Results 81 to 90 of about 5,007,964 (396)
Review of Barriers to Engaging Black and Minority Ethnic Groups in Physical Activity in the United Kingdom [PDF]
, 2009 Introduction and Objective: The lower physical activity levels in Black and Minority Ethnic (BME) groups as compared with general population in the United Kingdom (UK) could relate to barriers to engaging these groups in physical activity.
Koshoedo, Seljo +2 more
core
Cyclic nucleotide signaling as a drug target in retinitis pigmentosa
FEBS Letters, EarlyView.Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää +2 more
wiley +1 more source
Frontiers in Psychology, 2017 Background: New technologies provide opportunities for the delivery of broad, flexible interventions with older adults. Focus groups were conducted to: (1) understand older adults' familiarity with, and barriers to, interacting with new technologies and ...
E. Vaportzis +2 more
semanticscholar +1 more source
FEBS Letters, EarlyView.Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu +17 more
wiley +1 more source
TrkB-enhancer facilitates functional recovery after traumatic brain injury
Scientific Reports, 2017 Brain-derived neurotrophic factor (BDNF), a key player in regulating synaptic strength and learning, is dysregulated following traumatic brain injury (TBI), suggesting that stimulation of BDNF signaling pathways may facilitate functional recovery.
John Marshall +9 more
doaj +1 more source
Acta Medica International, 2020 Introduction: Dementia is a prevalent cause of morbidity and runs a downhill course. Patients progressively become completely dependent on their caregivers who are usually untrained family members.
Avik Kumar Layek +3 more
doaj +1 more source
, 1993 I discuss recent progress in our understanding of two barriers in quantum gravity: $c > 1$ in the case of 2d quantum gravity and $D > 2$ in the case of Euclidean Einstein-Hilbert gravity formulated in space-time dimensions $D >2$.Comment: standard latex,
Ambjorn, Jan
core +2 more sources
Knocking down barriers: advances in siRNA delivery
Nature reviews. Drug discovery, 2009 In the 10 years that have passed since the Nobel prize-winning discovery of RNA interference (RNAi), billions of dollars have been invested in the therapeutic application of gene silencing in humans.
K. Whitehead +2 more
semanticscholar +1 more source
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
FEBS Letters, EarlyView.Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan +2 more
wiley +1 more source
Barriers to participation in vocational orientation programmes among prisoners [PDF]
, 2015 This study investigates the barriers to prisoners’ participation in vocational education, as well as the predictors of different types of barriers. Survey data derived from a project in a remand prison in Belgium (N=468) provided the empirical evidence ...
Brosens, Dorien +3 more
core +3 more sources