Baculovirus-Assisted Production of Bartonella bacilliformis Proteins: A Potential Strategy for Improving Serological Diagnosis of Carrion’s Disease [PDF]
Carrion’s disease, caused by Bartonella bacilliformis, is a neglected tropical disease prevalent in the Andean region of South America. Without antimicrobial treatment, this disease has a mortality rate of up to 88% in infected patients.
Lizbeth Sally Vilca-Machaca +5 more
doaj +2 more sources
Porin A and α/β-hydrolase are necessary and sufficient for hemolysis induced by Bartonella bacilliformis [PDF]
Carrion’s disease is endemic to the South American Andes and is characterized by fatal hemolytic anemia. This neglected tropical disease is caused by Bartonella bacilliformis, a fastidious and slow-growing pathogen difficult in genetic manipulation.
Alexander A. Dichter +11 more
doaj +2 more sources
Mutation-Driven Divergence and Convergence Indicate Adaptive Evolution of the Intracellular Human-Restricted Pathogen, Bartonella bacilliformis. [PDF]
Among all species of Bartonella, human-restricted Bartonella bacilliformis is the most virulent but harbors one of the most reduced genomes. Carrión's disease, the infection caused by B.
Sandip Paul +2 more
doaj +2 more sources
Molecular Characterization of Fluoroquinolone-Resistant Bartonella bacilliformis. [PDF]
The presence of amino acid changes in GyrA, GyrB, ParC, ParE, and in a proposed chromosomal chloramphenicol acetyl transferase (CAT), as well as mutations at 23S rRNA, were established by PCR and sequencing in 38 B. bacilliformis clinical isolates from four different areas in Peru.
Mendoza-Mujica G +2 more
europepmc +5 more sources
Colonization of Lutzomyia verrucarum and Lutzomyia longipalpis Sand Flies (Diptera: Psychodidae) by Bartonella bacilliformis, the Etiologic Agent of Carrión's Disease. [PDF]
Bartonella bacilliformis is a pathogenic bacterium transmitted to humans presumably by bites of phlebotomine sand flies, infection with which results in a bi-phasic syndrome termed Carrión's disease. After constructing a low-passage GFP-labeled strain of
James M Battisti +2 more
doaj +2 more sources
Rapid and sensitive detection of Bartonella bacilliformis in experimentally infected sand flies by loop-mediated isothermal amplification (LAMP) of the Pap31 gene. [PDF]
Carrion' disease, caused by Bartonella bacilliformis, remains truly neglected due to its focal geographical nature. A wide spectrum of clinical manifestations, including asymptomatic bacteremia, and lack of a sensitive diagnostic test can potentially ...
Nasikarn Angkasekwinai +5 more
doaj +2 more sources
Detección de Bartonella bacilliformis usando PCR-RFLP
Reportamos la aplicación de las técnicas moleculares PCR-RFLP para la confirmación de infecciones por Bartonella bacilliformis. El método de PCR-RFLP se basa en la amplificación in vitro de un fragmento de 380 pb correspondiente al gen citrato sintetasa ...
C Padilla +4 more
doaj +2 more sources
Identificación de Bartonella bacilliformis por métodos moleculares
Introducción: La técnica de PCR amplifica una secuencia de ADN con la enzima polimerasa; es muy sensible y específica. Objetivo: Estandarizar una técnica de PCR para identificar Bartonella bacilliformis en sangre total de pacientes con bartonelosis aguda.
César Henríquez +8 more
doaj +3 more sources
Complete Genome Sequence of Bartonella bacilliformis Strain KC584 (ATCC 35686). [PDF]
Bartonella bacilliformis is the biological agent of Carrion’s disease, a vector-borne, life-threatening human bartonellosis restricted to South America. Here, we report the complete genome sequence of B. bacilliformis KC584 (ATCC 35686).
Dichter AA +4 more
europepmc +4 more sources
We compared sand fly communities of a forest reserve with those of forest management areas in Mexico to determine their species diversity (α and β) and determined peaks of activity. During the windy and dry season, the abundance of anthropophilic sand fly species is negatively correlated with the temperature and positively correlated with relative ...
Maribel Martínez‐Burgos +8 more
wiley +1 more source

