Characterization and expression analysis of the groESL operon of Bartonella bacilliformis [PDF]
The groESL operon of Bartonella bacilliformis, a facultative intracellular, Gram-negative bacterium and etiologic agent of Oroya Fever, was characterized. Sequence analysis revealed an operon containing two genes of 294 (groES) and 1632 nucleotides (groEL) separated by a 55-nt intergenic spacer. The operon is preceded by a 72-nt ORF (ORF1) that encodes
Julie A, Callison +4 more
openaire +2 more sources
Cutaneous manifestations of bartonellosis [PDF]
Bartonellosis are diseases caused by any kind of Bartonella species. The infection manifests as asymptomatic bacteremia to potentially fatal disorders.
Karina de Almeida Lins +2 more
doaj +2 more sources
Multi-locus sequence analysis reveals profound genetic diversity among isolates of the human pathogen Bartonella bacilliformis. [PDF]
Bartonella bacilliformis is the aetiological agent of human bartonellosis, a potentially life threatening infection of significant public health concern in the Andean region of South America. Human bartonellosis has long been recognised in the region but
Gemma L Chaloner +2 more
doaj +1 more source
Molecular Detection of Bartonella spp. in China and St. Kitts
Bartonella are vector‐borne hemotropic bacteria that infect a wide variety of hosts, including people. While there are PCR assays that can identify individual or groups of Bartonella, there is no reliable molecular method to simultaneously detect all species while maintaining genus specificity and sensitivity.
Ke Huang +7 more
wiley +1 more source
Adhesion to and invasion of cultured human cells by Bartonella bacilliformis [PDF]
Bartonella bacilliformis was tested for its ability to adhere to and invade tissue culture cell monolayers. The parasite was able to efficiently bind and penetrate human dermal fibroblasts, human laryngeal epithelium, and human umbilical vein endothelial cells.
E M, Hill +4 more
openaire +2 more sources
Semantic Modeling for Exposomics with Exploratory Evaluation in Clinical Context
Exposome is a critical dimension in the precision medicine paradigm. Effective representation of exposomics knowledge is instrumental to melding nongenetic factors into data analytics for clinical research. There is still limited work in (1) modeling exposome entities and relations with proper integration to mainstream ontologies and (2) systematically
Jung-wei Fan +3 more
wiley +1 more source
Development and characterisation of highly antibiotic resistant Bartonella bacilliformis mutants. [PDF]
AbstractThe objective was to develop and characterise in vitro Bartonella bacilliformis antibiotic resistant mutants. Three B. bacilliformis strains were plated 35 or 40 times with azithromycin, chloramphenicol, ciprofloxacin or rifampicin discs. Resistance-stability was assessed performing 5 serial passages without antibiotic pressure.
Gomes C +5 more
europepmc +5 more sources
Highly Sensitive Loop‐Mediated Isothermal Amplification for the Detection of Leptospira
Leptospirosis is a worldwide zoonosis caused by an infection with the pathogenic species of Leptospira. We have developed a loop‐mediated isothermal amplification (LAMP) assay to detect the DNA of Leptospira spp. Six sets of primers targeting the gene of the subsurface protein, lipL32, were evaluated for their detection sensitivity. The best primer set
Hua-Wei Chen +6 more
wiley +1 more source
Interplay of the Gastric Pathogen Helicobacter pylori with Toll‐Like Receptors
Toll‐like receptors (TLRs) are crucial for pathogen recognition and downstream signaling to induce effective immunity. The gastric pathogen Helicobacter pylori is a paradigm of persistent bacterial infections and chronic inflammation in humans. The chronicity of inflammation during H.
Suneesh Kumar Pachathundikandi +5 more
wiley +1 more source
Cutaneous leishmaniasis (CL) is endemic in Khyber Pakhtunkhwa (KP) Province of Pakistan, and exploring its epidemiological status is critical for its control. The current study described the spatial occurrence of CL and its associated risk factors in KP.
Khurshaid Khan +5 more
wiley +1 more source

