which even
openaire   +1 more source

Effects of fasudil on blood–brain barrier integrity

Fluids and Barriers of the CNS, 2022
Background Cerebral infarction accounts for 85% of all stroke cases. Even in an era of rapid and effective recanalization using an intravascular approach, the majority of patients have poor functional outcomes.
Kei Sato, Shinsuke Nakagawa, Yoichi Morofuji, Yuki Matsunaga, Takashi Fujimoto, Daisuke Watanabe, Tsuyoshi Izumo, Masami Niwa, Fruzsina R. Walter, Judit P. Vigh, Ana Raquel Santa-Maria, Maria A. Deli, Takayuki Matsuo   +12 more
doaj   +1 more source