Results 91 to 100 of about 32,167,916 (377)
A working model for cytoplasmic assembly of H/ACA snoRNPs
FEBS Letters, EarlyView.Dyskerin is the component of nuclear H/ACA ribonucleoproteins (RNPs) endowed with pseudouridine synthase catalytic activity. Two isoforms of human dyskerin have been characterized: the abundant Iso1, mainly nuclear, and the shorter Iso3, mainly cytoplasmic but occasionally imported into nuclei.
Alberto Angrisani, Maria Furia
wiley +1 more source
Planar cell polarity coordination in a cnidarian embryo provides clues to animal body axis evolution
eLifeBody axis specification is a crucial event in animal embryogenesis and was an essential evolutionary innovation for founding the animal kingdom. This process involves two distinct components that coordinate to establish the spatial organisation of the ...
Julie Uveira +7 more
doaj +1 more source
FEBS Letters, EarlyView.Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican +7 more
wiley +1 more source
Basal Temperature, Cervical Mucous, and Both Combination as Diagnostic Tools to Detect Ovulation
Indonesian Journal of Obstetrics and Gynecology, 2018 Objective: To make basal body temperature examination and cervical mucus as an alternative examination in detecting ovulation, especially in health facilities that do not have ultrasound.
Eka R Gunardi +2 more
doaj +1 more source
Central American Temnocerus Thunberg, 1815 (Coleoptera: Rhynchitidae) [PDF]
, 2010 Twenty eight species of Temnocerus Thunberg, 1815 are recognized from Central America (Mexico to Panama) with eight previously described species and 20 new species as follows: T. abdominalis (Voss), T. chiapensis n. sp., T.
Hamilton, R. W.
core +1 more source
Novel and unscrutinized immune entities of the zebrafish gut
FEBS Letters, EarlyView.Understudied cells of the zebrafish immune system include bona fide immune cells and epithelial (‐derived) cells with immune functions. Research focusing on zebrafish cells which demonstrate similarities to mammalian immune cell counterparts may help us understand the pathologies in which they are implicated. Currently available and advanced tools make
Audrey Inge Schytz Andersen‐Civil +5 more
wiley +1 more source
Prickle3 synergizes with Wtip to regulate basal body organization and cilia growth
Scientific Reports, 2016 PCP proteins maintain planar polarity in many epithelial tissues and have been implicated in cilia development in vertebrate embryos. In this study we examine Prickle3 (Pk3), a vertebrate homologue of Drosophila Prickle, in Xenopus gastrocoel roof plate (
C. Chu +3 more
semanticscholar +1 more source
European Journal of Taxonomy, 2021 Five new and five known species of the genus Tylencholaimus de Man, 1876 are described from the Western Ghats of India. Tylencholaimus macroamphidius sp. nov.
Md Niraul Islam, Wasim Ahmad
doaj +1 more source
Early postnatal caloric restriction protects adult male intrauterine growth-restricted offspring from obesity. [PDF]
, 2012 Postnatal ad libitum caloric intake superimposed on intrauterine growth restriction (IUGR) is associated with adult-onset obesity, insulin resistance, and type 2 diabetes mellitus (T2DM).
Dai, Yun +6 more
core +1 more source
Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells
FEBS Letters, EarlyView.Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura +8 more
wiley +1 more source