Proteins of Bartonella bacilliformis: Candidates for Vaccine Development. [PDF]
Bartonella bacilliformis is the etiologic agent of Carrión’s disease or Oroya fever. B. bacilliformis infection represents an interesting model of human host specificity. The notable differences in clinical presentations of Carrión’s disease suggest complex adaptations by the bacterium to the human host, with the overall objectives of persistence ...
Henriquez-Camacho C +4 more
europepmc +13 more sources
Co-infection with Bartonella bacilliformis and Mycobacterium spp. in a coastal region of Peru [PDF]
Objective This study investigated an outbreak of Bartonellosis in a coastal region in Peru. Results A total of 70 (n = 70) samples with clinical criteria for the acute phase of Bartonellosis and a positive peripheral blood smear were included. 22.85% (n =
Wilmer Silva-Caso +9 more
doaj +2 more sources
Molecular detection and clinical characteristics of Bartonella bacilliformis, Leptospira spp., and Rickettsia spp. in the Southeastern Peruvian Amazon basin [PDF]
Background Acute febrile illness (AFI) represent a significant health challenge in the Peruvian Amazon basin population due to their diverse etiologies and the unavailability of specific on-site diagnostic methods, resulting in underreporting of cases ...
Fiorella Ricapa-Antay +10 more
doaj +2 more sources
Seroprevalence and risk factors for infection with Bartonella bacilliformis in Loja province, Ecuador [PDF]
The seroprevalence and epidemiology of Bartonella bacilliformis infection in the Andean highlands of Ecuador is largely unknown. We conducted a sero-epidemiologic survey of 319 healthy children aged 1–15 years living in six rural, mountain communities in
Shari L. Lydy +4 more
doaj +2 more sources
Baculovirus-Assisted Production of Bartonella bacilliformis Proteins: A Potential Strategy for Improving Serological Diagnosis of Carrion’s Disease [PDF]
Carrion’s disease, caused by Bartonella bacilliformis, is a neglected tropical disease prevalent in the Andean region of South America. Without antimicrobial treatment, this disease has a mortality rate of up to 88% in infected patients.
Lizbeth Sally Vilca-Machaca +5 more
doaj +2 more sources
Combination antibiotic therapy is required to eliminate Bartonella henselae in multiple microenvironments [PDF]
Bartonella are gram-negative, facultative intracellular bacteria. Infection by Bartonella manifests as different clinical syndromes collectively known as bartonellosis.
Emily L. Olsen, Monica E. Embers
doaj +2 more sources
Porin A and α/β-hydrolase are necessary and sufficient for hemolysis induced by Bartonella bacilliformis [PDF]
Carrion’s disease is endemic to the South American Andes and is characterized by fatal hemolytic anemia. This neglected tropical disease is caused by Bartonella bacilliformis, a fastidious and slow-growing pathogen difficult in genetic manipulation.
Alexander A. Dichter +11 more
doaj +2 more sources
Mutation-Driven Divergence and Convergence Indicate Adaptive Evolution of the Intracellular Human-Restricted Pathogen, Bartonella bacilliformis. [PDF]
Among all species of Bartonella, human-restricted Bartonella bacilliformis is the most virulent but harbors one of the most reduced genomes. Carrión's disease, the infection caused by B.
Sandip Paul +2 more
doaj +2 more sources
BALB/c Mice resist infection with
Background Bartonellosis due to Bartonella bacilliformis is a highly lethal endemic and sometimes epidemic infectious disease in South America, and a serious public health concern in Perú.
Manguiña Ciro +10 more
doaj +3 more sources
Molecular Characterization of Fluoroquinolone-Resistant Bartonella bacilliformis. [PDF]
The presence of amino acid changes in GyrA, GyrB, ParC, ParE, and in a proposed chromosomal chloramphenicol acetyl transferase (CAT), as well as mutations at 23S rRNA, were established by PCR and sequencing in 38 B. bacilliformis clinical isolates from four different areas in Peru.
Mendoza-Mujica G +2 more
europepmc +5 more sources

