Results 61 to 70 of about 1,103,157 (202)
Molecular Genetics &Genomic Medicine, Volume 14, Issue 8, August 2026.This report expands the limited available data on type VIII 3‐methylglutaconic aciduria (MGCA8), a neurodegenerative disorder which involves biallelic pathogenic variants of HTRA2 gene. The mutation of this gene leads to mitochondrial dysfunction and altered apoptosis regulation, especially in the brain.
Barbara Belmessieri +7 more
wiley +1 more source
Cardiac‐specific succinate dehydrogenase deficiency in Barth syndrome
EMBO Molecular Medicine, 2015 Barth syndrome (BTHS) is a cardiomyopathy caused by the loss of tafazzin, a mitochondrial acyltransferase involved in the maturation of the glycerophospholipid cardiolipin.
Jan Dudek +13 more
doaj +1 more source
Orphanet Journal of Rare Diseases, 2021 Background Barth syndrome (BS) is a life-threatening genetic disease caused by abnormal lipids in the mitochondria of cells and mostly affects young males.
Aidan Searle +5 more
doaj +1 more source
Mitochondrial membrane remodeling in stress adaptation: Lipid control of organelle quality
Protein Science, Volume 35, Issue 8, August 2026.Abstract Mitochondria respond to proteotoxic stress through the mitochondrial unfolded protein response, traditionally viewed as a transcriptional program that restores proteostasis by inducing chaperones and proteases. Emerging evidence indicates that mitochondrial membrane remodeling constitutes an additional adaptive component of this response ...
Lena J. Reichert +2 more
wiley +1 more source
A Drosophila model of Barth syndrome [PDF]
Proceedings of the National Academy of Sciences, 2006 Barth syndrome is an X-linked disease presenting with cardiomyopathy and skeletal muscle weakness. It is caused by mutations in tafazzin, a putative acyl transferase that has been associated with altered metabolism of the mitochondrial phospholipid cardiolipin. To investigate the molecular basis of Barth syndrome, we created
Yang, Xu +6 more
openaire +2 more sources
Analyses of Social Issues and Public Policy, Volume 26, Issue 2, August 2026.Abstract This mixed‐methods study examines the experience of the impostor phenomenon in a racially/ethnically and sexually diverse sample of undergraduates in majors related to science, technology, engineering, and math (STEM). Guided by an intersectionality framework, we examined whether experiences of the impostor phenomenon differ at the ...
Richard Chang +3 more
wiley +1 more source
Forming moral community: Christian and ecclesial existence in the theology of Karl Barth 1915-1922 [PDF]
, 2008 This thesis is an investigation of Karl Barth's theology in the turbulent and dynamic years of his nascent career: 1915 - 1922, with a special focus on the manner in which he construed Christian and ecclesial existence.
O'Neil, Michael David
core
Frontiers in Physiology, 2021 Barth syndrome is a rare and incurable X-linked (male-specific) genetic disease that affects the protein tafazzin (Taz). Taz is an important enzyme responsible for synthesizing biologically relevant cardiolipin (for heart and skeletal muscle, cardiolipin
Mario Elkes +6 more
doaj +1 more source
Equine Veterinary Education, Volume 38, Issue 8, Page e509-e515, August 2026.Summary Gastric outflow obstruction (GOO) occasionally requires surgical intervention in foals when medical management fails. Current literature lacks consensus on several surgical decisions, with most comprehensive reports dating back over a decade. Critical aspects—including jejunal loop orientation and necessity of jejunojejunostomy—remain debated ...
P. Fernández Hernández +8 more
wiley +1 more source
Developmental Neurobiology, Volume 86, Issue 3, July 2026.ABSTRACT Zika virus (ZIKV) is an Orthoflavivirus known for its teratogenicity and for causing congenital Zika syndrome (CZS) in the offspring, but recent studies suggest a negative impact on maternal brain health and behavior following gestational ZIKV inoculation.
Meirylanne Gomes‐da‐Costa +10 more
wiley +1 more source