Results 121 to 130 of about 31,542,963 (350)

Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation

open access: yesFEBS Letters, EarlyView.
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt   +8 more
wiley   +1 more source

Chibby promotes ciliary vesicle formation and basal body docking during airway cell differentiation

open access: yesJournal of Cell Biology, 2014
In the early stages of cilia formation in the mouse airway epithelium, Chibby is recruited to the distal appendages of centrioles and is necessary for efficient ciliary vesicle formation and basal body docking at the apical cell membrane.
Michael C. Burke   +13 more
semanticscholar   +1 more source

Purification tags markedly affect self‐aggregation of CPEB3

open access: yesFEBS Letters, EarlyView.
Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito   +6 more
wiley   +1 more source

Indices of adrenal cortical activity in men exposed to cold [PDF]

open access: yes, 1951
Thesis (M.A.)--Boston UniversityEvidence of physiological acclimatization of man to cold is scanty and not clear-cut. Certainly no adaptations have been described comparable to the dramatic changes which occur when men are acclimatized to heat.
Bass, David E.
core   +1 more source

Regulating basal body replication

open access: yesThe Journal of Cell Biology, 2005
![Graphic][1] Mutant γ-tubulin (right) results in extra basal bodies.Cells tightly regulate the replication of centrioles, which form the heart of centrosomes. But Shang et al.
openaire   +3 more sources

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

open access: yesMolecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever   +1 more
wiley   +1 more source

Simple Skeletal Muscle Mass Estimation Formulas: What We Can Learn From Them

open access: yesFrontiers in Endocrinology, 2020
One century ago Harris and Benedict published a short report critically examining the relations between body size, body shape, age, and basal metabolic rate.
Steven B. Heymsfield   +4 more
doaj   +1 more source

Clinical applications of next‐generation sequencing‐based ctDNA analyses in breast cancer: defining treatment targets and dynamic changes during disease progression

open access: yesMolecular Oncology, EarlyView.
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker   +14 more
wiley   +1 more source

Input Sources and Properties of Position-Sensitive Oculomotor Fibres in the Rock Lobster, Panulirus Interruptus (Randall) [PDF]

open access: yes, 1972
Sets of head-up, head-down, eye-up and eye-down motor fibres were studied in the oculomotor nerve of the rock lobster. An eye-withdrawal fibre was also investigated.
Wiersma, C. A. G.   +2 more
core  

An essential role of the basal body protein SAS-6 in Plasmodium male gamete development and malaria transmission

open access: yesCellular Microbiology, 2014
Gametocytes are the sole Plasmodium parasite stages that infect mosquitoes; therefore development of functional gametes is required for malaria transmission.
S. Marques   +6 more
semanticscholar   +1 more source

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