Large-scale identification of pathogenicity factors in "Bartonella" by signature-tagged mutagenesis [PDF]
Bartonellae are bacterial pathogens uniquely adapted to cause intraerythrocytic infection in their mammalian reservoir hosts. In the case of human-specific Bartonella bacilliformis and Bartonella quintana, the intraerythrocytic bacteremia leads to the ...
Saenz Dürrmeier, Luis-Henri
core +1 more source
Invasion and persistent intracellular colonization of erythrocytes : A unique parasitic strategy of the emerging pathogen Bartonella [PDF]
The expanding genus Bartonella includes zoonotic and human-specific pathogens that can cause a wide range of clinical manifestations. A productive infection allowing bacterial transmission by blood-sucking arthropods is marked by an intraerythrocytic ...
Schulein, R. +13 more
core +1 more source
The protein–protein interactions required for assembly of the Tn3 resolution synapse
The site‐specific recombinase Tn3 resolvase builds an intricate protein‐DNA complex (synapse) prior to cutting and rejoining DNA strands. We used a novel complementation strategy involving hybrids of Tn3 resolvase and a related enzyme, Bart resolvase, to show that a specific protein‐protein “R” interface is used by all the DNA‐bound resolvase dimers in
Sally‐J. Rowland +4 more
wiley +1 more source
The role of the VirB/VirD4/Bep system in "Bartonella henselae"-triggered vascular proliferation [PDF]
Bartonella henselae (Bh) rarely shows any symptoms in its feline reservoir host but is responsible for a number of clinical outcomes during infection of the human incidental host. Bh shares with B. quintana (Bq) and B.
Scheidegger, Florine
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From FIC to BID : target identification and functional characterization of "Bartonella" effector proteins [PDF]
Pathogens belonging to the genus Bartonella employ a unique stealth infection strategy that involves evasion from the host immune system, replication in the endothelium and persistence in erythrocytes.
Pieles, Kathrin
core +1 more source
JMM Profile: Bartonella bacilliformis: a forgotten killer
Bartonella bacilliformis causes Carrión's disease, an infectious disease present in rural Andean areas of Peru and Ecuador. The disease has an acute and a chronic phase called Oroya fever and Peruvian wart, respectively.
Ruiz, J.
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Carrion’s disease: more than a neglected disease
Infections with Bartonella bacilliformis result in Carrion’s disease in humans. In the first phase of infection, the pathogen causes a hemolytic fever (“Oroya fever”) with case-fatality rates as high as ~90% in untreated patients, followed by a chronical
Meritxell Garcia-Quintanilla +3 more
doaj +1 more source
Multi-locus sequence analysis reveals profound genetic diversity among isolates of the human pathogen Bartonella bacilliformis. [PDF]
Bartonella bacilliformis is the aetiological agent of human bartonellosis, a potentially life threatening infection of significant public health concern in the Andean region of South America. Human bartonellosis has long been recognised in the region but
Gemma L Chaloner +2 more
doaj +1 more source
BackgroundIn Peru, the information regarding sand fly vectors of leishmaniasis and bartonellosis in the Amazon region is limited. In this study, we carried out sand fly collections in Peruvian lowland and highland jungle areas using different trap type ...
Victor O Zorrilla +10 more
doaj +1 more source
Cutaneous manifestations of bartonellosis [PDF]
Bartonellosis are diseases caused by any kind of Bartonella species. The infection manifests as asymptomatic bacteremia to potentially fatal disorders.
Karina de Almeida Lins +2 more
doaj +2 more sources

