Results 1 to 10 of about 51,665 (147)

Suprabasal cells retain progenitor cell identity programs in eosinophilic esophagitis–driven basal cell hyperplasia [PDF]

JCI Insight, 2023
Eosinophilic esophagitis (EoE) is an esophageal immune-mediated disease characterized by eosinophilic inflammation and epithelial remodeling, including basal cell hyperplasia (BCH).
Margarette H. Clevenger, Adam L. Karami, Dustin A. Carlson, Peter J. Kahrilas, Nirmala Gonsalves, John E. Pandolfino, Deborah R. Winter, Kelly A. Whelan, Marie-Pier Tétreault   +8 more
doaj   +4 more sources

Molecular pathogenesis of human prostate basal cell hyperplasia [PDF]

Prostate, 2017
BackgroundUnderstanding the molecular pathogenesis of distinct phenotypes in human benign prostatic hyperplasia (BPH) is essential to improving therapeutic intervention. Current therapies target smooth muscle and luminal epithelia for relief of lower urinary tract symptoms (LUTS) due to BPH, but basal cell hyperplasia (BCH) remains untargeted.
José Torrealba, Ryan Mauck, Gervaise Henry   +2 more
exaly   +5 more sources

Case Report: Two cases of bronchiolar adenoma/ciliated muconodular papillary tumor characterized by significant basal cell hyperplasia and squamous metaplasia [PDF]

Frontiers in Oncology
BackgroundBronchiolar adenoma/ciliated muconodular papillary tumor (BA/CMPT) is a rare benign pulmonary tumor from the bronchiolar epithelium. Histologically, it features a continuous basal cell layer and luminal cells.
Ziran Gao, Qiang Feng, Yuanyuan Wang, Ya Jiang, Dan Han, Wenmang Xu   +5 more
doaj   +4 more sources

Basal Cell Hyperplasia in the Peripheral Zone of the Prostate [PDF]

Modern Pathology, 2003
Basal cell hyperplasia in the prostate is often viewed as a transition zone proliferation, related to usual, nodular glandular, and stromal hyperplasia. Basal cell hyperplasia in the prostatic peripheral zone, the most common site for development of prostatic intraepithelial neoplasia and carcinoma, has not been previously characterized.
Paul Swanson, Robin T Vollmer, Peter A Humphrey   +2 more
exaly   +3 more sources

Mitochondrial dysfunction drives basal cell hyperplasia in eosinophilic oesophagitis. [PDF]

Gut
Background Eosinophilic oesophagitis (EoE) is a food allergen-induced inflammatory disorder characterised by interleukin (IL)-13-mediated oesophageal inflammation and epithelial basal cell hyperplasia (BCH). The role of mitochondria in EoE pathogenesis remains elusive.
Morimoto M, Kawasaki K, McNamee N, Flashner S, Shimonosono R, Shimonosono M, Matsuura N, Tomita Y, Hirose W, Teranishi R, Itami T, Guha M, Rajagopalan P, Martin C, Golden H, Dhakal D, Wilkins BJ, Klein-Szanto AJ, Wangensteen KJ, Abrams JA, Pomenti S, Katzka DA, Que J, Whelan KA, Muir AB, Kita H, Wright BL, Doyle AD, Nakagawa H, Sachdeva UM.   +29 more
europepmc   +3 more sources

IL-33/IL1RL1 (ST2) signalling drives immune suppression in squamous intraepithelial hyperplasia [PDF]

Tumour Virus Research
IL-33, an alarmin cytokine binding to IL1RL1 (ST2) receptor, plays a multifaceted role in cancer. Using an HPV16-E7 oncoprotein-mediated murine model of squamous intraepithelial hyperplasia, a pre-stage of squamous cell carcinoma (SCC), we characterised ...
Chenhao Zhou, Jazmina Gonzalez Cruz, Siok Min Teoh, Minh Tran, Denise Goh, Divyaa Narayanan, Xiao Tan, Thi Viet Trinh Dang, Zewen Kelvin Tuong, Kevin Gillinder, Abate Bashaw, James W. Wells, Ian H. Frazer, Quan Nguyen, Yu Chen, Meihua Yu, Janin Chandra   +16 more
doaj   +2 more sources

Integrated Single-Cell and Bulk RNA Sequencing Reveals Inflammatory Microenvironment and Glycolysis-Driven Epithelial Proliferation in Benign Prostatic Hyperplasia [PDF]

Journal of Inflammation Research
Jianchao Ge, Wei Jiao, Wandong Yu, Guowei Shi, Xilong Wang, Jun ZhangDepartment of Urology, The Fifth People’s Hospital of Shanghai, Fudan University, Shanghai, People’s Republic of China*These authors contributed equally to this ...
Ge J, Jiao W, Yu W, Shi G, Wang X, Zhang J   +5 more
doaj   +2 more sources

Basal cell hyperplasia of prostate - an entity a urologist must know

Indian Journal of Urology, 2000
We report 2 cases of basal cell hyperplasia of prostate, which is an uncommon and elusive lesion. It is commonly associated with benign prostatic hyperplasia (BPH) and may sometimes be mistaken for malignancy.
Suresh Bhat, Appu Thomas, M Nazar, George C Joseph, Dharmaraj   +4 more
doaj   +2 more sources

Persistent Basal Cell Hyperplasia Is Associated With Clinical and Endoscopic Findings in Patients With Histologically Inactive Eosinophilic Esophagitis [PDF]

Clinical Gastroenterology and Hepatology, 2020
Medha Sharma, Hiroshi Nakagawa, Jonathan Gross   +2 more
exaly   +2 more sources

Hyaluronidases and hyaluronan synthases expression is inversely correlated with malignancy in lung/bronchial pre-neoplastic and neoplastic lesions, affecting prognosis [PDF]

Brazilian Journal of Medical and Biological Research, 2015
We collected a series of 136 lung/bronchial and 56 matched lung parenchyma tissue samples from patients who underwent lung/bronchial biopsies and presented invasive carcinoma after lung surgery. The lung/bronchial samples included basal cell hyperplasia,
V.K. de Sá, T.P. Rocha, AL. Moreira, F.A. Soares, T. Takagaki, L. Carvalho, A.G. Nicholson, V.L. Capelozzi   +7 more
doaj   +3 more sources