Results 111 to 120 of about 26,837,992 (363)
PLoS Comput. Biol., 2017 Motor tics are a cardinal feature of Tourette syndrome and are traditionally associated with an excess of striatal dopamine in the basal ganglia. Recent evidence increasingly supports a more articulated view where cerebellum and cortex, working closely ...
Daniele Caligiore +3 more
semanticscholar +1 more source
Upconversion‐Based Remote Deep Brain Modulation for Therapeutic Dissection of Parkinson's Disease
Advanced Therapeutics, EarlyView.An upconversion‐based wireless optogenetic strategy enables an all‐optical deep brain modulation solution for treating Parkinson's disease in rodent animals without using electronics or any tethered cables, providing experimental evidence supporting a therapeutic mechanism of STN‐DBS by disruption of anterograde signal transmission along the indirect ...
Wenchong Zhang +13 more
wiley +1 more source
White matter abnormalities in depression: A categorical and phenotypic diffusion MRI study
NeuroImage: Clinical, 2019 Mood depressive disorder is one of the most disabling chronic diseases with a high rate of everyday life disability that affects 350 million people around the world.
Julie Coloigner +6 more
doaj
Thalamic interactions of cerebellum and basal ganglia
Brain Structure and Function, 2017 Cerebellum and basal ganglia are reciprocally interconnected with the neocortex via oligosynaptic loops. The signal pathways of these loops predominantly converge in motor areas of the frontal cortex and are mainly segregated on subcortical level. Recent
Andreas Hintzen +2 more
semanticscholar +1 more source
Accelerated Bone Healing via Electrical Stimulation
Advanced Science, EarlyView.Electrical stimulation significantly impacts bone healing by enhancing osteoblast proliferation, differentiation, and vascularization through calmodulin/calcineurin/NFAT signaling. It also boosts macrophage function and cell migration, presenting a comprehensive approach to accelerating bone repair.
Jianfeng Sun +4 more
wiley +1 more source
Posttraumatic Bilateral Basal Ganglia Bleed: A Report of Three Extremely Rare Cases
Indian Journal of Neurosurgery, 2019 Basal ganglia bleed, though common in hypertensive, is unusual in posttraumatic patients. Bilateral basal ganglia hematoma following trauma is extremely rare and is limited to few case reports.
Musali Siddartha Reddy +3 more
doaj +1 more source
Saccade learning with concurrent cortical and subcortical basal ganglia loops [PDF]
arXiv, 2013 The Basal Ganglia is a central structure involved in multiple cortical and subcortical loops. Some of these loops are believed to be responsible for saccade target selection. We study here how the very specific structural relationships of these saccadic loops can affect the ability of learning spatial and feature-based tasks.
arxiv
Deep brain stimulation for movement disorder treatment: Exploring frequency-dependent efficacy in a computational network model [PDF]
arXiv, 2020 A large scale computational model of the basal ganglia (BG) network is proposed to describes movement disorder including deep brain stimulation (DBS). The model of this complex network considers four areas of the basal ganglia network: the subthalamic nucleus (STN) as target area of DBS, globus pallidus, both pars externa and pars interna (GPe-GPi ...
arxiv
It's not just the basal ganglia: Cerebellum as a target for dystonia therapeutics
Movement Disorders, 2017 Dystonia is a common movement disorder that devastates the lives of many patients, but the etiology of this disorder remains poorly understood. Dystonia has traditionally been considered a disorder of the basal ganglia. However, growing evidence suggests
Ambika Tewari +2 more
semanticscholar +1 more source
Advanced Science, EarlyView.Lycium barbarum glycopeptide (LBGP), which is further extracted from Lycium barbarum polysaccharides, exhibits significant protective effects against neomycin‐induced hearing dysfunction including oxidative stress in cochlea and loss of key cells in cochlea.
Yunhao Wu +12 more
wiley +1 more source