Results 121 to 130 of about 27,335,908 (329)

Electrophysiological signatures of anxiety in Parkinson’s disease

open access: yesTranslational Psychiatry
Anxiety is a common non-motor symptom in Parkinson’s disease (PD) occurring in up to 31% of the patients and affecting their quality of life. Despite the high prevalence, anxiety symptoms in PD are often underdiagnosed and, therefore, undertreated.
Sahar Yassine   +6 more
doaj   +1 more source

New Perspectives on Semiconducting Conjugated Oligomers for Neuromodulation in Hydra vulgaris

open access: yesAdvanced Materials Interfaces, EarlyView.
Semiconducting organic compounds, thiophene‐based, modify the rhythmic electrical activity of the cnidarian Hydra vulgaris acting on specific neuronal circuits. The ETE‐S trimer also forms electronically conducting wires in the living tissues of the animal.
Giuseppina Tommasini   +7 more
wiley   +1 more source

Posttraumatic Bilateral Basal Ganglia Bleed: A Report of Three Extremely Rare Cases

open access: yesIndian Journal of Neurosurgery, 2019
Basal ganglia bleed, though common in hypertensive, is unusual in posttraumatic patients. Bilateral basal ganglia hematoma following trauma is extremely rare and is limited to few case reports.
Musali Siddartha Reddy   +3 more
doaj   +1 more source

Bioengineered Models of Nerve Regeneration

open access: yesAdvanced Materials Technologies, EarlyView.
Bioengineered nerve regeneration platforms ranging from patterned cell cultures and hydrogels to fibrous scaffolds and microfluidic systems are reviewed, highlighting the complex cellular and biochemical environments essential for nerve repair. Challenges associated with these platforms, such as balancing complexity with throughput and the need for ...
Madalynn Jade Thompson   +1 more
wiley   +1 more source

White matter abnormalities in depression: A categorical and phenotypic diffusion MRI study

open access: yesNeuroImage: Clinical, 2019
Mood depressive disorder is one of the most disabling chronic diseases with a high rate of everyday life disability that affects 350 million people around the world.
Julie Coloigner   +6 more
doaj  

Evolution of Ocular Organ‐On‐Chip Systems for Disease Modelling and Drug Testing: Where are We Now?

open access: yesAdvanced Therapeutics, EarlyView.
The rise in ophthalmic diseases due to aging, screen use, and environmental factors has driven demand for better ocular models. Traditional systems fall short, encouraging the development of organ‐on‐chip devices. These microfluidic platforms replicate eye tissue architecture, enable drug screening, and simulate ocular diseases.
Sara Trujillo
wiley   +1 more source

Learning Reward Uncertainty in the Basal Ganglia

open access: yesPLoS Comput. Biol., 2016
Learning the reliability of different sources of rewards is critical for making optimal choices. However, despite the existence of detailed theory describing how the expected reward is learned in the basal ganglia, it is not known how reward uncertainty ...
John G. Mikhael, R. Bogacz
semanticscholar   +1 more source

Exploring AAV‐Mediated Gene Therapy for Inner Ear Diseases: from Preclinical Success to Clinical Potential

open access: yesAdvanced Science, EarlyView.
Current preclinical studies of AAV‐mediated gene therapy explore different strategies based on the characteristics of inner ear diseases. For genetic hearing loss, approaches include the replacement of a “good gene,” removal of a “bad gene,” or direct correction of mutations through base editing.
Fan Wu   +7 more
wiley   +1 more source

Patients with schizophrenia show aberrant patterns of basal ganglia activation: Evidence from ALE meta-analysis

open access: yesNeuroImage: Clinical, 2017
The diverse circuits and functional contributions of the basal ganglia, coupled with known differences in dopaminergic function in patients with schizophrenia, suggest they may be an important contributor to the etiology of the hallmark symptoms and ...
Jessica A. Bernard   +4 more
doaj   +1 more source

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