Results 151 to 160 of about 31,542,963 (350)

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

ESTIMATION OF OVARIAN ACTIVITY BY THE CONSECUTIVEDAY STUDY OF BASAL BODY TEMPERATURE AND BASAL METABOLIC RATE1 [PDF]

, 1938
Boris B. Rubenstein
openalex   +1 more source

FAM161A, associated with retinitis pigmentosa, is a component of the cilia-basal body complex and interacts with proteins involved in ciliopathies.

Human Molecular Genetics, 2012
Retinitis pigmentosa (RP) is a retinal degenerative disease characterized by the progressive loss of photoreceptors. We have previously demonstrated that RP can be caused by recessive mutations in the human FAM161A gene, encoding a protein with unknown ...
Silvio Alessandro Di Gioia, S. Letteboer, C. Kostic, Dikla Bandah-Rozenfeld, L. Hetterschijt, D. Sharon, Y. Arsenijevic, R. Roepman, C. Rivolta   +8 more
semanticscholar   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

BASAL CARDIAC FUNCTION AND BODY COMPOSITION WITH SPECIAL REFERENCE TO OBESITY 1 [PDF]

, 1952
Henry L. Taylor, Josef Brožek, Ancel Keys, Walter M. Carlson   +3 more
openalex   +1 more source

Time, the final frontier

Molecular Oncology, EarlyView.
This article advocates integrating temporal dynamics into cancer research. Rather than relying on static snapshots, researchers should increasingly consider adopting dynamic methods—such as live imaging, temporal omics, and liquid biopsies—to track how tumors evolve over time.
Gautier Follain, Michal Dibus, Omkar Joshi, Guillaume Jacquemet   +3 more
wiley   +1 more source

CIRCULATORY DYNAMICS IN THE BASAL STATE OBSERVED DURING CONVALESCENCE. CHANGES IN BODY WEIGHT, BLOOD VOLUME, AND VENOUS PRESSURE 12 [PDF]

, 1947
George R. Meneely, Albert Segaloff, Elisabeth Wells   +2 more
openalex   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

Molecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson, Emma L. Dorward, Kristyn Jurrius, Nathalie Nataren, Markus Tondl, Kay K. Myo Min, Michaelia P. Cockshell, Anahita Fouladzadeh, John Toubia, Mark DeNichilo, Delphine Merino, Claudine S. Bonder   +11 more
wiley   +1 more source

Association between the Age of Onset of Obesity and Energy Metabolism in Adulthood Among Overweight and Obese Women

مجله دانشگاه علوم پزشکی گرگان, 2021
Background and Objective: Obesity plays an important role in the development of chronic diseases including diabetes, hyperlipidemia, and cardiovascular diseases (CVD).
Habib Yarizadeh, Leila Setayesh, Seyed Ali Keshavarz, Khadijeh Mirzaei   +3 more
doaj  

THE FREQUENCY OF ADENO-CARCINOMA OF THE BODY IN FIBROID TUMOURS OF THE UTERUS: BASED ON A SERIES OF TWO HUNDRED CASES OF ABDOMINAL HYSTERECTOMY [PDF]

, 1910
J. M. Munro Kerr
openalex   +1 more source